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MD (Pharmacology), MBBS
Last updated
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Mitozan 2mg Injection

Prescription Required

Product introduction

Mitozan 2mg Injection is used in the treatment of certain kinds of breast and blood cancers. It is usually given alone or in together with certain other medicines as part of combination chemotherapy. It prevents cancer cells from growing, as a result of which they eventually die.

Mitozan 2mg Injection is given as an injection into vein under the supervision of a doctor and should not be self-administered. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include anemia (low number of red blood cells), decreased white blood cell count, increased bleeding tendency, infection, nausea, and vomiting. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools.  This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Benefits of Mitozan Injection

In Non-Hodgkin lymphoma (NHL)

Non-Hodgkin's lymphoma is a cancer of the white blood cells in our body, also called mantle-cell lymphoma. White blood cells are those cells that help us to fight infections. Mitozan 2mg Injection helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and further spread. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.

In Blood cancer

Blood cancer, also called leukemia, is a cancer of the blood-forming tissues that decreases the body's ability to fight infection. Mitozan 2mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Breast cancer

Mitozan 2mg Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Mitozan 2mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

Side effects of Mitozan Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Mitozan

  • Absence of menstrual periods
  • Anemia (low number of red blood cells)
  • Decreased white blood cell count
  • Hair loss
  • Nausea
  • Vomiting

How to use Mitozan Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Mitozan Injection works

Mitozan 2mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Mitozan 2mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Mitozan 2mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Mitozan 2mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Mitozan 2mg Injection may cause side effects which could affect your ability to drive.
Mitozan 2mg Injection can have a minor effect on your ability to drive. This is caused by the possible side effects, such as confusion or feeling tired
Kidney
SAFE IF PRESCRIBED
Mitozan 2mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Mitozan 2mg Injection may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Mitozan 2mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Mitozan 2mg Injection may not be needed in these patients. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Mitozan 2mg Injection
₹359/Injection
Scleroxil 2mg Injection
Intas Pharmaceuticals Ltd
₹461.06/injection
25% costlier
Oncotron 2mg Injection
Sun Pharmaceutical Industries Ltd
₹467/injection
26% costlier

Quick tips

  • Mitozan 2mg Injection is given as an injection into veins under the supervision of a doctor.

Fact Box

Chemical Class
Anthracenedione Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alkaloids-cytotoxic agents

Interaction with drugs

Taking Mitozan with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may increase the risk of opportunistic infections. Do not consume Natalizumab with Mitoxantrone.
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells. Do not consume Mitoxantrone from 1 day before until 1 day after taking Sargramostim. ... More
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells. Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytot... More
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells. Do not consume Mitoxantrone from 14 days before until 24 days after taking Pegfilgras... More
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells. Do not consume Mitoxantrone from 1 day before until 1 day after taking Molgramostim. ... More

Patient concerns

arrow
Non Hodgkin lymphoma of defuss large b cells
Dr. Vijay Sharnangat
Medical Oncology and Hematology
I am very much experienced in treating DLBCL
Symptoms of lymphoma And blood cancer
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Symptoms could be like fever, weight loss, anorexia, lymphadenopathy.
arrow

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1715.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 952.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 932-33.
  4. Mitoxantrone. Rockland, Massachusetts: EMD Serono; 2012. [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Mitoxantrone. [Updated 2018 Oct 31]. [Accessed 18 Feb. 2020] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:External Link
  7. Medscape. Mixantrone. [Accessed 26 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Vhb Life Sciences Inc
Address: 50-AB, Government Industrial Estate, Charkop Naka, Kandivali West , Mumbai - 400067, Maharashtra, India
Country of origin: India

359
Inclusive of all taxes
MRP370  3% OFF
10.0 ml in 1 vial
SOLD OUT

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