Nitrothem 5mg Injection
Prescription Required
Product introduction
Nitrothem 5mg Injection is used to treat and prevent heart-related chest pain (angina) and hypertension (high blood pressure) during surgery. This medicine works by relaxing and widening blood vessels so blood can flow more easily to the heart. It has a very short-lived effect.
Nitrothem 5mg Injection is given as an injection under the supervision of a doctor with careful blood pressure monitoring. This is given as a continuous infusion into a vein and should not be stopped abruptly. It should not be mixed with any other medication of any kind.
The most common side effect of Nitrothem 5mg Injection is a headache which may be severe. This can sometimes be helped by drinking plenty of fluids and avoiding alcohol. You may also experience lightheadedness, which could increase your risk of having a fall. There are other, rarer side effects, some of them serious. Ask your doctor and read the leaflet which comes with the medicine to make sure you are keeping safe.
Do not use Nitrothem 5mg Injection if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), or erectile dysfunction; or if you have anemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. It is best not to drink alcohol with this medicine as it increases some of the side effects. If you are affected by dizziness, avoid driving. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine.
Nitrothem 5mg Injection is given as an injection under the supervision of a doctor with careful blood pressure monitoring. This is given as a continuous infusion into a vein and should not be stopped abruptly. It should not be mixed with any other medication of any kind.
The most common side effect of Nitrothem 5mg Injection is a headache which may be severe. This can sometimes be helped by drinking plenty of fluids and avoiding alcohol. You may also experience lightheadedness, which could increase your risk of having a fall. There are other, rarer side effects, some of them serious. Ask your doctor and read the leaflet which comes with the medicine to make sure you are keeping safe.
Do not use Nitrothem 5mg Injection if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), or erectile dysfunction; or if you have anemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. It is best not to drink alcohol with this medicine as it increases some of the side effects. If you are affected by dizziness, avoid driving. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine.
Uses of Nitrothem Injection
Benefits of Nitrothem Injection
In Treatment of Hypertension (high blood pressure)
Nitrothem 5mg Injection is used to treat hypertension in hypertensive emergencies. It rapidly dilates (widens) the blood vessels. This rapid vasodilation helps reduce blood pressure levels, relieving the strain on the heart and improving blood flow to vital organs. It is typically used in critical situations where immediate blood pressure reduction is necessary, such as severe high blood pressure that can lead to organ damage or other life-threatening complications.
Side effects of Nitrothem Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nitrothem
- Blurred vision
- Decreased blood pressure
- Dizziness
- Headache
- Increased heart rate
- Lightheadedness
- Paresthesia (tingling or pricking sensation)
How to use Nitrothem Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Nitrothem Injection works
Nitrothem 5mg Injection is a nitrate. It works by improving blood supply to heart and relaxing the blood vessels which decreases the oxygen demand of the heart and reduces its workload, thereby preventing/treating attacks of angina (chest pain). Relaxation of blood vessels lowers blood pressure.
Safety advice
Alcohol
UNSAFE
Consuming alcohol while taking Nitrothem 5mg Injection may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
SAFE IF PRESCRIBED
Nitrothem 5mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Nitrothem 5mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Nitrothem 5mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Nitrothem 5mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Nitrothem 5mg Injection may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Nitrothem 5mg Injection in patients with liver disease. Please consult your doctor.
What if you forget to take Nitrothem Injection?
If you miss a dose of Nitrothem 5mg Injection, consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Nitrothem 5mg Injection
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Quick tips
- It is given via a drip into a vein under the supervision of a doctor.
- It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
- Nitrothem 5mg Injection may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
- Do not consume alcohol while taking Nitrothem 5mg Injection as it may cause increased dizziness.
- Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nitrothem 5mg Injection as it may cause low blood pressure.
- You have been prescribed Nitrothem 5mg Injection for the prevention and treatment of heart-related chest pain (angina).
- Eat healthy (low-fat, high-fiber, low-sodium diet), quit smoking, increase your physical activity, watch your weight and reduce stress.
- Nitrothem 5mg Injection may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
- Do not consume alcohol while taking Nitrothem 5mg Injection as it may cause increased dizziness.
- It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
- You may develop tolerance to Nitrothem 5mg Injection with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
- Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nitrothem 5mg Injection as it may cause low blood pressure.
Fact Box
Chemical Class
Nitrates {Short acting}
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Nitric Oxide (NO) Donors
Interaction with drugs
Taking Nitrothem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may cause a severe drop in blood pressure that may lead to a heart attack.
Do not consume Sildenafil with Nitroglycerin. If Sildenafil is essential, ensure a gap o
Concomitant use may cause a severe drop in blood pressure that may lead to a heart attack.
Do not consume Sildenafil with Nitroglycerin. If Sildenafil is essential, ensure a gap o
Concomitant use may cause a severe drop in blood pressure that may lead to a heart attack.
Do not consume Sildenafil with Nitroglycerin. If Sildenafil is essential, ensure a gap o
Concomitant use may cause a severe drop in blood pressure that may lead to a heart attack.
Do not consume Tadalafil with Nitroglycerin. If Tadalafil is essential, ensure a gap of
Concomitant use may cause a severe drop in blood pressure that may lead to a heart attack.
Do not consume Sildenafil with Nitroglycerin. If Sildenafil is essential, ensure a gap o
Patient concerns
FAQs
Does the effect of Nitrothem 5mg Injection wear off after sometime?
Yes, excessive use of Nitrothem 5mg Injection may cause tolerance which means that Nitrothem 5mg Injection may lose its effectiveness on you. Therefore, doctors usually prescribe the smallest dose required for effective relief of acute angina attacks. Also, it is usually prescribed in morning and afternoon doses to give nitrate-free interval. Take it strictly as per the dosing interval prescribed by your doctor to prevent tolerance and maintain the effectiveness of Nitrothem 5mg Injection.
What does too much Nitrothem 5mg Injection do?
Excess Nitrothem 5mg Injection may result in low blood pressure, sweating, nausea, vomiting, headache, weak and fast pulse. It may also cause weakness, lightheadedness on standing and the patient might even faint. The patient will require emergency medical treatment in such a case.
Does Nitrothem 5mg Injection stop heart attacks?
Nitrothem 5mg Injection is prescribed to prevent attacks of heart-related chest pain (angina) in patients with coronary artery disease. In this disease, the blood vessels (coronary arteries) which supply blood to the heart become narrow because of which the heart has to work harder to get enough oxygen. Nitrothem 5mg Injection prevents angina by relaxing the blood vessels so that the heart does not have to work very hard. Also, relaxation of coronary arteries increases the oxygen supply to the heart.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 747-55.
- Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 191, 195-97.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 986-88.
- Nitroglycerin [FDA Label]. Deerfield, IL: Baxter Healthcare Corporation; 2014. [Accessed 15 Nov. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Nitroglycerin. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
- Nitroglycerin Injection [Product Information]. [Accessed 02 Aug. 2023] (online) Available from:
- Nitroglycerin Injection [FDA Label]. Shirley, NY: American Regent Laboratories Inc.; 2022. [Accessed 02 Aug. 2023] (online) Available from:
Marketer details
Name: Themis Medicare Ltd
Address: 11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.
Country of origin: India
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