Offzole 200mg/400mg Tablet is a combination medicine that is used to treat diarrhea and dysentery. It prevents the growth of microorganisms to treat the infection.

Offzole 200mg/400mg Tablet is a prescription medicine that is advised to be taken as suggested by the doctor. It should be taken with or without food, but it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as an overdose of it may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The treatment must be completed even if you feel better to ensure a complete recovery.

This medicine may lead to some side effects such as nausea, vomiting, stomach pain, loss of appetite, headache, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must consult your doctor immediately.

Before taking this medicine, you should tell your doctor if you have any problems with your liver or kidneys. Also, tell your doctor if you are on any medication for any health condition. Pregnant or breastfeeding women should also consult with the doctors before taking it. Avoid drinking alcohol as it can cause excessive dizziness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. It is advised to take proper rest during the course of treatment for the medicine to work effectively.

Uses of Offzole Tablet

Benefits of Offzole Tablet

In Treatment of Diarrhea

Diarrhea is an increase in the frequency of bowel movements or loose watery bowel movements. It can most commonly occur due to an infection of the digestive tract. Offzole 200mg/400mg Tablet helps to treat diarrhea that is caused due to bacteria or parasitic worm infections. This medicine can relieve frequent loose motions and also help you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.

In Treatment of Dysentery

Dysentery or amoebic dysentery is a parasitic infection of the intestines that occurs mostly due to intake of contaminated food or water. The symptoms include loose stools (diarrhea), stomach cramps and stomach pain. Offzole 200mg/400mg Tablet helps to treat this infection by killing the infection causing parasites. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.

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Side effects of Offzole Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Offzole

Nausea
Dryness in mouth
Metallic taste
Headache

How to use Offzole Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Offzole 200mg/400mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Offzole Tablet works

Offzole 200mg/400mg Tablet is a combination of two antibiotics: Ofloxacin and Metronidazole. Ofloxacin works by preventing the bacterial cells from dividing and repairing, thereby killing the bacteria. Metronidazole kills parasites and anaerobic bacteria that cause infections by damaging their DNA. Together, they treat your infection effectively.

Safety advice

Alcohol

UNSAFE

Consuming alcohol while taking Offzole 200mg/400mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Pregnancy

CONSULT YOUR DOCTOR

Offzole 200mg/400mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Offzole 200mg/400mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Offzole 200mg/400mg Tablet may cause side effects which could affect your ability to drive.
Offzole 200mg/400mg Tablet may make you feel sleepy, dizzy, confused. You may have hallucinations, fits (convulsions) or temporary eyesight problems (such as blurred or double vision) affecting your ability to drive.

Kidney

CAUTION

Offzole 200mg/400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Offzole 200mg/400mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Offzole 200mg/400mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Offzole 200mg/400mg Tablet may be needed. Please consult your doctor.

What if you forget to take Offzole Tablet?

If you miss a dose of Offzole 200mg/400mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Offzole 200mg/400mg Tablet

₹6.2/Tablet

Oftec-M 200mg/400mg Tablet

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Oyxin M 200mg/400mg Tablet

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₹6.3/tablet

2% costlier

Flo Flox M 200mg/400mg Tablet

Bindlysh Biotec Ltd

₹6.2/tablet

same price

Quick tips

Your doctor has prescribed this combination medicine for the treatment of diarrhea and dysentery.
Diarrhea can cause dehydration. Drink plenty of fluids to help rehydrate you.
Consult your doctor if your diarrhea lasts for more than 48 hours.
Do not use Offzole 200mg/400mg Tablet if you have blood in your stool or if you are severely constipated.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking Offzole 200mg/400mg Tablet as it may irritate your stomach and also cause excessive drowsiness.
Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Patient concerns

Diarrhea and dysentery last 15 days I had taken levofoxcin+ornidazol bd for 5 days along refaximin 400 tab bd for 5 day but it is start again

Dr. Sfurti Mann

Internal Medicine

Get a colonoscopy done for chronic Diarrhea

For diarrhea which antibiotic is good for kids and for dysentery which antibiotic is good for kids?

