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Prabcox 250mg Tablet

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 01 Feb 2026 | 10:29 PM (IST)
Prabcox 250mg Tablet is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment and prevention of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body.
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General Information

Contains

Prothionamide (250mg)

Marketer

Brilliant Lifesciences Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Prabcox 250mg Tablet image
Prabcox 250mg Tablet image

Product introduction

Prabcox 250mg Tablet is given in combination with at least one other tuberculosis medicine. It is used in cases where bacteria have developed resistance to other antibacterial medicines. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at the same time every day. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and in the development of drug-resistant tuberculosis. This can lead to serious health complications.

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects.

Some people may experience loss of appetite, nausea, vomiting, gastric irritation (inflammation of the stomach lining) and sudden lowering of blood pressure on standing (orthostatic hypotension), as side effects of this medicine. Please consult your doctor if these side effects worry you or do not get better.

Inform your doctor if you have diabetes as it can lower the sugar levels in the blood. If you are diabetic, you should monitor your blood sugar regularly. Your doctor may monitor your liver function, vision, and thyroid function while on treatment with this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Prabcox Tablet

Benefits of Prabcox Tablet

Tuberculosis (TB)
Prabcox 250mg Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Prabcox Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Prabcox
  • Loss of appetite
  • Nausea
  • Vomiting
  • Gastric irritation
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Depression
  • Weakness
  • Sleepiness

How to use Prabcox Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prabcox 250mg Tablet may be taken with or without food.

How Prabcox Tablet works

Prabcox 250mg Tablet is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.

Quick tips

  • Prabcox 250mg Tablet is effective at treating tuberculosis when taken together with other antibacterial drugs.
  • It has to be taken for several months in order for it work properly (usually 6 months).
  • Take it with food to avoid stomach upset.
  • It can lower your blood sugar. If you have diabetes, monitor your blood sugar regularly.
  • Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
  • Avoid consuming alcohol while taking this medication.
  • Do not stop taking Prabcox 250mg Tablet even if you start to feel better. Stopping early can result in treatment failure and in the development of drug-resistant tuberculosis. This can be life-threatening and lead to other serious health risks.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Prabcox 250mg Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Prabcox 250mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Prabcox 250mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Prabcox 250mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Prabcox 250mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Prabcox 250mg Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Prabcox 250mg Tablet is an antibiotic medicine used to treat tuberculosis (TB). It is specifically used as a "second-line" treatment for more complicated cases of TB, such as multi-drug resistant tuberculosis (MDR-TB), where the bacteria are no longer responding to the standard, first-choice medicines.<br>
Treating tuberculosis, especially drug-resistant TB, requires taking a combination of several different antibiotics, including Prabcox 250mg Tablet, at the same time. This combination therapy approach is crucial to effectively kill the TB bacteria and prevent them from developing resistance to the medicines.<br>
Treatment for drug-resistant tuberculosis is a very long commitment. You will need to take Prabcox 250mg Tablet, along with your other prescribed TB medicines, for many months, and sometimes for a year, or even longer, as directed by your doctor.<br>
It is absolutely critical to take Prabcox 250mg Tablet exactly as your doctor has prescribed, without skipping any doses. If you stop the treatment early or miss doses, the TB bacteria can start to multiply again, which could make your illness worse and cause the bacteria to become even more resistant to treatment.<br>
Yes. It is generally recommended to take Prabcox 250mg Tablet with food, or right after a meal. Taking the medicine orally with food can help minimize stomach-related side effects such as nausea or upset stomach.<br>
Your doctor will likely prescribe a vitamin B6 supplement, also called pyridoxine, to take along with Prabcox 250mg Tablet. This is standard practice to help prevent a specific neurological side effect known as peripheral neuropathy, which can cause numbness, tingling, or pain in your hands and feet.<br>
Prabcox 250mg Tablet begins to work against the TB bacteria soon after you start taking it. However, because the overall treatment for TB is a slow and gradual process, it may take several weeks before you notice a significant improvement in your symptoms. Patience and adherence to the full treatment plan are key.<br>

Fact Box

Chemical Class

Pyridine derivative

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Mycobacterial cell wall inhibitors-Ethambutol

Related lab tests

Complete Blood Count

Erythrocyte Sedimentation Rate

Mycobacterium Tuberculosis DNA PCR - Qualitative

Peripheral Smear Examination

References

  1. ScienceDirect. Prothionamide. [Accessed 31 Mar. 2019] (online) Available from:
  2. Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Brilliant Lifesciences Pvt Ltd
Address: Brilliant LifeSciences Pvt. Ltd. 401-405, 4th Floor, Lakshmivilla Commercial Complex, Haridarshan Cross Roads, Kathawada Road, Naroda, Ahmedabad, Gujarat, India

Vendor Details

Country of origin: India

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