Phetoin 100mg Tablet is a prescription medicine used to treat and prevent epilepsy (seizures). It controls seizures by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Phetoin 100mg Tablet can be used alone or in combination with other medicines. It should be taken in the dose and duration as advised by your doctor. This may increase gradually until your condition is stable. This medicine may take several weeks to work but it is important to take it regularly to get the benefit. Do not stop taking it, even if you feel fine, unless your doctor advises you to. You may have more seizures, or your bipolar disorder may get worse.

The most common side effects of this medicine include skin involuntary eye movement, lack of coordination, slurred speech, mental confusion, nausea, vomiting, constipation, and rash. Most side effects wear off, but if they bother you or do not go away, tell your doctor. There may be ways of preventing or reducing these effects.

Before taking this medicine, tell your doctor if you have kidney or liver problems, meningitis or depression or suicidal thoughts. Also let your healthcare team know about all other medications you are using as some may affect, or be affected by, this medicine, including contraceptive pills. If you are pregnant or breastfeeding, Phetoin 100mg Tablet can be taken if it is clearly needed but the dose may be adjusted. You should avoid driving or riding a bicycle if this medicine makes you drowsy or dizzy. You may need frequent blood tests to check how you are responding to this medicine.

Uses of Phetoin Tablet

Benefits of Phetoin Tablet

In Treatment and prevention of Epilepsy/Seizures

Phetoin 100mg Tablet is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.
This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

Side effects of Phetoin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Phetoin

Rash
Vomiting
Nausea
Slurred speech
Confusion
Nystagmus (involuntary eye movement)
Coordination disorder

How to use Phetoin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Phetoin 100mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Phetoin Tablet works

Phetoin 100mg Tablet is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Phetoin 100mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Phetoin 100mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Phetoin 100mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Phetoin 100mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Phetoin 100mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Phetoin 100mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Phetoin 100mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Phetoin 100mg Tablet may be needed. Please consult your doctor.

What if you forget to take Phetoin Tablet?

If you miss a dose of Phetoin 100mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Phetoin 100mg Tablet

₹1.32/Tablet

Epsolin 100 Tablet

Zydus Cadila

₹1.93/tablet

46% costlier

Celetoin 100 Tablet

Intas Pharmaceuticals Ltd

₹1.97/tablet

49% costlier

Eptoin Tablet

Abbott

₹1.97/tablet

49% costlier

Epsod 100mg Tablet

Shine Pharmaceuticals Ltd

₹1.83/tablet

39% costlier

Phenos 100mg Tablet

D D Pharmaceuticals

₹1.94/tablet

47% costlier

View all substitutes

Quick tips

Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
Some healthy tips to prevent seizures:
- Practice yoga every day.
- Get enough sleep at nighttime.
- Limit the use of screen time such as mobile/laptop.
- Take your medication on time.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
It may increase blood sugar levels. Inform your doctor if you are taking any medicines to treat diabetes.
It may cause swollen gum (gum hypertrophy), hence take care of oral or dental hygiene.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Fact Box

Chemical Class

Hydantoin Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Sodium Channel Modulators- Antiepileptic drugs (AEDs)

Interaction with drugs

Taking Phetoin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Aripiprazole (Oral Route) Severe

Phenytoin may reduce blood levels of Aripiprazole. If concurrent use is essential, please consult your doctor. They may monitor your treatment and adjust the doses as per the obse... More

Acenocoumarol (Oral Route) Severe

Concurrent use may increase the risk of severe bleeding. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Ranolazine (Oral Route) Severe

Phenytoin may reduce blood levels and efficacy of Ranolazine. Do not consume Ranolazine with Phenytoin.

Ticagrelor (Oral Route) Severe

Phenytoin may reduce blood levels of Ticagrelor. Do not consume Ticagrelor with Phenytoin.

Acetazolamide (Oral Route) Severe

Concurrent use may cause bone problems. If concurrent use is essential, watch out for symptoms such as blurred vision, sedation, drowsiness, impaired coordination, or impairment o... More

View all drug interactions

Patient concerns

She has problem of epilepsy from last two years

Dr. Rahul Yadav

Paediatrics

Hello, epilepsy and seizures cannot be treated online without physically examining the child and detailed history.

