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Nubimax 250mg Injection

Bivalirudin (250mg)
Genuine
Authenticity Assured
Prescription
required
Nubimax 250mg Injection belongs to a group of medicines known as an anticoagulant or blood thinner. It helps prevent and treat blood clots. It is used to reduce the risk of stroke and heart attack. It also prevents and treats clot formation in the veins of your legs, lungs, brain, and heart.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)
₹7694 MRP ₹8437.59% off 
Gurgaon
 
 
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Nubimax 250mg Injection is currently sold out
Same composition alternative:
Bivasave 250mg Injection
₹7746₹8494.64
Available alternative from Abbott
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Nubimax 250mg Injection
Nubimax 250mg Injection
vial of 1 Injection
₹7694
₹8437.5
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Same composition
Bivasave 250mg Injection
Bivasave 250mg Injection
vial of 1 Injection
Bivalirudin (250mg)
by Abbott
Get by Wed, 13 May
₹7746
₹6746.0 per unit

₹6746

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General Information

Contains

Bivalirudin (250mg)

Marketer

Emcure Pharmaceuticals Ltd

Storage

Store below 30°C
The content is shown in English
Nubimax 250mg Injection image
Nubimax 250mg Injection image

Product introduction

Nubimax 250mg Injection is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It is given as a drip into a vein by a doctor or a nurse. You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, exercising regularly, and losing weight if you need to.

The most common side effects of this medicine are headache, low platelet level, and fever. It may also make you bleed more easily than normal, for example, having nosebleeds or bruising. You should be extra careful while shaving, cutting nails, or using sharp objects during treatment with this medicine.

This medicine may not be suitable for everyone and should be used with caution. Inform your doctor, if you have severe kidney or liver problems. Do not take this medicine if you are currently bleeding or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.

Uses of Nubimax Injection

  • Treatment and prevention of Blood clots

Benefits of Nubimax Injection

Treatment and prevention of Blood clots
Nubimax 250mg Injection is a type of medicine known as an anticoagulant. Although it does not “dissolve” blood clots, it can prevent them from getting bigger so your body can dissolve them over time. It will also prevent new ones from forming. It works by blocking a substance in the body which is involved in blood clotting. This keeps your blood flowing freely around your body and makes it less likely that a clot will form inside a blood vessel.

This can help prevent or reduce damage caused by stroke, clots in your lungs (pulmonary embolism) or other blood vessels (thrombosis). It can also make it less likely that parts of a clot will break off and travel to other parts of the body. It is given as an infusion (drip) into a vein under the supervision of a doctor. You should make appropriate lifestyle changes to help this medicine be effective.

Side effects of Nubimax Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nubimax
  • Bleeding
  • Low blood platelets
  • Headache
  • Fever

How to use Nubimax Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Nubimax Injection works

Nubimax 250mg Injection is an anticoagulant that prevents the formation of harmful blood clots.

All substitutes for Nubimax 250mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Bivasave 250mg Injection

by Abbott
₹8494.64/injection
1% costlier
<h3 class=bodySemiBold>Bivasave 250mg Injection</h3>

Bivastat 250mg Injection

by Cipla Ltd
₹6496.88/injection
23% cheaper
<h3 class=bodySemiBold>Bivastat 250mg Injection</h3>

Gennomax 250mg Injection

by Emcure Pharmaceuticals Ltd
₹5493.75/injection
35% cheaper
<h3 class=bodySemiBold>Gennomax 250mg Injection</h3>

Ngmine Injection

by Samarth Life Sciences Pvt Ltd
₹8766.19/injection
4% costlier
<h3 class=bodySemiBold>Ngmine Injection</h3>

Bivamax 250mg Injection

by Lupin Ltd
₹5089.59/injection
40% cheaper
<h3 class=bodySemiBold>Bivamax 250mg Injection</h3>

Quick tips

  • It is a hospital only medicine. It is given by your nurse or doctor as an infusion (drip) into a vein.
  • Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
  • Inform your doctor if you are taking other blood thinners or medicines to prevent blood clots. 

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Nubimax 250mg Injection
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Nubimax 250mg Injection is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Nubimax 250mg Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

NOT RELEVANT
Not relevant, as Nubimax 250mg Injection is intended for use in hospitalized patients.
Kidney

Kidney

CAUTION
Nubimax 250mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Nubimax 250mg Injection is not recommended in patients with severe kidney disease and patients undergoing dialysis.
Liver

Liver

SAFE IF PRESCRIBED
Nubimax 250mg Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Nubimax with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Apixaban (Oral Route)

Do not consume Apixaban with Bivalirudin. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Bivalirudin may increase the effect of Apixaban.
Moderate

Rivaroxaban (Oral Route)

Do not consume Rivaroxaban with Bivalirudin. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. They may adjust the dose of Bivalirudin accordingly.
Moderate

Dabigatran Etexilate (Oral Route)

Do not consume Dabigatran Etexilate with Bivalirudin. If concurrent use is essential, please consult your doctor.
Moderate

Dasatinib (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Your doctor may change the treatment accordingly.
Moderate

Abciximab (Injection Route)

If concurrent use is essential, your doctor may monitor your blood clotting time and efficiency.

Frequently asked questions

Unlike other anticoagulants, Nubimax 250mg Injection usually does not affect the functioning of the liver. But long-term use of Nubimax 250mg Injection may increase the chances of mild liver injury in patients with elevated liver enzymes. However, the overall chances of developing any such problem are lower than other anticoagulants. It is advised that you inform your doctor if you have a history of liver disease before starting this medicine.
Taking alcohol while taking Nubimax 250mg Injection can increase the blood-thinning effect of this medicine, thereby increasing the chance of bleeding. Regular intake of alcohol can lead to a gastric ulcer which might again cause bleeding. So, it is better to avoid alcohol while you are taking this medicine. Do consult your doctor if any such episode of bleeding occurs.
Nubimax 250mg Injection should be stored at room temperature between 20º-25º C (68º-77°F) in the original carton it came in. Do not freeze. Store the medicine at a dry place and protect the medicine from moisture and light.
Nubimax 250mg Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Nubimax 250mg Injection. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.
People experiencing any unusual bleeding or people allergic to Nubimax 250mg Injection should not take it. Nubimax 250mg Injection should also be avoided by people with artificial (prosthetic) heart valves. Therefore, inform your doctor if you have ever had or plan to have a valve in your heart replaced. Also, the use of this medicine is not recommended in patients with severe kidney disease.
Yes, Nubimax 250mg Injection may increase the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
No, Nubimax 250mg Injection does not usually cause hair loss. However, there do exist some rare reports of hair loss associated with Nubimax 250mg Injection. Consult your doctor if you face hair loss while taking Nubimax 250mg Injection to rule out any other causes of hair loss.

Fact Box

Chemical Class

Polypeptides

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Direct thrombin inhibitor- parenteral

References

  1. Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 859-60.
  2. Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 594.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 147-48.
  4. Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 371-73.
  5. Bivalirudin. Parsippany, New Jersey: The Medicines Company; 2000 [revised Mar. 2016]. [Accessed 15 Mar. 2019] (online) Availabble from:
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Bivalirudin. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Emcure Pharmaceuticals Ltd
Address: 255/2, Hinjawadi, Pune - 411057, India / Godown A, Gat No. 408 and 410, Vill: Urse, Tal: Maval, Pune-410 506, Maharashtra, India.

Vendor Details

Country of origin: India

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