


Mefsyl 500mg/500mg Tablet
Ethamsylate (500mg)+ Mefenamic Acid (500mg)
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Mefsyl 500mg/500mg Tablet is a combination medicine used in the treatment of bleeding. It works by preventing the breakdown of clots and controls excessive bleeding during menstruation (periods).
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 21 Sep 2025 | 05:42 PM (IST)
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 21 Sep 2025 | 05:42 PM (IST)
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General Information
Contains
Ethamsylate (500mg)+ Mefenamic Acid (500mg)
Marketer
Ardor Drugs Pvt Ltd
Storage
Store below 30°C
The content is shown in English



Product introduction
Mefsyl 500mg/500mg Tablet should be taken with food to avoid stomach upset. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better.
It may cause side effects like skin rash, headache, nausea, and loss of appetite. These are usually mild but let your doctor know if they bother you or last more than a few days. Before taking this medicine, let your doctor know if you have liver or kidney problems, or you are pregnant or breastfeeding. It might cause dizziness, if happens better to avoid driving or machinery work. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.
It may cause side effects like skin rash, headache, nausea, and loss of appetite. These are usually mild but let your doctor know if they bother you or last more than a few days. Before taking this medicine, let your doctor know if you have liver or kidney problems, or you are pregnant or breastfeeding. It might cause dizziness, if happens better to avoid driving or machinery work. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.
Uses of Mefsyl Tablet
Benefits of Mefsyl Tablet
Bleeding
Mefsyl 500mg/500mg Tablet helps normal blood clotting, which reduces the bleeding during menstruation. It helps to prevent excessive loss of blood, stops bleeding and enhances the healing process. Mefsyl 500mg/500mg Tablet blocks certain chemicals that causes pain and thus gives relief. This helps prevent complications of excessive bleeding such as hemorrhage. It is advisable to use the medicine as prescribed for it to be effective.
Mefsyl 500mg/500mg Tablet helps normal blood clotting, which reduces the bleeding during menstruation. It helps to prevent excessive loss of blood, stops bleeding and enhances the healing process. Mefsyl 500mg/500mg Tablet blocks certain chemicals that causes pain and thus gives relief. This helps prevent complications of excessive bleeding such as hemorrhage. It is advisable to use the medicine as prescribed for it to be effective.
Side effects of Mefsyl Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mefsyl
- Skin rash
- Headache
- Nausea
- Vomiting
- Heartburn
- Indigestion
- Diarrhea
- Loss of appetite
How to use Mefsyl Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mefsyl 500mg/500mg Tablet is to be taken with food.
How Mefsyl Tablet works
Mefsyl 500mg/500mg Tablet is a combination of two medicines: Ethamsylate and Mefenamic Acid. Ethamsylate is an antifibrinolytic. It works by preventing the breakdown of clots and controls excessive bleeding during menstruation (periods). Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID) which blocks the production of certain chemical messengers (prostaglandins) that cause pain and inflammation (redness and swelling).
All substitutes for Mefsyl 500mg/500mg Tablet
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- Mefsyl 500mg/500mg Tablet helps reduce blood loss.
- Take it with a light snack or meal to avoid stomach upset.
- Stick to simple meals and avoid spicy rich food in order to avoid feeling sick (nausea).
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Mefsyl 500mg/500mg Tablet.

Pregnancy
CONSULT YOUR DOCTOR
Mefsyl 500mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Mefsyl 500mg/500mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving
UNSAFE
Mefsyl 500mg/500mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
CAUTION
Mefsyl 500mg/500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Mefsyl 500mg/500mg Tablet may be needed. Please consult your doctor.
Use of Mefsyl 500mg/500mg Tablet is not recommended in patients with severe kidney disease.
Use of Mefsyl 500mg/500mg Tablet is not recommended in patients with severe kidney disease.

Liver
CAUTION
Mefsyl 500mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Mefsyl 500mg/500mg Tablet may be needed. Please consult your doctor.

Fact Box
Habit Forming
No
Therapeutic Class
BLOOD RELATED
References
- Mefenamic Acid. Atlanta, Georgia: Sciele Pharma Inc.; 2008 [revised Mar. 2007]. [Accessed 02 Apr. 2019] (online) Available from:
- Negrete R, Molina M, Gutierrez-Aceves J. Preoperative administration of ethamsylate: reduces blood loss associated with percutaneous nepholithotomy? A prospective randomized study. J Urol. 2009;181(4S):625. [Accessed 10 Apr. 2019] (online) Available from:
- ScienceDirect. Mefenamic Acid. [Accessed 02 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Ardor Drugs Pvt Ltd
Address: 418, Payal Complex, Sayajiganj, Baroda.
Address: 418, Payal Complex, Sayajiganj, Baroda.
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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