Dr. Gopal Bansilal Samdani

Paediatrics

There are many underlying causes of Patient?s symptoms. Different cause needs different treatment. Specific treatment cannot be given unless we establish exact underlying cause. Final and perfect diagnosis cannot be done without doing clinical examination of patient. Please consult me or any other Paediatrician. will take detail history and will examine patient in detail. All information will be used to determine exact underlying cause of problem. Depending upon cause will give opinion and prescribe you treatment. At time may ask you relevant investigations if necessary. Patient may need antibiotics and/or other prescription drugs. It is mandatory for the customer to have a prescription for the prescription medicines he/she is procuring. Valid prescription cannot be given without diagnosis and clinical examination. Advice given without doing clinical examination can be imperfect or some time harmful to patient.

Dysentery with sticky white traces

Dr. Gopal Bansilal Samdani

Paediatrics

There are many underlying causes of your symptoms. Different cause needs different treatment. Specific treatment cannot be given unless we establish exact underlying cause. Final and perfect diagnosis cannot be done without doing clinical examination of child. Please consult me or any other Paediatrician. will take detail history and will examine your child in detail. All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment. At time may ask you relevant investigations if necessary. Your child may need antibiotics and/or other prescription drugs. It is mandatory for the customer to have a prescription for the prescription medicines he/she is procuring. Valid prescription/advise cannot be given without diagnosis.

FAQs

What are the instructions for the storage and disposal of Offzole 200mg/400mg Tablet?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Can I take a higher than the recommended dose of Offzole 200mg/400mg Tablet?

No, taking a higher than the recommended dose of Offzole 200mg/400mg Tablet can lead to increased side effects. If you are experiencing increased severity of your symptoms which are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Can the use of Offzole 200mg/400mg Tablet cause metallic taste?

Yes, the use of Offzole 200mg/400mg Tablet can cause a temporary metallic taste. This metallic taste can be reduced by chewing sugar-free gum or mints, brushing teeth after the meals and by staying hydrated.

Are there any specific contraindications associated with the use of Offzole 200mg/400mg Tablet?

The use of Offzole 200mg/400mg Tablet is considered to be harmful for patients with known allergy to ofloxacin or to or any other excipient. It should also be preferably avoided in patients with history of any inflammation of the tendons (tendinitis), or tendon rupture seen with the use of ofloxacin or any other medicine which belongs to the same group (quinolone group) of antimicrobial agents and in patients with some neurological disorder.

Can the use of Offzole 200mg/400mg Tablet cause nausea and vomiting?

Yes, the use of Offzole 200mg/400mg Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medicine. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicine without speaking to a doctor.

Can the use of Offzole 200mg/400mg Tablet cause dryness in the mouth?

Yes, the use of Offzole 200mg/400mg Tablet can cause dry mouth. If you experience dry mouth drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry.

Can I take Offzole 200mg/400mg Tablet while I am breastfeeding?

Offzole 200mg/400mg Tablet should be used with caution in nursing mothers as it can lead to serious side effects. You should always consult your doctor before taking Offzole 200mg/400mg Tablet.

Are there any specific conditions in which Offzole 200mg/400mg Tablet should not to be taken?

The use of Offzole 200mg/400mg Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine.

What if I don't get better after using Offzole 200mg/400mg Tablet?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

Can I stop taking Offzole 200mg/400mg Tablet when I feel better?

No, do not stop taking Offzole 200mg/400mg Tablet and complete the full course of treatment even if you are feeling better. Your symptoms may improve before the infection is completely cured.

What if I miss my dose?

Take Offzole 200mg/400mg Tablet as soon as you remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

MedIndia. Metronidazole + Ofloxacin. [Accessed 15 Apr. 2019] (online) Available from:
Ofloxacin. Raritan, New Jersey: Ortho-McNeil-Janssen Pharmaceuticals, Inc.; 2008. [Accessed 15 Apr. 2019] (online) Available from:
Metronidazole. New York, New York: Pfizer; 2010. [Accessed 15 Apr. 2019] (online) Availabel from:
Ofloxacin. Potters Bar Hertfordshire: Generics [UK] Limited; 2002 [revised Mar. 2016]. [Accessed 15 Apr. 2019] (online) Available from:

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Address: 128/5, Swiss House, Vishwas Nagar, Delhi 110032 Delhi, India

Country of origin: India

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