Product introduction
Pivikto 150mg Tablet is used to treat certain types of breast cancer, like hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, PIK3CAmutated, advanced or breast cancer which has spread to other organs. It is given together with hormonal anticancer therapies.
Pivikto 150mg Tablet should be taken with food, but try to take it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. Take it exactly as advised by the doctor. Taking it the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some common side effects of this medicine include fatigue, decreased appetite, rash, vomiting, and diarrhea. It may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby increasing the susceptibility to infections. It is better to inform your doctor if you notice symptoms of infection like fever, chills, weakness, bleeding or bruising, and nose bleeding. It might also cause dizziness; so avoid driving or attention-seeking activities if you experience dizziness.
Before taking Pivikto 150mg Tablet, tell your doctor if you have heart disease, liver or kidney problems, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine, so let your healthcare team know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during the treatment with this drug is important to avoid pregnancy.
There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.
Benefits of Pivikto Tablet
Side effects of Pivikto Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pivikto
- Diarrhea
- Rash
- Increased glucose level in blood
- Nausea
- Vomiting
- Fatigue
- Increased creatinine level in blood
- Lymphocytopenia
- Increased gamma-glutamyltransferase
- Increased alanine aminotransferase
- Decreased hemoglobin
- Increased lipase in the blood
- Decreased appetite
- Stomatitis (Inflammation of the mouth)
- Weight loss
- Hypoglycemia (low blood glucose level)
- Decreased calcium level in blood
- Prolonged activated partial thromboplastin time (aPTT)
- Hair loss
How to use Pivikto Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pivikto 150mg Tablet is to be taken with food.
How Pivikto Tablet works
Pivikto 150mg Tablet works to treat cancer by blocking the signals that cause cancer cells to multiply, which helps to stop the spread of cancer cells.
Safety advice
AlcoholCONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pivikto 150mg Tablet. Please consult your doctor.
PregnancyCONSULT YOUR DOCTOR
Pivikto 150mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feedingCONSULT YOUR DOCTOR
Pivikto 150mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
DrivingCONSULT YOUR DOCTOR
It is not known whether Pivikto 150mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
KidneyCONSULT YOUR DOCTOR
There is limited information available on the use of Pivikto 150mg Tablet in patients with kidney disease. Please consult your doctor.
Pivikto 150mg Tablet is safe to use in patients with liver disease. No dose adjustment of Pivikto 150mg Tablet is recommended.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- After starting your treatment with Pivikto 150mg Tablet, you may be at risk of infection, so try to avoid crowds or people with colds. Report fever or any other signs of infection immediately to your doctor.
- Drink at least two to three-quarter fluid every 24 hours, unless you are instructed otherwise.
- To reduce nausea, take antinausea medications as prescribed by your doctor, and eat small, frequent meals.
- Inform your doctor if you notice any signs or symptoms of allergic reactions, like rash or shortness of breath, after taking Pivikto 150mg Tablet.
- Monitor your sugar levels at intervals and report to your doctor if they are abnormally high. The doctor will be able to advise more on this.
- Eat foods that may help reduce diarrhea and take adequate rest.
- Use a soft toothbrush and rinse your mouth at least 3 times a day with saline water to help treat/prevent mouth sores.
- After starting your treatment with Pivikto 150mg Tablet, you may be at risk of infection, so try to avoid crowds or people with colds. Report fever or any other signs of infection immediately to your doctor.
- Drink at least two to three-quarter fluid every 24 hours, unless you are instructed otherwise.
- To reduce nausea, take antinausea medications as prescribed by your doctor, and eat small, frequent meals.
- Inform your doctor if you notice any signs or symptoms of allergic reactions, like rash or shortness of breath, after taking Pivikto 150mg Tablet.
- Monitor your sugar levels at intervals and report to your doctor if they are abnormally high. The doctor will be able to advise more on this.
- Eat foods that may help reduce diarrhea and take adequate rest.
- Use a soft toothbrush and rinse your mouth at least 3 times a day with saline water to help treat/prevent mouth sores.
Fact Box
Chemical Class
Proline and derivatives
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Anticancer-others
Interaction with drugs
Taking Pivikto with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may interfere with control over blood sugar.
Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.
Concurrent use may interfere with control over blood sugar.
Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.
Concurrent use may interfere with control over blood sugar.
Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.
Concurrent use may interfere with control over blood sugar.
Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.
Leflunomide may raise blood levels of Alpelisib.
Do not consume Alpelisib with Leflunomide. If concurrent use is essential, your doctor may monitor your treatment and adjust the d... More
Patient concerns
If any symtom of brest cancer if have whats the cure
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
First is confirmation of breast cancerChance of cure depends on stage of cancer
BREAST CANCER , PET REPORT SAYS INFECTION IN SKELETON.
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Metastatic breast cancer, send me previous treatment details
I am PATIENT have pain in my breastes and feel very weight before one week of my menstrual perieds date Is it any symptoms of breast cancer ? Need your advice And also having back pain during menstrual dates please give your valubel advice
Dr. Suman Rao
Obstetrics and Gynaecology
No it's not a symptom of breast cancer.
How to diagonise breast cancer?
Dr. Vijay Sharnangat
Medical Oncology and Hematology
It should be diagnosed by mammogram and biopsy
left breast cancer had amplated
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Please write complete information
She has breast cancer at 4 sta
Dr. Rohan Khandelwal
Surgical Oncology
Dear PATIENT 4 Breast Cancer means that the cancer has spread to other parts of the body. The management of such cancers depends on the site where the cancer has spread and on the receptor status of the breast cancer. If you can share the details with me, I will be happy to let you know the potential management
Can a hard mass in the breast be a breast cancer?
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
It can be benign also, u can get examined by doctorHowever at age of 20 to 25 less likely to be cancer
I am herewith forwarding you biopsy report, please suggest further course of treatment.
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
U have a high risk of breast cancerSend me ur Mammography reports also
Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
Alpelisib [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2022. [Accessed 22 Feb. 2023]. (online) Available from:
Marketer details
Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Country of origin: Switzerland