Pencom 600000IU Injection

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 14 Apr 2026 | 04:20 PM (IST)

Pencom 600000IU Injection is an antibiotic used to treat a variety of bacterial infections. It is effective in treating sore throat and sexually transmitted diseases like Syphilis. This medicine is also used to prevent some bacterial infections such as Rheumatic fever.

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Penidure LA 6 Injection

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Pencom 600000IU Injection

vial of 5 ml Injection

₹6.4

₹7

Same composition

Penidure LA 6 Injection

vial of 1 ml Injection

Benzathine penicillin G (600000IU)

by Pfizer Ltd

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General Information

Contains

Benzathine penicillin G (600000IU)

Marketer

Alembic Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Pencom 600000IU Injection is a long-acting type of penicillin, which mainly fights and stops the growth of the gram-positive type of bacteria. It is given as an injection into the muscle under the supervision of a healthcare professional. It should be used regularly as per the schedule prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication

Rash, allergic reactions or pain, swelling, and redness at the site of injection may be seen as side effects in some patients. These are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens.

Before taking this medicine, inform your doctor if you are allergic to penicillin or any penicillin-type of medicine. This medicine is generally regarded as safe to use during pregnancy if used under a doctor’s supervision.

Uses of Pencom Injection

Benefits of Pencom Injection

Treatment of Bacterial infections
Pencom 600000IU Injection is an antibiotic medicine which can be used to treat many different infections caused by bacteria. It works by stopping the growth of the bacteria causing the infection. This medicine is given by a doctor or a nurse and should not be self-administered. It usually makes you feel better quite quickly. You must continue the treatment as prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant.

Prevention of Rheumatic fever
Rheumatic fever is an inflammatory disease caused by the bacteria streptococcus, that results usually die to inadequately treated throat infections or scarlet fever caused by the same microorganisms. Pencom 600000IU Injection effectively relieves symptoms, controls inflammation and also prevents the disease from returning. If you are allergic to penicillin, tell your doctor before taking it, so you may be treated with some other alternate medicine. If you are using it for the first time, let your doctor know if you notice any signs of allergy such as rash, swelling or any other bothersome side effect.

Side effects of Pencom Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pencom

Rash
Allergic reaction
Injection site reactions (pain, swelling, redness)

How to use Pencom Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pencom Injection works

Pencom 600000IU Injection is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

All substitutes for Pencom 600000IU Injection

For information purposes only. Consult a doctor before taking any medicine.

Penidure LA 6 Injection

by Pfizer Ltd

₹12.47/injection

78% costlier

Quick tips

You have been prescribed Pencom 600000IU Injection for the treatment of bacterial infections.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.
You have been prescribed Pencom 600000IU Injection for the treatment of bacterial infections.
It is given by an injection into a vein or muscle, or via a drip into a vein.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Pencom 600000IU Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Pencom 600000IU Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Pencom 600000IU Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

CONSULT YOUR DOCTOR

It is not known whether Pencom 600000IU Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Pencom 600000IU Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Pencom 600000IU Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Pencom with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Benzathine penicillin G. Please consult your doctor. Benzathine penicillin G may reduce the efficacy of Cholera Vaccine (Inactivated).

Moderate

Amikacin (Injection Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Kanamycin (Injection Route)

Let your doctor know if you have a history of kidney disease. Your doctor may monitor your kidney function regularly.

Moderate

Streptomycin (Injection Route)

Let your doctor know if you have a history of kidney disease. Your doctor may monitor your kidney function regularly.

Moderate

Methotrexate (Oral Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Benzathine penicillin G may reduce the efficacy of Methotrexate.

Frequently asked questions

Can Pencom 600000IU Injection cause an allergic reaction?

Can Pencom 600000IU Injection cause an allergic reaction?<br>Yes. Pencom 600000IU Injection may cause an allergic reaction, although it is rare. Get emergency medical help if you have any of the signs of an allergic reaction, such as hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

What should I discuss with my doctor before receiving Pencom 600000IU Injection?

Before taking Pencom 600000IU Injection, you should tell your doctor if you have ever had an allergic reaction to Pencom 600000IU Injection or any similar medicine. Inform the doctor if you have any type of allergy, asthma or breathing problems, heart disease or kidney disease. Let your doctor know about all the medicines that you may be taking as they may affect or be affected by Pencom 600000IU Injection. Pregnant or breastfeeding mothers should also seek their doctor’s advice before taking Pencom 600000IU Injection.

Why does Pencom 600000IU Injection shot hurt so much?

Pencom 600000IU Injection is injected deeply into the muscle, usually into the butt muscle, using a lot of fluid used to inject it. Moreover, it is injected slowly which makes it even more painful.

How is Pencom 600000IU Injection given?

Pencom 600000IU Injection must be injected slowly and deeply into a muscle of the buttock or hip. Do not inject this medicine near or into an artery, vein, or nerve as it could lead to some serious side effects.

The solution looks discolored. Can I still use Pencom 600000IU Injection?

No. You should not use Pencom 600000IU Injection if the medicine has changed colors or has particles in it. The discolored solution may be contaminated and may not be as effective as it is expected to be. Also, it may cause additional side effects. So, it is better, that you discard the solution and go for another vial.

I feel better now. Can I stop taking Pencom 600000IU Injection?

No. Make sure to receive all doses your doctor has prescribed, even if you feel better. This is because your symptoms may have improved but chances are that the infection is still present in your body. Skipping doses can increase the risk of developing an infection that is resistant to medication. So, continue taking Pencom 600000IU Injection as prescribed. After you have finished all the doses, your doctor may advise you on some tests to make sure your infection has completely cleared up.

Does Pencom 600000IU Injection treat the flu?

No. Pencom 600000IU Injection does not treat a viral infection such as the flu or a common cold.

Fact Box

Chemical Class

Dipeptides

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Narrow Spectrum Penicillins

Related lab tests

Complete Blood Count

Peripheral Smear Examination

Rapid Plasma Reagin

References

Chambers HF, Deck DH. Beta-Lactam and Other Cell Wall- & Membrane-Active Antibiotics. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 778-79.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1081-82.
PubChem. Benzathine penicillin G. [Accessed 29 Mar. 2019] (online) Available from:
Benzathine penicillin G. Bristol, TN: King Pharmaceuticals; Aug. 2012. [Accessed 29 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Alembic Pharmaceuticals Ltd
Address: Alembic Road, Vadodara - 390 003, Gujarat,INDIA

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Pencom 600000IU Injection

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Pencom Injection

Benefits of Pencom Injection

Side effects of Pencom Injection

How to use Pencom Injection

How Pencom Injection works

All substitutes for Pencom 600000IU Injection

Penidure LA 6 Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cholera Vaccine (Inactivated) (Oral Route)

Amikacin (Injection Route)

Kanamycin (Injection Route)

Streptomycin (Injection Route)

Methotrexate (Oral Route)

Frequently asked questions

Can Pencom 600000IU Injection cause an allergic reaction?

What should I discuss with my doctor before receiving Pencom 600000IU Injection?

Why does Pencom 600000IU Injection shot hurt so much?

How is Pencom 600000IU Injection given?

The solution looks discolored. Can I still use Pencom 600000IU Injection?

I feel better now. Can I stop taking Pencom 600000IU Injection?

Does Pencom 600000IU Injection treat the flu?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

Rapid Plasma Reagin

References

User feedback

How much was the improvement?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests