Prulo 2mg Tablet is a prescription medicine used in the treatment of constipation. It increases the release of certain chemical that improves the movement of food inside the intestine and helps to increase gastric emptying of both liquid and solid.

Prulo 2mg Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you're given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are headache, nausea, abdominal pain, decreased appetite, dizziness, and dyspepsia. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause diarrhea, so it is better to take plenty of fluids while taking this medicine as it may help to prevent dehydration.

Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. You should avoid this medicine if you are suffering from bleeding ulcers of the stomach. Consult with your doctor if are pregnant or breastfeeding.

Uses of Prulo Tablet

Side effects of Prulo Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Prulo

Headache
Nausea
Diarrhea
Abdominal pain
Decreased appetite
Dizziness
Indigestion

How to use Prulo Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prulo 2mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Prulo Tablet works

Prulo 2mg Tablet is a selective 5-HT4 receptor agonist that has high intrinsic activity. It indirectly stimulates the release of acetylcholine, a chemical messenger that increases the motility of the intestine and treats even chronic (long-term) constipation very effectively.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Prulo 2mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Prulo 2mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Prulo 2mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Prulo 2mg Tablet may cause side effects which could affect your ability to drive.
Prulo 2mg Tablet may cause dizziness and tiredness, especially on the first day of treatment, and this may have an effect on driving and use of machines.

Kidney

CAUTION

Prulo 2mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Prulo 2mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Prulo 2mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Prulo 2mg Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Prulo 2mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

What if you forget to take Prulo Tablet?

If you miss a dose of Prulo 2mg Tablet, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Prulo 2mg Tablet

₹30.6/Tablet

Pruvict 2 Tablet

Torrent Pharmaceuticals Ltd

₹36.7/tablet

20% costlier

Prusent 2mg Tablet

Lupin Ltd

₹38.2/tablet

25% costlier

Prugonist 2 Tablet

Mylan Pharmaceuticals Pvt Ltd - A Viatris Company

₹23/tablet

25% cheaper

Presmovac 2 Tablet

Torrent Pharmaceuticals Ltd

₹39.9/tablet

30% costlier

Consticalo 2 Tablet

Torrent Pharmaceuticals Ltd

₹39.9/tablet

30% costlier

View all substitutes

Quick tips

Prulo 2mg Tablet helps treat chronic constipation and improve bowel movements, when laxatives have failed to provide adequate relief.
It can be taken with or without food, at any time of the day.
It may cause diarrhea. Drink plenty of water and inform your doctor if it bothers you.
Inform your doctor if your constipation has not improved even after four weeks of taking this medication.

Fact Box

Chemical Class

Dihydrobenzofurancarboxamide Derivative {benzamides}

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Serotonin 5-HT4 Receptor Antagonists- Prokinetic Agents

Patient concerns

Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers

Dr. Sunil Sekhri

Diabetology

You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed

Restless leg syndrome with irritable bowel syndrome

Dr. Pushkar Mani

Physician

take cobadex czs once daily for 1 monthevion 400 mg once daily for 1 month

FAQs

How quickly does Prulo 2mg Tablet work?

Prulo 2mg Tablet has been found to act rapidly but the effect varies from person to person. This is because the response to a particular medication varies in every patient. Usually, the medicine generates a bowel movement within 2-3 hours. However, it may take about 4-5 days to show complete effect and rapid bowel movements.

Is Prulo 2mg Tablet safe in pregnancy?

No, Prulo 2mg Tablet is not safe to be taken during pregnancy. There are few reported cases of spontaneous abortion that have been noted when given in pregnant women. There is little evidence of use of Prulo 2mg Tablet in pregnant women. Therefore, its use during pregnancy should be avoided. It is important to consult your doctor before starting this medication.

When should I take Prulo 2mg Tablet?

Prulo 2mg Tablet can be taken at any time of the day. Normally, it is taken orally with or without food once daily. The exact dosage of this medication is to be decided by your prescribing physician. Usually, it is taken as 2 milligrams per day.

Can Prulo 2mg Tablet cause gastroparesis?

Prulo 2mg Tablet has been proven to be beneficial in cases of gastroparesis and constipation. Gastroparesis is a condition where there is reduced movement of the gut that leads to delayed emptying of the stomach and constipation. Generally, this occurs in conditions like diabetes or after surgery.

When should I avoid taking Prulo 2mg Tablet?

You should avoid taking Prulo 2mg Tablet if you are allergic to it. It should also be avoided if you have a tear in your stomach or intestinal wall, a bowel blockage or inflammatory conditions of the intestinal wall like Crohn’s disease or ulcerative colitis. Always consult your doctor before starting the medication. The doctor should be informed about any ongoing medication and conditions you have.

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References

Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1327.
Prucalopride succinate. London, England: Shire Pharmaceuticals Limited; 2009 [revised 27 May 2015]. [Accessed 28 Jan. 2019] (online) Available from:
Prucalopride. Baggot Street Lower Dublin: Shire Pharmaceuticals; 2009 [revised Mar. 2019]. [Accessed 28 Mar. 2019] (online) Available from:
Prucalopride [Package Insert]. Gangtok, Sikkim: Torrent Pharmaceuticals Ltd.; 2020. [Accessed 05 Aug. 2023] (online) Available from:

Marketer details

Name: ANT Pharmaceuticals Pvt Ltd

Address: FI-204, Bhumika Residency PI-21, Sector - 20, Kalamboli, Navi Mumbai-410218

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.