Mixtard 50 HM 100IU/ml Penfill (3ml Each) is a combination of two medicines, an intermediate-acting and a short-acting type of insulin. It is used in the treatment of diabetes mellitus (type 1 and 2) to improve blood sugar control both in adults and children. It helps maintain the blood sugar levels in diabetic patients.
Mixtard 50 HM 100IU/ml Penfill (3ml Each) is normally prescribed along with other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. It should be taken 15 minutes before a meal or within 20 minutes after starting a meal. Don’t stop taking it unless your doctor tells you to.
It is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Check your blood sugar levels regularly, keep track of your results and share them with your doctor. This is very important to work out the correct dose of the medicine for you.
The most common side effect of this medicine is low blood sugar levels (hypoglycemia). To prevent this, it's important to always inject the correct dose of medicine only, have regular meals, and monitor your blood sugar levels regularly. Drinking excessive alcohol can also lead to a fall in your blood sugar levels. Other side effects include reactions at the injection site like redness or swelling. Some people gain weight while taking insulin. You may also notice a rash, edema (swelling), or itching while taking this medicine.
Do not use this medicine when you have low blood glucose levels (hypoglycemia). Tell your doctor if you’ve ever had kidney, liver or heart problems before starting treatment. Pregnant or breastfeeding women should also consult their doctor as the dose may need to be changed.
Mixtard 50 HM 100IU/ml Penfill (3ml Each) contains an intermediate-acting and a short-acting type of insulin. Together, they ensure rapid and consistent sugar control that helps control blood sugar levels for an entire day. It is given as an injection and your doctor or nurse will train you on the correct way to inject it. Managing blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.
Side effects of Mixtard Suspension for Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mixtard
Hypoglycemia (low blood glucose level)
Injection site reactions (pain, swelling, redness)
Weight gain
How to use Mixtard Suspension for Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Mixtard Suspension for Injection works
Insulin Isophane has a prolonged duration of action, while human insulin has a fast onset of action. Together, they ensure rapid and consistent sugar control by facilitating reuptake of sugar in muscle and fat cells and suppressing the production of sugar in the liver.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Mixtard 50 HM 100IU/ml Penfill (3ml Each).
Pregnancy
SAFE IF PRESCRIBED
Mixtard 50 HM 100IU/ml Penfill (3ml Each) is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Mixtard 50 HM 100IU/ml Penfill (3ml Each) is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Mixtard 50 HM 100IU/ml Penfill (3ml Each) should be used with caution in patients with kidney disease. Dose adjustment of Mixtard 50 HM 100IU/ml Penfill (3ml Each) may be needed. Please consult your doctor. Regular monitoring of blood glucose levels is recommended for dose adjustment.
Liver
CAUTION
Mixtard 50 HM 100IU/ml Penfill (3ml Each) should be used with caution in patients with liver disease. Dose adjustment of Mixtard 50 HM 100IU/ml Penfill (3ml Each) may be needed. Please consult your doctor.
What if you forget to take Mixtard Suspension for Injection?
If you have missed a dose of Mixtard 50 HM 100IU/ml Penfill (3ml Each), your blood sugar level may become too high (hyperglycemia). Check your blood sugar and then take the next dose accordingly.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
Take it 15 minutes before a meal or within 20 minutes after starting a meal.
Injection below the skin of the abdomen results in faster absorption than other injection sites such as skin of the upper arms, thighs, or buttocks. After injection, the site of injection should not be massaged.
Injection sites must be rotated to prevent hard lumps from developing at one site.
Change to another type or brand of insulin should be done under strict medical supervision as it may require a change in dosage.
Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol or on delaying/skipping a meal. Carry a sugar source with you for immediate relief.
Do not share your insulin device with other people, even if the needle has been changed. You may give other people a serious infection or get a serious infection from them.
Opened vials/cartridges stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator (2°C–8°C).
Fact Box
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Patient concerns
I am moving from Human Mixtard 40 IU/ml injections ( 30:70) to 100 IU/ml Penfill ( same 30:70 ). What should be the unit conversion rate if i am taking 20 units of 40 IU/ml mixtard daily. Please advise.
