Quel 400mg Tablet SR is used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave) and mania. It is also used to treat bipolar disorders.
Quel 400mg Tablet SR may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms. However, discontinue this medicine immediately if you experience Neuroleptic malignant syndrome (NMS), characterized by fever, muscle rigidity, and altered consciousness or seizures.
Some common side effects of this medicine include decreased hemoglobin levels in the blood, increased triglycerides level in blood, decreased cholesterol level in blood, headache, extrapyramidal symptoms, dry mouth, and withdrawal symptoms. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may increase your weight but, modifying your lifestyle by having a healthy diet and exercising regularly can reduce this side effect.
You should be cautious while using this medicine as it may increase the risk of developing diabetes, so it is better to monitor glucose regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine.
Mania means extremely excited or elevated mood. Quel 400mg Tablet SR helps calm the mood and relax the nerves. This stabilises the mood and prevents the symptoms of mania from recurring again. Taking Quel 400mg Tablet SR will ensure that you have a better social life and are able to do daily activities more comfortably.
In Treatment of Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Quel 400mg Tablet SR helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.
Side effects of Quel Tablet SR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Quel
Weight gain
Constipation
Dizziness
Dryness in mouth
Fatigue
High blood pressure
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Sleepiness
Dyslipidemia
Increased appetite
How to use Quel Tablet SR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Quel 400mg Tablet SR may be taken with or without food, but it is better to take it at a fixed time.
How Quel Tablet SR works
Quel 400mg Tablet SR is an atypical antipsychotic. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Quel 400mg Tablet SR.
Pregnancy
CONSULT YOUR DOCTOR
Quel 400mg Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Quel 400mg Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Quel 400mg Tablet SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Quel 400mg Tablet SR is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Quel 400mg Tablet SR may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Quel 400mg Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Quel 400mg Tablet SR may be needed. Please consult your doctor.
What if you forget to take Quel Tablet SR?
If you miss a dose of Quel 400mg Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
You have been prescribed Quel 400mg Tablet SR for the treatment of schizophrenia and mania.
It is less likely to cause heart problems and movement disorders than other antipsychotics.
It may take 4 to 6 weeks to see treatment effects. Keep taking it as prescribed.
Use caution while driving or doing anything that requires concentration as Quel 400mg Tablet SR can cause dizziness and sleepiness.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
It may increase your weight, blood sugar and cholesterol. Eat healthy, exercise regularly and monitor your blood levels regularly.
Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Do not stop taking it without talking to your doctor first as it may cause worsening of symptoms.
Fact Box
Chemical Class
Dibenzothiazepine Derivatives
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Atypical Antipsychotics
Patient concerns
I am using s vocita and quel sr 50 and migoset for depression and migraine for last 4 months. How can i quit these medicines Can these medicines be discontinued at one go
Dr. Ambrish Dharmadhikari
Psychiatry
We understand your concernWe are here to helpIt is not advisable to stop medications at one goConsult your doctor to gradually reduce dose and stop it eventually
My sister is on medication for schizophrenia since 2005 under Dr. K.K.Sinha of Ranchi. The medicines were stopped in April 2013 However problem reoccurred 4 months later. She was given Quel 200, Joykem 200 and Kamiyan 100. Quel was dropped 6 months later. Power of Joykem and Kamiyan were reduced slowly. For the last 1 year she is taking Prati CR 12.5 as the problem was diminished. But the problem has surfaced again with full severity. Doctor has given date after 2 months. What should be done for the period ? Name of the medicines has been wrongly typed. It's Lamosyn , not Kamiyan. And it's pexti , nor Prati.
Dr. Jyoti Kapoor Madan
Psychiatry
If the patient isn't improving, see your doctor again.
I am taking a medicine for depression for last 3-4 years as i am not able to sleep without this. 1. Dveniz-100mg 2. Quel SR-50mg 3. Stilnocit 12.5mg for BP aten-50mg I am unable to take sound sleep nowdays some time i got up at 2-3 am at midnight. Frequently I use to go for Morning Walk.
Dr. Jyoti Kapoor Madan
Psychiatry
Sleep problems are often caused by underlying physical and/ or psychological cause. This requires examination of the patient so that proper treatment can be initiated. Often stress/ anxiety/ depression or mood disorder needs to be dealt with and sleeping pills are not adequate treatment. In your case, you are probably not on adequate dose of antidepressants and continuous use of zolpidem causes sleep issues in long run. Please go through the link below - http://drjyotikapoor.com/2015/01/26/sleep-disorders/
Suffering from Depression and Mania, what should be done
Dr. Jyoti Kapoor Madan
Psychiatry
Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance.
