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Pruside 50mg Injection

Nitroprusside (50mg)

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Pruside 50mg Injection is a medicine used in the immediate treatment of hypertensive emergency (severely increased blood pressure) and acute heart failure. It brings about an immediate reduction in blood pressure and the workload of the heart.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 09 Sep 2026 | 01:03 AM (IST)

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General Information

Contains

Nitroprusside (50mg)

Marketer

Troikaa Pharmaceuticals Ltd.

Storage

Store below 30°C

The content is shown in English

Product introduction

Pruside 50mg Injection is given as a drip into the vein under the supervision of a doctor. Your doctor is the right person to decide the dose and duration, hence do not try to self-administered the injection at home. Regular monitoring of blood pressure is required while on treatment.

Decreased blood pressure (hypotension) may occur as a side effect of this medicine. Inform your doctor if you are pregnant, planning to conceive or breastfeeding. It is also advisable to avoid medication like sildenafil or tadalafil while on treatment as it may cause a sudden lowering of blood pressure.

Uses of Pruside Injection

Benefits of Pruside Injection

Hypertensive emergency
Hypertensive emergency is a severe and sudden rise in blood pressure that can damage vital organs if not treated immediately. Pruside 50mg Injection rapidly lowers dangerously high blood pressure, helping to protect the brain, heart, and kidneys from serious harm. Its fast-acting relief can be life-saving and helps stabilize the condition for further treatment.

Heart Failure
Heart failure occurs when the heart is unable to pump blood efficiently, leading to symptoms like breathlessness, fatigue, and fluid buildup. Pruside 50mg Injection helps reduce the pressure on the heart by relaxing blood vessels, allowing it to pump more effectively. It eases symptoms quickly and improves heart function, enhancing overall comfort and physical ability.

Side effects of Pruside Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pruside

Cyanide poisoning
Decreased blood pressure

How to use Pruside Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pruside Injection works

Pruside 50mg Injection is a vasodilator. It works by relaxing the muscles in your blood vessels to help them widen and results in the lowering of blood pressure.

All substitutes for Pruside 50mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Nitoside 50mg Injection

by Neon Laboratories Ltd

₹122.16/injection

8% cheaper

Quick tips

Pruside 50mg Injection is given as a drip (intravenous infusion) by your doctor or nurse.
If there is no considerable improvement in blood pressure within 10 minutes, stop the infusion immediately.
It may cause sudden lowering of blood pressure. Hence, regular monitoring of blood pressure is required during treatment.
It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Pruside 50mg Injection as it may cause low blood pressure.
You have been prescribed Pruside 50mg Injection for the prevention and treatment of heart-related chest pain (angina).
Eat healthy (low-fat, high-fiber, low-sodium diet), quit smoking, increase your physical activity, watch your weight and reduce stress.
Pruside 50mg Injection may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Do not consume alcohol while taking Pruside 50mg Injection as it may cause increased dizziness.
It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
You may develop tolerance to Pruside 50mg Injection with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Pruside 50mg Injection as it may cause low blood pressure.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Pruside 50mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Pruside 50mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Pruside 50mg Injection during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Pruside 50mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Pruside 50mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, talk to your doctor if you have any underlying kidney disease.

Liver

UNSAFE

Pruside 50mg Injection is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Pruside with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Vardenafil (Oral Route)

Do not consume Nitroprusside with Vardenafil.

Life-threatening

Avanafil (Oral Route)

Do not consume Nitroprusside with Avanafil.

Life-threatening

Sildenafil (Oral Route)

Do not consume Nitroprusside with Sildenafil.

Life-threatening

Sildenafil (Oral Route)

Do not consume Nitroprusside with Sildenafil.

Life-threatening

Sildenafil (Injection Route)

Do not consume Nitroprusside with Sildenafil.

Frequently asked questions

What is Pruside 50mg Injection used for?

Pruside 50mg Injection belongs to a class of medicines known as vasodilators. It is used to decrease the blood pressure in emergency conditions where the blood pressure is extremely high (hypertensive crisis). It is also used to maintain low blood pressure during surgical procedures in a hospital setting.

Why is Pruside 50mg Injection wrapped in aluminum foil?

Pruside 50mg Injection is wrapped in aluminum foil to protect it from light. This is because Pruside 50mg Injection is very sensitive to light. The solution will degrade every 4 hours if left unprotected. On the contrary, covering it with aluminum foil makes it stable for around 24 hours.

How does Pruside 50mg Injection decrease blood pressure?

Pruside 50mg Injection widens the blood vessels (arteries and veins) which provides a better and smooth path for the blood to flow. This reduces the pressure on the walls which results in effective and significant decrease in the blood pressure.

What are the side effects of Pruside 50mg Injection?

Pruside 50mg Injection may cause side effects like low blood pressure and cyanide poisoning. Additionally, you may also notice abdominal pain, sweating, dizziness, headache, muscle twitching and nausea. However, these are usually not bothersome but if any of these side effects worry you or persist for a longer duration of time, please consult your doctor. Your doctor will suggest ways to manage or prevent these side effects.

Why is Pruside 50mg Injection protected from light?

Pruside 50mg Injection is extremely sensitive to light. If left open, its chemical composition changes rapidly and the color may change from brown to blue or green. If left unprotected, 20% of the solution will deteriorate every 4 hours even in glass bottles. Therefore, it is necessary to prevent exposure of Pruside 50mg Injection to any kind of light, especially fluorescent light.

Fact Box

Chemical Class

Organic transition metal salts

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Nitric Oxide (NO) Donors

References

Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 747-55.
Teerlink JR, Sliwa K, Opie LH. Heart Failure. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 184-86.
Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 179-80.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 989.
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Nitroprusside. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Troikaa Pharmaceuticals Ltd.
Address: Commerce House - 1', Satya Marg, Bodakdev, Ahmedabad-380 054. Gujarat, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Pruside 50mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Home

Cardiac

Antihypertensives Non Herbal Peripherally Acting

Pruside 50mg Injection

Pruside 50mg Injection

Payment, Returns & Expiry

Cash on delivery available

We don’t take this product back

Product expires after Dec, 2026

Price Info

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Pruside Injection

Benefits of Pruside Injection

Side effects of Pruside Injection

How to use Pruside Injection

How Pruside Injection works

All substitutes for Pruside 50mg Injection

Nitoside 50mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Vardenafil (Oral Route)

Avanafil (Oral Route)

Sildenafil (Oral Route)

Sildenafil (Oral Route)

Sildenafil (Injection Route)

Frequently asked questions

What is Pruside 50mg Injection used for?

Why is Pruside 50mg Injection wrapped in aluminum foil?

How does Pruside 50mg Injection decrease blood pressure?

What are the side effects of Pruside 50mg Injection?

Why is Pruside 50mg Injection protected from light?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests