Pegstim Injection
Prescription Required
Product introduction
Pegstim Injection is used to prevent infections after chemotherapy. It is a growth factor that stimulates bone marrow to produce white blood cells. These cells protect the body against infections.
Pegstim Injection is given as an injection by a qualified medical professional. You should continue to take as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You might be asked for regular tests done to check the number of blood cells in your blood and your bone density level while you are taking this medicine.
The most common side effects of this medicine include bone pain, joint pain, headache, nausea, and muscle pain. Other than this, pain or redness at the site of injection is common. But, inform your doctor if you notice a lump, swelling, or bruising that does not go away. It might not prevent you from all kinds of infection, hence inform your doctor if you notice fever, chills, shortness of breath, sore throat, and swelling around the face or neck.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You must avoid driving or attention-seeking activity if you experience dizziness after taking this medicine.
Pegstim Injection is given as an injection by a qualified medical professional. You should continue to take as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You might be asked for regular tests done to check the number of blood cells in your blood and your bone density level while you are taking this medicine.
The most common side effects of this medicine include bone pain, joint pain, headache, nausea, and muscle pain. Other than this, pain or redness at the site of injection is common. But, inform your doctor if you notice a lump, swelling, or bruising that does not go away. It might not prevent you from all kinds of infection, hence inform your doctor if you notice fever, chills, shortness of breath, sore throat, and swelling around the face or neck.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You must avoid driving or attention-seeking activity if you experience dizziness after taking this medicine.
Uses of Pegstim Injection
- Prevention of Infections after chemotherapy
Benefits of Pegstim Injection
In Prevention of Infections after chemotherapy
Pegstim Injection increases the production of white blood cells by stimulating the immune system in our body. White blood cells are those cells that help us to fight infections. This medicine is really effective and must be used under medical supervision. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.
Side effects of Pegstim Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pegstim
- Bone pain
- Joint pain
- Headache
- Nausea
- Low blood platelets
- Muscle pain
- Back pain
- Pain in extremities
- Injection site pain
How to use Pegstim Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Pegstim Injection works
Pegstim Injection is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections.
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Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pegstim Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Pegstim Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Pegstim Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Pegstim Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Pegstim Injection is safe to use in patients with kidney disease. No dose adjustment of Pegstim Injection is recommended.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Pegstim Injection in patients with liver disease. Please consult your doctor.
What if you forget to take Pegstim Injection?
If you miss a dose of Pegstim Injection, please consult your doctor.
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Quick tips
- Pegstim Injection reduces the risk of infection in people treated with chemotherapy.
- It is usually given as a daily injection into the tissue just under the skin or into the vein.
- You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant.
- Store it in the refrigerator, protect it from light, and don't shake it.
- For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it.
- Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away.
- Use caution while driving or doing anything that requires concentration as Pegstim Injection may cause dizziness.
- Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine.
- Stop taking Pegstim Injection and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.
Fact Box
Chemical Class
Granulocyte Colony-Stimulating Factor
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Granulocyte-colony stimulating factor (G-CSF)
Interaction with drugs
Taking Pegstim with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Gemcitabine from 14 days before until 24 days after taking Pegfilgrast
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Azathioprine from 14 days before until 24 days after taking Pegfilgras
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Bendamustine from 14 days before until 24 days after taking Pegfilgras
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Vinorelbine from 14 days before until 24 days after taking Pegfilgrast
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Idarubicin from 14 days before until 24 days after taking Pegfilgrasti
Patient concerns
User feedback
Patients taking Pegstim Injection
Once A Month
54%
Once A Day
29%
Once A Week
11%
Twice A Month
6%
What are you using Pegstim Injection for?
Infections af*
100%
*Infections after chemotherapy
How much was the improvement?
Average
50%
Excellent
25%
Poor
25%
What were the side-effects while using Pegstim Injection?
No Side Effec*
40%
Headache
20%
Bone pain
20%
Low blood pla*
20%
*No Side Effect, Low blood platelets
How do you take Pegstim Injection?
With or witho*
67%
Empty stomach
33%
*With or without food
Please rate Pegstim Injection on price
Expensive
67%
Not Expensive
22%
Average
11%
FAQs
What is Pegstim Injection? How is it given?
Pegstim Injection belongs to a class of medications called colony stimulating factors. It helps reduce the chances of infections and side effects related to chemotherapy and does not directly treat cancer. It comes as a solution (liquid) to inject subcutaneously (under the skin), 24 hours after chemotherapy. It may be injected by a doctor/nurse in a hospital or you may be shown how to use injections at home
How does pegfilgrastim work?
Pegfilgrastim belongs to a class of medications called colony stimulating factors. It acts on hematopoietic cells (cells in the bone marrow that produce red blood cells, white blood cells, and platelets) to increase production of neutrophils (a type of white blood cell) in the body.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Masters SB. Agents Used in Anemias; Hematopoetic Growth Factors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 581.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1074-75.
- Pegfilgrastim. Cambridge, UK: Amgen Ltd.; 2002 [revised Sep. 2018]. [Accessed 28 Jan 2019] (online) Available from:
- Medscape. Pegfilgrastim. [Accessed 26 Mar. 2019] (online) Available from:
Marketer details
Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Country of origin: India
Expires on or after: November, 2026
A licensed vendor partner from your nearest location will deliver Pegstim Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: November, 2026
A licensed vendor partner from your nearest location will deliver Pegstim Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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0.6 ml in 1 prefilled syringe
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