Mania is a component of Bipolar Affective Disorder. Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance.
I'm suffering from Epilepsy (mainly GTCs) from last 12 years. Currently on Multiple AEDs 1. Topamac 400mg/day, 2. Encorate Chrono 800mg/day, 3. Lonazep 2mg/day. My present problem is I have some onset of agitation and anger and loss my control on my self. Previously I was suggested Quel (quetiapine) 25mg (OD.HS) for anger, but it did not work, recently my Neurologist prescribed me Zolfresh 5mg (OD.HS). Zolfresh reduced my agitation and anger but increased my sleep. My question is whether Anger is normal in Epilepsy and how to overcome this anger. Here to mention that I practice meditation regularly.
Dr. Jyoti Kapoor Madan
Psychiatry
Zolpidem is a sleep inducer with high addictive potential. If agitation and anger are not a part of your personality, the genesis of it needs to be explored and understood. It may happen in depression, anxiety, mood disorders, substance use disorders, psychotic disorders or impulse control disorders etc. Anger management is aimed at identifying the triggers and the thought patterns behind this response. You can start by identifying what makes you angry and why and then start analysing your perceptions. You may see a psychotherapist/psychiatrist to guide you. Some anger issues are biological impulse control issues and one needs medicines to treat them. Treatment of primary psychiatric conditions like depression, anxiety and psychosis also mitigates anger.
Quel 400mg Tablet SR helps to correct chemical imbalances in the brain. It acts on various chemical messengers in the brain like dopamine and serotonin. It prevents the excessive activity of dopamine, helping to treat symptoms of schizophrenia and mania.
Is Quel 400mg Tablet SR a sleeping pill?
Quel 400mg Tablet SR can make you feel sleepy, but it is not used as a sleeping pill. Quel 400mg Tablet SR is approved for the treatment of symptoms of schizophrenia. It prevents as well as treats episodes of mania and depression in bipolar disorder. It is also used with other medicines to treat depression.
How long does Quel 400mg Tablet SR take to work?
You may start seeing an improvement within a week of starting Quel 400mg Tablet SR but full benefits may take about 4-6 weeks to appear.
Is Quel 400mg Tablet SR good for anxiety?
Quel 400mg Tablet SR has not been approved for the treatment of anxiety; however, your doctor may prescribe it for anxiety. Some studies suggest its use in post-traumatic stress disorder, generalized anxiety disorder, and anxiety associated with mood disorders.
What should I avoid while taking Quel 400mg Tablet SR?
Quel 400mg Tablet SR can cause drowsiness. So, do not drive, operate machinery or do anything dangerous until you know how Quel 400mg Tablet SR affects you. Do not drink alcohol while taking Quel 400mg Tablet SR as it may worsen the drowsiness. Avoid getting dehydrated or over-exposure to heat.
Can I stop taking Quel 400mg Tablet SR if I am better now?
No, you should not stop taking Quel 400mg Tablet SR without consulting your doctor. Suddenly stopping it may cause nausea, vomiting, headache, diarrhea, dizziness, irritability and inability to sleep. If you feel better, consult your doctor who will gradually reduce the dose before completely stopping it.
Can Quel 400mg Tablet SR cause weight gain?
Yes, weight gain is a common side effect of Quel 400mg Tablet SR. If you feel you are gaining weight, consult your doctor or a nutritionist who will suggest you a diet and some exercise to help you manage your weight.
How should Quel 400mg Tablet SR be taken?
Take Quel 400mg Tablet SR exactly as advised by your doctor. Do not split, chew or crush the tablets. Swallow the tablet whole with a glass of water. Do not take it with food. It is advised to take this medicine for at least one hour before a meal or at bedtime. Do not take grapefruit while taking Quel 400mg Tablet SR as it may affect the working of this medicine.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Stahl SM, editor. Quetiapine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 575-81.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1181-84.
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Quetiapine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
Quetiapine fumarate [Prescribing Information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2013. [Accessed 20 Feb. 2024] (online) Available from:
Country of origin: India Expires on or after: November, 2025
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