





Octaplex 500 IU Injection
Human Prothrombin Complex (500IU)
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Octaplex 500 IU Injection treats or prevents bleeding in people lacking certain clotting factors, such as hemophilia or vitamin K deficiency. It can also be used in emergencies to quickly stop bleeding in patients on anticoagulant therapy, especially before surgery or following an injury.
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 11 Oct 2026 | 01:01 AM (IST)
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 11 Oct 2026 | 01:01 AM (IST)
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Get up to ₹75 cashback on a minimum order value (MOV) of ₹499 and above, valid once per customer.
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General Information
Contains
Human Prothrombin Complex (500IU)
Marketer
Bharat Serums & Vaccines Ltd
Storage
Store below 25°C
The content is shown in English






Product introduction
Octaplex 500 IU Injection is used to aid blood clotting in case of minor wounds when surgical techniques are not possible
Uses of Octaplex Injection
Benefits of Octaplex Injection
Bleeding
Octaplex 500 IU Injection provides essential clotting factors that help the blood to clot more effectively, making it highly beneficial in managing and preventing bleeding. It is particularly valuable for patients who lack certain clotting factors due to conditions like hemophilia or vitamin K deficiency or those on anticoagulant (blood thinner) therapy who experience or are at risk of excessive bleeding. By rapidly replenishing these clotting factors, Octaplex 500 IU Injection can stop or reduce bleeding quickly, making it useful in emergencies, such as before surgeries or after traumatic injuries.
Octaplex 500 IU Injection provides essential clotting factors that help the blood to clot more effectively, making it highly beneficial in managing and preventing bleeding. It is particularly valuable for patients who lack certain clotting factors due to conditions like hemophilia or vitamin K deficiency or those on anticoagulant (blood thinner) therapy who experience or are at risk of excessive bleeding. By rapidly replenishing these clotting factors, Octaplex 500 IU Injection can stop or reduce bleeding quickly, making it useful in emergencies, such as before surgeries or after traumatic injuries.
Side effects of Octaplex Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Octaplex
- Vomiting
- Dizziness
- Hypotension (low blood pressure)
- Anemia (low number of red blood cells)
- Headache
- Nausea
How to use Octaplex Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Octaplex Injection works
Octaplex 500 IU Injection is a medication that helps blood to clot. It raises the levels of certain blood clotting proteins, helping restore the natural balance needed for proper clotting.
Quick tips
- Always stick to the dosage and treatment plan prescribed by your doctor. The exact dose is crucial for achieving the best results and preventing complications.
- Drink plenty of water and rest after receiving Octaplex 500 IU Injection to help your body recover and minimize mild side effects, such as headaches or dizziness.
- To lower the risk of injury or bleeding, avoid strenuous physical activities or contact sports while undergoing treatment with Octaplex 500 IU Injection.
- If you are prone to bleeding or have a bleeding disorder, follow additional precautions suggested by your doctor to avoid excessive bleeding or injury.
- If you have any upcoming procedures, ensure your doctor knows you are receiving Octaplex 500 IU Injection, as this could impact your treatment or surgical approach.
- If bleeding does not improve or you experience new symptoms after treatment, contact your doctor immediately.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Octaplex 500 IU Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Octaplex 500 IU Injection during pregnancy is not available. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Octaplex 500 IU Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving
CONSULT YOUR DOCTOR
It is not known whether Octaplex 500 IU Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of Octaplex 500 IU Injection in patients with kidney disease. Please consult your doctor.

Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of Octaplex 500 IU Injection in patients with liver disease.
Frequently asked questions
Octaplex 500 IU Injection treats or prevents bleeding in people who lack certain blood-clotting factors. This includes people with hemophilia, those who are vitamin K deficient, or individuals on anticoagulant (blood thinner) therapy who require rapid reversal of the medication’s effects. It is especially helpful in emergency bleeding situations or before surgery.
Octaplex 500 IU Injection is administered by a doctor or a nurse, usually as an intravenous (IV) infusion directly into the bloodstream. The doctor carefully determines the dose and administration frequency based on individual needs.
Resting and staying hydrated may help with mild side effects like headache or dizziness. However, seek immediate medical attention if you experience severe symptoms, such as breathing difficulty or a rash.
It is important to inform your doctor about any other medicines you take, especially blood thinners, as Octaplex 500 IU Injection may interact with them. Your doctor will advise you on any necessary adjustments to your medication regimen.
To reduce bleeding risks, avoid strenuous physical activities or contact sports while undergoing treatment with Octaplex 500 IU Injection. Consult your doctor about any other activities you may need to limit.
If you are pregnant or breastfeeding, inform your doctor before starting treatment. The effects of Octaplex 500 IU Injection on pregnancy and breastfeeding are not fully known, and your doctor will consider these factors when determining if Octaplex 500 IU Injection suits you.
People with a history of blood clotting disorders, liver disease, or heart disease should use Octaplex 500 IU Injection with caution, as it may increase the risk of blood clots. Always share your complete medical history with your doctor to ensure Octaplex 500 IU Injection is safe for you.
Contact your doctor immediately if your bleeding does not improve or worsens after treatment. They may need to adjust the dose or explore alternative treatment options.
Fact Box
Chemical Class
Peptides
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Coagulation Factors
References
- Prothrombin complex concentrate, human-lans [Prescribing Information]. Paramus, NJ: Octapharma USA Inc.; 2023. [Accessed 03/11/2024] (online) Available from:
- Prothrombin Complex Concentrate (Human) [Prescribing Information]. Kankakee, IL: CSL Behring LLC; 2023. [Accessed 03/11/2024] (online) Available from: [Accessed 03/11/2024] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Bharat Serums & Vaccines Ltd
Address: 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.
Address: 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.
Vendor Details
Country of origin: Austria
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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