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Otelast 30mg Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Otelast 30mg Tablet is used in the treatment of moderate to severe plaque psoriasis, which is a type of skin condition. This medicine is used when regular treatments do not work or cannot be used due to side effects or poor response.
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Otelast 30mg Tablet is currently sold out
Same composition alternative:
Aprezo 30mg Tablet
₹308₹333.7
36% cheaper alternative available from Glenmark Pharmaceuticals
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Otelast 30mg Tablet
Otelast 30mg Tablet
strip of 10 tablets
₹411
₹450
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Same composition
Aprezo 30mg Tablet
Aprezo 30mg Tablet
strip of 10 tablets
Apremilast (30mg)
by Glenmark Pharmaceuticals Ltd
Get in 30 mins
₹308
₹26.2 per tablet

₹262

order for
₹1200

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General Information

Contains

Apremilast (30mg)

Marketer

Grievers Remedies

Storage

Store below 30°C
The content is shown in English
Otelast 30mg Tablet image
Otelast 30mg Tablet image

Product introduction

Otelast 30mg Tablet can be taken with or without food. Take it regularly and do not stop taking the medicine even if you get better until your doctor tells you it is right to stop. You may need to monitor your weight regularly while taking the medicine, as it may cause weight loss.


Using Otelast 30mg Tablet may cause a few common side effects, such as nausea, diarrhea, vomiting, headache, and upper respiratory tract infection. If these side effects persist or get worse, let your doctor know. Your doctor may help with ways to reduce or prevent these symptoms by prescribing alternative medicine or by adjusting the dose.


To make sure the medicine is safe for you, let your doctor know about all the other medicines you are taking before taking Otelast 30mg Tablet. Inform your doctor if you have any issues with your kidneys, liver, heart, etc. If you are pregnant or breastfeeding, consult your doctor first before taking this medicine.

Uses of Otelast Tablet

  • Plaque psoriasis

Benefits of Otelast Tablet

Plaque psoriasis
Plaque psoriasis is the most common form of psoriasis, a condition where the skin cells in the body grow too quickly and form scales and dry patches. They can grow anywhere, but most appear on the scalp, elbows, knees, and lower back. Otelast 30mg Tablet reduces the scaly, itchy patches which may develop on the different parts of the body. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Otelast Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Otelast
  • Diarrhea
  • Nausea
  • Vomiting
  • Headache
  • Upper respiratory tract infection

How to use Otelast Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Otelast 30mg Tablet may be taken with or without food.

How Otelast Tablet works

Otelast 30mg Tablet is a phosphodiesterase 4 (PDE4) inhibitor. It works by blocking the action of certain chemical messengers that are responsible for inflammation associated with psoriatic arthritis and psoriasis, and thereby reduces the signs and symptoms of these conditions.

All substitutes for Otelast 30mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Aprezo 30mg Tablet

by Glenmark Pharmaceuticals Ltd
₹30.8/tablet
25% cheaper
<h3 class=bodySemiBold>Aprezo 30mg Tablet</h3>

Mprila Tablet

by Mylan Pharmaceuticals Pvt Ltd - A Viatris Company
₹23.6/tablet
43% cheaper
<h3 class=bodySemiBold>Mprila Tablet</h3>

Apraize 30 Tablet

by Ipca Laboratories Ltd
₹30.6/tablet
26% cheaper
<h3 class=bodySemiBold>Apraize 30 Tablet</h3>

APXenta 30mg Tablet

by Ajanta Pharma Limited
₹28.2/tablet
31% cheaper
<h3 class=bodySemiBold>APXenta 30mg Tablet</h3>

Aprenext 30mg Tablet

by Indiabulls pharmaceutical ltd
₹26.7/tablet
35% cheaper
<h3 class=bodySemiBold>Aprenext 30mg Tablet</h3>

Quick tips

  • Otelast 30mg Tablet is a well-tolerated medicine. Mild stomach upset may occur early during the treatment.
  • Monitor your weight regularly, as Otelast 30mg Tablet may cause weight loss.
  • Your doctor will gradually increase the dose from day 1 to day 6 of treatment, after which it may be kept constant.
  • Tell your doctor immediately if you experience new or worsened depression, suicidal thoughts, other mood changes, or unexplained weight loss.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Otelast 30mg Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Otelast 30mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Otelast 30mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Otelast 30mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Otelast 30mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

SAFE IF PRESCRIBED
Otelast 30mg Tablet is safe to use in patients with liver disease. No dose adjustment is recommended.

Frequently asked questions

No, Otelast 30mg Tablet is not an immunosuppressant. It belongs to a class of medicines known as phosphodiesterase 4 inhibitors (PDE4), which work by blocking the activity of PDE4. PDE4 is found in inflammatory cells, and blocking it helps in reducing the molecules responsible for inflammation.
Otelast 30mg Tablet is used to treat plaque psoriasis (red, scaly, thick, itchy, painful patches on skin) and psoriatic arthritis (a condition that causes joint pain and swelling). It is a long-term treatment and may take about 16 weeks to show an improvement.
Yes, Otelast 30mg Tablet may cause depression as a side effect. The patient may also develop suicidal thoughts. It should be avoided in patients with a history of depression. In case you develop any of these symptoms, consult your doctor immediately or ask your friends or relatives to help you seek medical advice.
Yes, Otelast 30mg Tablet may cause a decrease in appetite, which may further cause weight loss. You should monitor your weight regularly while on treatment with Otelast 30mg Tablet. In case of significant weight loss, consult your doctor and consider stopping Otelast 30mg Tablet.
Be sure to take Otelast 30mg Tablet exactly as directed by your doctor. Your doctor will prescribe a low dose initially. This dose will be increased gradually after 6 days. Swallow the tablets whole with water. You can take it with or without food.
You should not take rifampicin if you are taking Otelast 30mg Tablet. Rifampicin interferes with the working of Otelast 30mg Tablet by decreasing its levels, making it less effective. As a result, you may not see any improvement after taking Otelast 30mg Tablet.
In case you get pregnant while taking Otelast 30mg Tablet, you should inform your doctor immediately. In fact, pregnancy should be avoided during treatment with this medicine. The reason being, according to animal studies, with Otelast 30mg Tablet, there may be a risk of baby loss or defects in the unborn baby.

Fact Box

Chemical Class

Phthalimides

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Phosphodiesterase-IV inhibitors (PsA & PSO)

References

  1. Apremilast [Product Information]. Thousand Oaks, CA: Amgen Inc.; 2021. [Accessed 20 Feb. 2024] (online) Available from:
  2. Apremilast [Prescribing Information]. Thousand Oaks, CA: Amgen Inc.; 2024. [Accessed 03 Apr. 2024] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Grievers Remedies
Address: Srinivasa Nagar, Tiruchirappalli, Tamil Nadu

Vendor Details

Country of origin: India

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