PlasmaRab Injection is used with rabies vaccine to prevent Rabies. It works by giving your body the antibodies it needs to protect against the rabies virus. It is administered only once, at the beginning of anti-rabies prophylaxis, to previously unvaccinated persons.
PlasmaRab Injection is given as an injection by a doctor or nurse. It must always be used in combination with a rabies vaccine. Post-exposure prophylaxis consists of a regimen of one dose of immunoglobulin and full courses of rabies vaccination. This should be given as soon as possible after exposure. Both active (vaccine) and passive immunization (Immunoglobulin) prevent the rabies virus from infiltrating the central nervous system, but become ineffective once the virus has crossed into the central nervous system. PlasmaRab Injection is administered only once in a lifetime.
The most common side effects include pain, anaphylactic reaction, angioedema (swelling of deeper layers of skin), injection site stiffness, soreness, and tenderness. They do not normally last very long. Sitting or lying down can sometimes help. Consult your doctor if any of the side effects persist or worry you.
Before having the injection, you should tell your doctor if you’ve ever had an allergic reaction to an immunoglobulin. Some other medicines may react with the human rabies immunoglobulin so talk to your doctor about other medications you are taking as well. You should consult your doctor first if you are pregnant or breastfeeding.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of PlasmaRab
Headache
Muscle pain
Joint pain
Dizziness
Fatigue
Fever
Soreness
Pain in extremity
Vomiting
How to use PlasmaRab Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How PlasmaRab Injection works
PlasmaRab Injection works by giving your body the antibodies it needs to protect it against the rabies virus. This is called passive protection.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with PlasmaRab Injection. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
PlasmaRab Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
CAUTION
PlasmaRab Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving
SAFE
PlasmaRab Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
PlasmaRab Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of PlasmaRab Injection may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
PlasmaRab Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of PlasmaRab Injection may not be needed in these patients. Please consult your doctor.
What if you forget to take PlasmaRab Injection?
If you miss a dose of PlasmaRab Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
PlasmaRab Injection protects you against rabies after you have been bitten, scratched, or injured by a suspected animal with rabies.
It is given with the first dose of rabies vaccine, or not more than 7 days after the scratch or injury.
It is given by injection around the wound and into the muscle at the side of the thigh (intramuscular).
Protects you against rabies after you have been bitten, scratched or received any injury from a suspected animal with rabies.
Given with first dose of rabies vaccine, or not more than 7 days after the scratch or injury.
Given by injection around the wound and into the muscle at the side of the thigh (intramuscular).
Fact Box
Chemical Class
Vaccines
Habit Forming
No
Therapeutic Class
VACCINES
Action Class
Immunoglobulin
Patient concerns
Prevention of acene and pimples
Dr. Manju Singh
Homeopathy
Wash acne-prone areas only twice a day. Washing removes excess oil and dead skin cells. But too much washing can irritate the skin. Wash affected areas with a gentle cleanser and use oil-free, water-based skin care products. Use non- oily makeup. Choose oil-free cosmetics that won't clog pores. Remove makeup before going to bed. Going to sleep with cosmetics on your skin can clog your pores. Avoid touching or picking at the problem areas. Doing so can trigger more acne. Always use a clean towel or cloth to wipe your face. Always keep your hands clean and wash them regularly so that you may not touch your skin with dirty hands.
I have been bitten by a dog yesterday I have taken rabipur but that was not cpreserved coldly Not taken rabies immunoglobin and going to be 24 hrs what should I do?
PlasmaRab Injection is a solution containing a large amount of rabies antibodies. It is used to provide protection against rabies. It is given either along with the first dose of anti-rabies vaccine(ARV) or not more than 7 days later.
How effective is PlasmaRab Injection?
Rabies is a 100% preventable disease. Proper wound management and simultaneous administration of PlasmaRab Injection combined with anti-rabies vaccine (ARV) is almost invariably effective in preventing rabies, even after high-risk exposure.
Is PlasmaRab Injection necessary?
PlasmaRab Injection is not required for patients who have previously received a complete vaccination series of rabies.
Is PlasmaRab Injection painful?
Whether PlasmaRab Injection is painful or not depends on your pain tolerance. During your initial treatment, a healthcare professional will put PlasmaRab Injection in the area where you were bitten. This can be painful. Therefore, a relatively greater amount of PlasmaRab Injection may be required to be placed in and around the wound site to ease out your pain and treat infection.
Is Equine Rabies Immunoglobulin better than PlasmaRab Injection?
Equine Rabies Immunoglobulin is more economical as compared to PlasmaRab Injection i.e., human rabies immunoglobulin (HRIG). Hence, it is more affordable to patients in developing countries, like India. However, Equine Rabies Immunoglobulin has a high potential to cause anaphylaxis (a severe, potentially life-threatening allergic reaction), serum sickness and other allergic reactions and thus physicians are hesitant to use it.
What is PlasmaRab Injection? What is it used for?
PlasmaRab Injection is a solution containing a large amount of rabies antibodies. It is used to provide protection against rabies. It is given either along with the first dose of anti-rabies vaccine(ARV) or not more than 7 days later.
How effective is PlasmaRab Injection?
Rabies is a 100% preventable disease. Proper wound management and simultaneous administration of PlasmaRab Injection combined with anti-rabies vaccine (ARV) is almost invariably effective in preventing rabies, even after high-risk exposure.
Is PlasmaRab Injection necessary?
PlasmaRab Injection is not required for patients who have previously received a complete vaccination series of rabies.
Is PlasmaRab Injection painful?
Whether PlasmaRab Injection is painful or not depends on your pain tolerance. During your initial treatment, a healthcare professional will put PlasmaRab Injection in the area where you were bitten. This can be painful. Therefore, a relatively greater amount of PlasmaRab Injection may be required to be placed in and around the wound site to ease out your pain and treat infection.
Is Equine Rabies Immunoglobulin better than PlasmaRab Injection?
Equine Rabies Immunoglobulin is more economical as compared to PlasmaRab Injection i.e., human rabies immunoglobulin (HRIG). Hence, it is more affordable to patients in developing countries, like India. However, Equine Rabies Immunoglobulin has a high potential to cause anaphylaxis (a severe, potentially life-threatening allergic reaction), serum sickness and other allergic reactions and thus physicians are hesitant to use it.
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References
Human Rabies Immunoglobulin. Elstree, Hertfordshire; Bio Products Laboratory Limited; 1992 [revised Oct. 2014]. [Accessed 04 Apr. 2019] (online) Available from:
Human Rabies Immunoglobulin. Marburg, Germany: Novartis Vaccines and Diagnostics GmbH; 2005 [revised 24 Nov. 2010]. [Accessed 04 Apr. 2019] (online) Available from:
Rabies Immunoglobulin [Product Information]. Warriewood, Australia: Link Medical Products Pty Ltd.; 2021. [Accessed 19 Oct. 2023] (online) Available from: