Metageston Depot 500mg Injection
Prescription Required
Product introduction
Metageston Depot 500mg Injection is a natural female hormone important for regulating ovulation (release of an egg from a woman's ovary) and menstruation. It helps restore menstrual cycles in women whose periods have stopped. It is also used in the treatment of infertility.
Metageston Depot 500mg Injection is generally given by a healthcare professional and should not be self-administered at home. You should use Metageston Depot 500mg Injection as your doctor has advised. Do not use more or less than advised and do not use it for longer than recommended. You may be asked to continue taking this medicine for a period after you get pregnant.
The most common side effects include abdominal cramps, back pain, breast tenderness, hypotension and dizziness, hypercoagulant state, and vaginal bleeding. Your doctor may suggest ways to reduce or prevent these. Occasionally, it may cause a severe allergic reaction requiring urgent medical attention.
Inform your doctor if you have a history of breast cancer, unusual vaginal bleeding, or liver, kidney, or heart disease. Inform your doctor about all other medicines that you are taking as they may affect, or be affected by, this medicine. You will probably have several tests both before and during treatment with this medicine. Metageston Depot 500mg Injection can alter your thinking or reactions and you may feel very tired so be careful while driving or doing anything that requires you to be alert.
Metageston Depot 500mg Injection is generally given by a healthcare professional and should not be self-administered at home. You should use Metageston Depot 500mg Injection as your doctor has advised. Do not use more or less than advised and do not use it for longer than recommended. You may be asked to continue taking this medicine for a period after you get pregnant.
The most common side effects include abdominal cramps, back pain, breast tenderness, hypotension and dizziness, hypercoagulant state, and vaginal bleeding. Your doctor may suggest ways to reduce or prevent these. Occasionally, it may cause a severe allergic reaction requiring urgent medical attention.
Inform your doctor if you have a history of breast cancer, unusual vaginal bleeding, or liver, kidney, or heart disease. Inform your doctor about all other medicines that you are taking as they may affect, or be affected by, this medicine. You will probably have several tests both before and during treatment with this medicine. Metageston Depot 500mg Injection can alter your thinking or reactions and you may feel very tired so be careful while driving or doing anything that requires you to be alert.
Uses of Metageston Depot Injection
Benefits of Metageston Depot Injection
In Hormone replacement therapy
Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Progesterone is one of two important hormones (the other being is estrogen) used in this treatment. However, it may not treat all your symptoms, consult with your doctor. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.
In Treatment of Female infertility
Metageston Depot 500mg Injection contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. This medicine helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.
Side effects of Metageston Depot Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Metageston Depot
- Abdominal pain
- Breast tenderness
- Dizziness
- Abdominal cramp
- Back pain
- Hypotension (low blood pressure)
- Vaginal bleeding
How to use Metageston Depot Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Metageston Depot Injection works
Metageston Depot 500mg Injection is a progesterone (female hormone). It helps to establish and maintain pregnancy. It also prevents the increase in thickness of the endometrium (lining of the uterus) caused by estrogen.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Metageston Depot 500mg Injection. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Metageston Depot 500mg Injection is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.
Breast feeding
SAFE IF PRESCRIBED
Metageston Depot 500mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Metageston Depot 500mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Metageston Depot 500mg Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Metageston Depot 500mg Injection in patients with liver disease. Please consult your doctor.
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Quick tips
- Metageston Depot 500mg Injection is a natural progesterone available as a micronized formulation which helps in better absorption of this medicine.
- It is used as a part of hormone replacement therapy generally in combination with an estrogen.
- It may also be used in the treatment of problems related to menstrual periods such as amenorrhea (absence of periods).
- It also helps in the maintenance of pregnancy in women who are at higher risk of miscarriage.
- It may cause sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
Fact Box
Chemical Class
Progesterone Derivative
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Natural Progesterone
Interaction with drugs
Taking Metageston Depot with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
If used together, Darunavir may affect blood levels of Progesterone (Natural Micronized).
It is recommended to use barrier methods (like condoms), IUDs, or a depot for contracepti
Concurrent use may increase the risk of formation of blood clots.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observatio
Progesterone (Natural Micronized) is not recommended in individuals with known, suspected, or history of breast cancer. Progesterone (Natural Micronized) may oppose anticancer effe
Progesterone (Natural Micronized) may reduce the efficacy of Letrozole.
Do not consume Letrozole with Progesterone (Natural Micronized) if you have or had breast cancer. If essent
Mycophenolate mofetil may reduce the efficacy of Progesterone (Natural Micronized).
Effective contraception must be used before, during, and for at least 6 weeks after stopping My
Patient concerns
User feedback
What are you using Metageston Depot Injection for?
Hormone repla*
100%
*Hormone replacement therapy
FAQs
What is Metageston Depot 500mg Injection and what is it used for?
Metageston Depot 500mg Injection contains progesterone, which is a natural female sex hormone. It is used to treat menstrual and pregnancy-related issues that are caused due to hormonal imbalance. It is also prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus).
How and in what dose should I take Metageston Depot 500mg Injection?
Metageston Depot 500mg Injection is given as an injection into the muscle, by a doctor or nurse only. The dose and duration are decided by your doctor, depending on your exact medical condition. Follow your doctor’s instructions carefully to get the maximum benefit from Metageston Depot 500mg Injection.
What are the common side effects which I can experience while taking Metageston Depot 500mg Injection?
The common side effects associated with Metageston Depot 500mg Injection are local injection site reactions (redness, pain, or swelling), nausea, vaginal discharge, weight changes, jaundice, mental depression, and fever. If any of these side effects bother you, please consult with your doctor.
Does Metageston Depot 500mg Injection cause weight gain?
Yes, the use of Metageston Depot 500mg Injection may cause weight gain. The weight gain may be due to water retention and may not be a serious sign. However, contact your doctor in case your weight gain is worrying you.
How is Metageston Depot 500mg Injection beneficial for fertility and pregnancy?
Metageston Depot 500mg Injection is a crucial hormone for fertility. It is the hormone secreted by the ovaries that helps prepare the uterus for pregnancy and maintain it. This is given as a medicine in cases of infertility to support the uterus in preparing itself for the pregnancy and to prevent abortions in some cases. It is also used to prevent premature labor.
Is Metageston Depot 500mg Injection effective?
Metageston Depot 500mg Injection is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Metageston Depot 500mg Injection too early, the symptoms may return or worsen.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.
- Progesterone. Lodi, Italy: IBSA Farmaceutici Italia Srl; 2013. [Accessed 21 Jun. 2019] (online) Available from:
- Apgar S, Greenberg G. Using Progestins in Clinical Practice. Am Fam Physician. 2000;62(8):1839-46. [Accessed 03 Apr. 2019] (online) Available from:
- Cable JK, Grider MH. Physiology, Progesterone. [Updated 2023 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 [Accessed 25 Jul. 2023] (online) Available from:
Marketer details
Name: Perk Pharmaceuticals Ltd
Address: Perk Pharmaceuticals Limited, A-7, Industrial Estate, Partapur, Meerut-250103, Uttar Pradesh, India
Country of origin: India
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