Left side headache while laughing or coughing for 20 seconds only Pls suggest

Dr. Pushkar Mani

Physician

could be trigeminal neuralgia/ TM joint stifness or migrainerefer to ENT doctor and Neurophysician

I m taking 1.5gm sodium valporate,1.5 levectram, 1gm clobezam then also seizure r their at period of weekly is there alternate treatment in Ayurveda as every time at multiplying the doses at every visit As MRI eeg every tests r normal

Dr. M. K. Ansari

Neurology

not aware of any ayurvedic medications for epilepsy is not my specialization. However you seems to have difficult to control (intractable) seizures plz follow doctors advice deligently for ur own welfare

?? ???? ?????? ?? ?????? ?? ?? ??? encorate Charon 200 500 tablet use krta hu kya iska koi solution h Jisse main completely thk ho jau

Dr. Jyoti Kapoor Madan

Psychiatry

Epilepsy requires regular treatment with anticonvulsants like encorate chrono for at least 3 years of seizure free period after which medicines may be tapered off unless seizures reappear. At present, there are no other effective treatment options.

FAQs

For how long does Phetoin 100mg Tablet stay in your system?

On an average, Phetoin 100mg Tablet may stay in your system for 5-6 days. This duration varies from person to person. In some cases, it may stay for about 9-10 days.

What happens if I stop taking Phetoin 100mg Tablet?

Suddenly stopping Phetoin 100mg Tablet may cause non-stop seizures (called status epilepticus), which can endanger life. Do not stop taking the medicine without consulting your doctor. If required, your doctor will slowly reduce the dose before stopping it completely.

What are the symptoms that occur if I take more than the recommended dose of Phetoin 100mg Tablet? Can I die from Phetoin 100mg Tablet overdose?

Overdose of Phetoin 100mg Tablet may cause jerky movements of the eyes (nystagmus), unclear speech, loss of balance, tremor, muscle stiffness or weakness, nausea, vomiting, lightheadedness, fainting, blurred vision, slow and shallow breathing and even coma. Phetoin 100mg Tablet overdose can cause very low blood pressure and respiratory problems. As a result of this, the patient can even die.

Who should avoid taking Phetoin 100mg Tablet?

You should not take Phetoin 100mg Tablet if you have liver disease, especially if you have a history of developing a liver problem due to Phetoin 100mg Tablet. Also, patients taking Delavirdine (a medicine used in the treatment of HIV infection) should not take Phetoin 100mg Tablet. Phetoin 100mg Tablet may reduce the effectiveness of Delavirdine on HIV and the virus may also become resistant to Delavirdine. It is advised that you inform your doctor if you have any existing heart disorder before you receive Phetoin 100mg Tablet.

Can I take Phetoin 100mg Tablet with ibuprofen?

Phetoin 100mg Tablet can be taken with ibuprofen. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.

What are the effects of Phetoin 100mg Tablet on children?

The most common side effects related to Phetoin 100mg Tablet in children are jerky movements of the eyes (nystagmus) and overgrowth of the gums. In some children, Phetoin 100mg Tablet causes problems with thinking or behavior, mood change, slow or clumsy movements, or a loss of energy. Other side effects from high doses include unsteadiness in the feet and hands, sleepiness, and vomiting. These may be avoidable if the dose is increased slowly. These side effects quickly disappear when the dose is reduced.

Does Phetoin 100mg Tablet cause weight gain?

Phetoin 100mg Tablet has not been reported to cause weight gain. However, weight loss can occur with longer term use of a higher dose of Phetoin 100mg Tablet. Please consult your doctor if you experience weight gain after taking Phetoin 100mg Tablet.

Does Phetoin 100mg Tablet make you sleepy?

Phetoin 100mg Tablet can make you feel sleepy (sedation, somnolence, and drowsiness). Please consult your doctor if you feel very sleepy after taking Phetoin 100mg Tablet, especially during the first few weeks of treatment or following a dose increase. Talk to your doctor as you may be advised not to drive or use machines until it is established that your ability to perform such activities is not affected.

Does Phetoin 100mg Tablet affect birth control?

Phetoin 100mg Tablet does affect birth control. Phetoin 100mg Tablet can decrease the effect of oral contraceptives (birth control pills) which can make the contraceptive (birth control) effect unreliable. Please talk to your doctor if you are asked to take the two medicines together as you may need to use extra protection for birth control.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 591-93.
Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 403-405.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1111-116.
Phenytoin. Cedex, France: Famar Orleans; 2018. [Accessed 22 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 22 Mar. 2019] (online) Available from:
Phenytoin. New York, New York: Pfizer; 2009]. [Accessed 22 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Phenytoin sodium [FDA Label]. Mumbai, India: Wockhardt Limited; 2007. [Accessed 28 Mar. 2023] (online) Available from:
Phenytoin [Prescribing Information]. New York, NY: Parke Davis; 2009. [Accessed 31 May 2024] (online) Available from:

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