Nivolumab 40mg Injection
Prescription Required
Product introduction
Nivolumab 40mg Injection is used in the treatment of non-small cell lung cancer, kidney cancer, head and neck cancer, melanoma, Hodgkin's disease, and liver cancer.
Nivolumab 40mg Injection is given as an infusion into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some common side effects of this medicine include rash, weakness, headache, and fever. Some serious side effects which may occur during infusion include chills or shaking, itching, rash, flushing, difficulty breathing and dizziness. Hence, your doctor will check you timely after infusion for allergic reaction.
Before taking it, tell your doctor if have lung disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Nivolumab 40mg Injection is given as an infusion into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some common side effects of this medicine include rash, weakness, headache, and fever. Some serious side effects which may occur during infusion include chills or shaking, itching, rash, flushing, difficulty breathing and dizziness. Hence, your doctor will check you timely after infusion for allergic reaction.
Before taking it, tell your doctor if have lung disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Nivolumab Injection
Benefits of Nivolumab Injection
In Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Nivolumab 40mg Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Kidney cancer
Nivolumab 40mg Injection is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover.
In Head and neck cancer
Head and neck cancer includes cancer of the mouth, nose, sinuses or throat. Nivolumab 40mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.
In Melanoma
Melanoma is a type of skin cancer that develops in melanocytes, the cells that produce the pigment called melanin. Melanin is the pigment that gives the skin its color. Melanoma is the most deadly and aggressive kind of skin cancer. Nivolumab 40mg Injection sticks to the genetic code, called DNA,of the cancer cells and kills them . It also prevents their growth and further spread. This helps to treat the cancer.
In Hodgkin’s disease
Hodgkin’s disease is a type of lymphoma, which is a blood cancer that starts in the lymphatic system. The lymphatic system helps the immune system get rid of waste and fight infections. Nivolumab 40mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Follow your doctor’s instructions carefully.
In Liver cancer
Liver cancer is the cancer that develops in the cells of the liver called hepatocytes. There may be no symptoms present in the early stages of the cancer but as the disease advances to later stages symptoms such as weight loss, stomach pain, vomiting and yellowed skin. Nivolumab 40mg Injection kills the cancer cells and prevents further growth and spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and do not drink alcohol or smoke. Alcohol intake or smoking can worsen your condition and hinder your recovery.
Side effects of Nivolumab Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nivolumab
- Rash
- Weakness
- Headache
- Fever
- Musculoskeletal (bone, muscle or joint) pain
- Back pain
- Stomach pain
- Nausea
- Itching
- Constipation
- Diarrhea
- Upper respiratory tract infection
- Decreased appetite
- Breathlessness
- Cough
How to use Nivolumab Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Nivolumab Injection works
Nivolumab 40mg Injection is an anti-cancer medication. It works by blocking a protein (PD-1) on the surface of certain immune cells called T-cells. This action activates the T-cells to locate and kill cancer cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Nivolumab 40mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Nivolumab 40mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Nivolumab 40mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Nivolumab 40mg Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Nivolumab 40mg Injection is safe to use in patients with kidney disease. No dose adjustment of Nivolumab 40mg Injection is recommended.
Liver
SAFE IF PRESCRIBED
Nivolumab 40mg Injection is safe to use in patients with liver disease. No dose adjustment of Nivolumab 40mg Injection is recommended.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Nivolumab 40mg Injection
₹37412/Injection
Opdyta 40mg Injection
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Opdyta (PAP) 40mg Injection
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Quick tips
- Nivolumab 40mg Injection is given as in injection or infusion under the supervision of a doctor only.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- Your doctor may get regular blood tests done to monitor your blood cell count (CBC), electrolyte levels, liver and kidney function.
- Inform your doctor if you experience fever, chills, rash and shortness of breath during the treatment.
Fact Box
Chemical Class
Monoclonal antibody (mAb)
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Programmed Cell Death 1 (PD-1) Checkpoint Inhibitors
Interaction with drugs
Taking Nivolumab with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may increase the risk of infections.
Do not use Nivolumab with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).
Concurrent use may increase the risk of infections.
Do not use Nivolumab with Purified Vi Polysaccharide Typhoid Vaccine.
Concurrent use may increase the risk of infections.
Do not use Nivolumab with Cholera Vaccine (Inactivated).
Methylprednisolone may interfere with the effects of Nivolumab.
Do not consume Nivolumab with Methylprednisolone. If concurrent use is essential, please consult your doctor.
Betamethasone may interfere with the effects of Nivolumab.
Do not consume Nivolumab with Betamethasone. If concurrent use is essential, please consult your doctor.
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Nivolumab. Nexus Court, MULGRAVE: Bristol-Myers Squibb Australia Pty Ltd; 2016. [Accessed 26 Mar. 2019] (online) Available from:
- Medscape. Nivolumab. [Accessed 26 Mar. 2019] (online) Available from:
- Nivolumab. Uxbridge, Middlesex: Bristol-Myers Squibb Pharmaceuticals limited; 2015 [revised 1 Feb. 2019]. [Accessed 26 Mar. 2019] (online) Available from:
Marketer details
Name: Oro Pharmaceuticals Pvt Ltd
Address: plot no - 53, bahar bisinabhar, link road, p.o - arunodaya market cuttack odisha 753012 india
Country of origin: India
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₹37412
Inclusive of all taxes
MRP₹39800 6% OFF
1.0 Injection in 1 vial
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