Sir my glucose level is always increase day by day.i am also takin insulin hm mixtard 30 and hm actrapid Sir plz answer me .what can i do
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET
My father is old diabetic patient as well as heart patient recently he fell down from some little height almost 3 ft height after that when we go for x-ray and also measured his blood sugar levels was very high even not measurable in glucometer he is already on insulin humansulin30/70 30 units and galvus met50/500 in morning and denorm Od 60 1-1/2 tablets in eve and galvus met 50/500. Even today when we measured gave human actrapid 20 unit and after 2 hrs again 20 units and humansulin 30/70 30 unit also. Kindly help He also took alcohol but from last two days he is not using it. It is only today that sugar level rose up to HI level. A local has given some antibiotic and steroid for pain caused by felling down Heart medicines are cardrone-X, carca-CR-20,Telecad-20,
Dr. Ashwin Porwal
Internal Medicine
ask your treating physician to add lantus also along with mixtard
My grandmother is suffering from diabetes since 10 years she has got big wound on foot doctors has suggested removed the leg her sugar levels were 300-400 presently she using human actrapid can I use mixtard wat is the diff between actrapid and mixtard wat should I prefer mixtard or actrapid
Dr. Sanjay Bhatt
Physician
Better to follow your doctors advice as she has very poor control of diabetesFor foot and leg wounds need proper care and management
My wife is taking insulin lantus and human mixtard 50/50 along with Janumet 50/500 and alucobay m25 daily. But her blood sugar always fasting and postprandial between 245 and 265
Dr. Sanjay Bhatt
Physician
Dose adjustment needed in the medicine she is taking if she is not having any diet failure. So confirm about her diet failure and discuss with your doctor
Can I drink alcohol while taking Mixtard 50 HM 100IU/ml Penfill (3ml Each)?
No, it is not safe to drink alcohol while using Mixtard 50 HM 100IU/ml Penfill (3ml Each). Drinking alcohol while using this medicine may lower your blood sugar levels and cause unexpected hypoglycemia.
What are the instructions for storage and disposal of Mixtard 50 HM 100IU/ml Penfill (3ml Each)?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Which is the best area to inject Mixtard 50 HM 100IU/ml Penfill (3ml Each)?
Mixtard 50 HM 100IU/ml Penfill (3ml Each) is to be injected under the skin (subcutaneously). The best areas to give Mixtard 50 HM 100IU/ml Penfill (3ml Each) are your stomach, upper thigh, upper arm or buttocks.
What are the symptoms of high blood sugar?
Symptoms of high blood sugar include frequent urination, increased thirst, fatigue, nausea, vomiting, shortness of breath, stomach pain, fruity breath odor, dry mouth and a fast heartbeat.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
European Medicine Agency. Insulin Isophane/NPH+Human Insulin/Soluble Insulin; 2002 [revised Nov. 2013]. [Accessed 08 Apr. 2019] (online) Available from:
Isophane. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2014 [revised 30 Jul. 2018]. [Accessed 08 Apr. 2019] (online) Available from:
Human Insulin. Gatwick, West Sussex: Novo Nordisk Limited; 2002 [revised Mar. 2018]. [Accessed 08 Apr. 2019] (online) Available from:
Mixtard [Summary of Product Characteristics]. Bagsværd, Denmark; Novo Nordisk A/S; 2021. [Accessed 13 Oct. 2021] (online) Available from:
Humulin [FDA Prescribing Information]. Indianapolis, USA; Lilly USA, LLC.; 2018. [Accessed 13 Oct. 2021] (online) Available from:
Medscape. Insulin Isophane/NPH/ Human Insulin/Soluble Insulin. [Accessed 08 Apr. 2019] (online) Available from:
Human insulin isophane suspension and human insulin injection [Prescribing Information]. Indianapolis, IN: Lilly USA, LLC; 2018. [Accessed 14 Aug. 2024] (online) Available from:
Country of origin: Brazil Expires on or after: April, 2026
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