Metnate 5mg Tablet
Prescription Required
Product introduction
Metnate 5mg Tablet is a medicine used in the treatment of Alzheimer's disease. It helps to slow down the progression of moderate to severe Alzheimer's disease by improving memory and thinking. This medicine works by blocking a chemical messenger involved in the transmission of nerve signals.
Metnate 5mg Tablet maybe taken with or without food. However, it is advised to take it at the same time each day to maintain a consistent level of medicine in the blood. If you missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor.
The most common side effects of this medicine are dizziness, headache, confusion, and constipation. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.
Before taking this medicine, inform the doctor if you have a history of seizures, kidney disease, heart disease, or liver disease. Let your doctor also know if you are taking any other medicines for any medical conditions. Pregnant and breastfeeding women should consult their doctors before taking this medicine.
Uses of Metnate Tablet
Benefits of Metnate Tablet
In Alzheimer's disease
Metnate 5mg Tablet improves learning, memory and information processing (cognitive function) in people with moderate to severe Alzheimer's disease. These problems in memory and thinking may start interfering with daily activities and worsen your condition. This medicine will help in managing Alzheimer’s disease effectively. It will make it easier for you to carry out your daily activities and improve your quality of life. Do not stop taking it unless advised by the doctor. It can take several weeks for your symptoms to improve; so keep using the medicine even if you do not think it is working.
Side effects of Metnate Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Metnate
- Dizziness
- Headache
- Confusion
- Constipation
How to use Metnate Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metnate 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Metnate Tablet works
Metnate 5mg Tablet is an N-methyl-D-aspartate (NMDA) receptor antagonist. Memory loss in Alzheimer’s disease is due to excessive production of glutamate (chemical messenger) in the brain which is mediated by NMDA receptors. Metnate 5mg Tablet works by preventing the action of NMDA receptors and regulates the production of glutamate. involved in the transmission of nerve signals. This is how it prevents memory loss in Alzheimer’s disease.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Metnate 5mg Tablet. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Metnate 5mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Metnate 5mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Metnate 5mg Tablet may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Metnate 5mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Metnate 5mg Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Metnate 5mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Metnate 5mg Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Metnate 5mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
Limited information is available on the use of Metnate 5mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
What if you forget to take Metnate Tablet?
If you miss a dose of Metnate 5mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
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Quick tips
- You have been prescribed Metnate 5mg Tablet to treat dementia (memory loss) in patients with Alzheimer's disease.
- It is well tolerated and has lesser side effects as compared to other similar medicines.
- Be cautious while driving or doing anything that requires concentration until you know how Metnate 5mg Tablet affects you.
- Inform your doctor if you have a history of seizures, kidney disease, heart disease, or liver disease.
- Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
Fact Box
Chemical Class
Amantadine Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
NMDA inhibitors- Alzheimer's disease
Patient concerns
FAQs
Does Metnate 5mg Tablet have abuse potential?
No, Metnate 5mg Tablet does not have abuse potential. On the contrary, it may prevent excess use of addictive drugs such as morphine or ethanol.
When and how Metnate 5mg Tablet should be taken?
Metnate 5mg Tablet should be taken orally once a day. To benefit from your medicine you should take it regularly every day at the same time of the day. The tablets should be swallowed with some water. The tablets can be taken with or without food.
How long does it take for Metnate 5mg Tablet to start working?
For Metnate 5mg Tablet to start working and show its full benefits, it may require between 3 and 8 hours. The doctor may require a follow-up clinical assessment to check the progress after 4 weeks and then 6 months after the first assessment.
What are the symptoms of overdosage of Metnate 5mg Tablet?
The symptoms which can be observed due to an overdose of Metnate 5mg Tablet include tiredness, weakness, drowsiness, confusion, hallucinations, and/or vomiting. Some may also experience diarrhea, vertigo, agitation, aggression, and walking difficulty.
How does Metnate 5mg Tablet affect a person with dementia?
Metnate 5mg Tablet belongs to a class of medications called N-methyl-D- aspartate (NMDA) receptor antagonists. It works by decreasing abnormal activity in the brain. Metnate 5mg Tablet may improve the ability to think and remember. It may also reduce the deterioration of these abilities in people who have Alzheimer's disease. However, with time the effectiveness of this medicine will reduce and it may not be able to cure Alzheimer's disease or prevent the loss of these abilities.
What is dementia?
Dementia is a syndrome in which there is deterioration in memory, thinking, behavior, and the ability to perform everyday activities. Dementia is one of the major causes of disability and dependency among older people worldwide. Alzheimer disease is the most common form of dementia which contributes to around 60 to 70% of cases.
Can I just stop taking Metnate 5mg Tablet?
No, Metnate 5mg Tablet should not be stopped even if you feel well. This medicine only helps to control the symptoms of Alzheimer's disease but does not cure it. If you need to stop the medication then doctor should be consulted first.
Does Metnate 5mg Tablet make you sleepy?
Yes, Metnate 5mg Tablet may make you sleepy. Metnate 5mg Tablet has minor to moderate influence on the ability to drive and usage of machines. In such cases, outpatients should be warned to take special care.
Can Metnate 5mg Tablet be combined with donepezil?
Yes, Metnate 5mg Tablet can be combined with donepezil, as there will be no increased adverse effects. However, this combination will not cure Alzheimer's, but it can only improve thinking ability, short term memory, and other related symptoms.
What medicines should I avoid while taking Metnate 5mg Tablet?
Metnate 5mg Tablet can interact with several medicines. Taking other medicines along with Metnate 5mg Tablet can either make Metnate 5mg Tablet less effective or increase its side effect. Do not take any medicine without talking to your doctor.
Does Metnate 5mg Tablet have any interaction with cardiac medicines?
Yes, Metnate 5mg Tablet may interfere with the working of hydrochlorothiazide (HCT). It decreases the levels of HCT which will reduce the effectiveness of HCT. Also, procainamide and quinidine may increase levels of Metnate 5mg Tablet which may cause increased toxicity.
Can I stop taking Metnate 5mg Tablet if I feel better?
No, keep using Metnate 5mg Tablet as advised by your doctor, even if you feel well. Stopping Metnate 5mg Tablet can bring back your symptoms of dementia.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Katzung BG. Special Aspect of Geriatric Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1141-42.
- Standaert DG, Roberson ED. Treatment of Central Nervous System Degenerative Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 622.
- Stahl SM, editor. Memantine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 397-400.
- Memantine HCl. Dublin, Ireland: Forest Laboratories Ireland Ltd.; 2003 [revised Oct 2013]. [Accessed 25 Jan. 2019] (online) Available from:
- Memantine hydrochloride [EMC SmPC]. Hatfield, Hertfordshire: Generics UK T/A Mylan; 2013 [revised Jun. 2015]. [Accessed 25 Mar 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation. Memantine. [Accessed 11 Jul. 2023]. (online) Available from:
- Memantine Hydrochloride [Patient Information Leaflet]. Bachupally, India: Dr. Reddy’s Laboratories Limited. [Accessed 11 Jul. 2023]. (online) Available from:
- Memantine hydrochloride [Prescribing Information]. Panchmahal, Gujarat: Alembic Pharmaceuticals Limited (Formulation Division); 2023. [Accessed 11 Jul. 2023]. (online) Available from:
Marketer details
Name: Shatayushi Healthcare Pvt Ltd
Address: arvinda ghosh marg, ramdaspeth, akola, maharashtra 444001
Country of origin: India
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