Nicomone 4mg Tablet is an oral anticoagulant that helps prevent harmful blood clots in the legs, lungs, brain, and heart. It is used for deep vein thrombosis, pulmonary embolism, and stroke prevention.

Nicomone 4mg Tablet should be taken as advised by the doctor. You may take it with or without food but it is better to take it at a fixed time. This medicine should not be stopped abruptly without consulting the doctor. You should take this medicine regularly to get the most benefit, even if you feel fine. It is preventing future harm.

Use of this medicine may increase your risk of bleeding. Let your doctor know immediately if you see a pinpoint rash or blood in your vomits, urine, or stool. If you are going under any surgery or dental treatment, you may need to stop this medicine for some time but only after consulting with your doctor.

Before taking it, you must inform the doctor if you are suffering from any kidney or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.

Uses of Nicomone Tablet

Deep vein thrombosis
Pulmonary embolism
Stroke prevention
Blood clots

Side effects of Nicomone Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nicomone

Hemorrhage

How to use Nicomone Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nicomone 4mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Nicomone Tablet works

Nicomone 4mg Tablet is an oral anticoagulant. It acts by preventing the formation of harmful blood clots. Although it does not dissolve the existing blood clots, it inhibits them from growing larger and causing serious problems.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Nicomone 4mg Tablet.

Pregnancy

UNSAFE

Nicomone 4mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

SAFE IF PRESCRIBED

Nicomone 4mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

SAFE

Nicomone 4mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Nicomone 4mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Nicomone 4mg Tablet may be needed. Please consult your doctor.
Use of Nicomone 4mg Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Nicomone 4mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Nicomone 4mg Tablet may be needed. Please consult your doctor.
Use of Nicomone 4mg Tablet is not recommended in patients with severe liver disease.

What if you forget to take Nicomone Tablet?

If you miss a dose of Nicomone 4mg Tablet, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Nicomone 4mg Tablet

₹5.96/Tablet

Acitrom 4 Tablet

Abbott

₹22.5/tablet

278% costlier

Artiflo 4mg Tablet

Zuventus Healthcare Ltd

₹17/tablet

185% costlier

Acenomac 4mg Tablet

Macleods Pharmaceuticals Pvt Ltd

₹12.1/tablet

103% costlier

Nicoz 4mg Tablet

Ajanta Pharma Ltd

₹5.06/tablet

15% cheaper

Acethromb 4mg Tablet

Suvik Hitek Pvt Ltd

₹6.15/tablet

3% costlier

View all substitutes

Quick tips

Avoid making sudden major changes to your diet during treatment with this medicine.
Nicomone 4mg Tablet increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
Do not consume alcohol while taking Nicomone 4mg Tablet as this may increase its side effects.
If you are going to have a surgery or dental treatment, you may be asked to stop taking Nicomone 4mg Tablet temporarily.
Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.
You have been prescribed Nicomone 4mg Tablet to help prevent blood clots.
For best results, take it at the same time every day.
Your doctor may get regular blood tests done to make sure Nicomone 4mg Tablet is working properly.
Nicomone 4mg Tablet increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
Avoid making sudden major changes to your diet during treatment with this medicine.
If you are going to have a surgery or dental treatment, you may be asked to stop taking Nicomone 4mg Tablet temporarily.
Do not consume alcohol while taking Nicomone 4mg Tablet as this may increase its side effects.
Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.

Fact Box

Chemical Class

4-hydroxycoumarin Derivative

Habit Forming

Therapeutic Class

BLOOD RELATED

Action Class

Vitamin K Antagonists

Interaction with drugs

Taking Nicomone with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Axitinib (Oral Route) Life-threatening

Concurrent use may increase the risk of bleeding. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Your doctor may frequently monitor yo... More

Phenytoin (Oral Route) Severe

Concurrent use may increase the risk of severe bleeding. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Cabozantinib (Oral Route) Severe

Concurrent use may increase the risk of bleeding. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Your doctor may frequently monitor yo... More

Dasatinib (Oral Route) Severe

Concurrent use may increase the risk of bleeding. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Your doctor may frequently monitor yo... More

Cilostazol (Oral Route) Severe

Concurrent use may increase the risk of bleeding. Do not consume Acenocoumarol with Cilostazol. If concurrent use is essential, watch out for bleeding and consult your doctor imme... More

View all drug interactions

Patient concerns

Deep vein thrombosis , swelling nd painful in both leg.

Dr. Sunil Sekhri

Diabetology

You need to take a surgical consultation

Looking for a specialist in Deep vein thrombosis preferably in Kochi

Dr. Nabajit Talukdar

Cardiology

See a vascular surgeon

FAQs

How long do I need to take Nicomone 4mg Tablet?

You should continue taking Nicomone 4mg Tablet for as long as recommended by your doctor. Depending upon the condition you are being treated for, you may have to take it for several months or years or maybe for the rest of your life.

What should I avoid while taking Nicomone 4mg Tablet?

You should avoid alcohol while taking Nicomone 4mg Tablet as alcohol may interfere with working of Nicomone 4mg Tablet. In addition to that, avoid cranberry juice or other cranberry products as there may be a risk of enhanced blood thinning. Avoid breastfeeding or getting pregnant as it may harm your child.

Do I need to stop Nicomone 4mg Tablet if I have to undergo a surgery?

Depending on the type of surgery that is to be performed, your doctor will tell you whether to continue or stop Nicomone 4mg Tablet. It will be decided by your doctor after weighing the risks and benefits of discontinuing Nicomone 4mg Tablet.

Is Nicomone 4mg Tablet same as warfarin?

Both Nicomone 4mg Tablet and warfarin are blood thinners, but they have some differences. Warfarin has a more stable blood thinning effect.

How long does it take for Nicomone 4mg Tablet to start working?

It takes a little longer for Nicomone 4mg Tablet to start working. On an average, it may take 2-3 days for Nicomone 4mg Tablet to show its blood-thinning effect. For these 2-3 days, heparin may be used and then discontinued.

What if I forget to take a dose?

If you forget to take a dose of Nicomone 4mg Tablet, take it as soon as you remember. However, if it is time for your next dose then skip the missed dose. Do not double the dose and continue your normal schedule. Keep a diary or set a reminder, so that you do not forget it often.

What monitoring is required while taking Nicomone 4mg Tablet?

The bleeding times should be carefully monitored from 2nd or 3rd dose of Nicomone 4mg Tablet and till the clotting status is stabilized. Thereafter, the bleeding time can be monitored monthly. This frequency may be more in elderly.

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Related lab tests

Activated Partial Thromboplastin Time

Platelet Count

Prothrombin Time

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 865-71
Acenocoumarol. Luxembourg: Merus Labs Luxco II S.à R.L.; 1972 [revised 08 Oct. 2015]. (online) Available from:
Castellano JM, Narayan RL, Vaishnava P, et al. Anticoagulation during pregnancy in patients with a prosthetic heart valve. Nat Rev Cardiol. 2012;9(7):415-24. [Accessed 14 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Acenocoumarol. [Updated 2020 Jan 20]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Acenocoumarol. [Accessed 14 Mar. 2019] (online) Available from:
Abbott. Acenocoumarol [Product Information]. [Accessed 09 Jun, 2023] (online) Available from:

Marketer details

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Country of origin: India

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