Rafinlar 50mg Capsule is used in the treatment of malignant melanoma, a type of skin cancer. Rafinlar 50mg Capsule works by blocking abnormal proteins that cause cancer cells to grow, helping to slow or stop tumor growth. It may also treat other conditions as determined by the doctor.

Rafinlar 50mg Capsule should be taken at least 1 hour before or 2 hours after a meal in the dose as advised by the doctor. The duration of treatment varies based on your response to the treatment. Your doctor may advise regular eye examinations while taking this medicine, as this medicine can cause eye problems. You must inform the doctor if you experience eye irritation, blurred vision, eye pain, or other vision changes during your treatment.

The most common side effects of Rafinlar 50mg Capsule include headache, joint pain, and hair loss. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is a very strong medicine, and some people may develop serious side effects while taking it.

Rafinlar 50mg Capsule may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Inform your doctor if you notice unusual bleeding or bruising, lack of energy, loss of appetite, or yellowing of eyes. Your doctor will advise you to have regular blood tests to check for these.

Before taking Rafinlar 50mg Capsule, tell your doctor if you have liver or kidney problems or are taking any medicines to treat infections. Many other drugs can affect or be affected by this medicine, so let your doctor know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment with this drug is important to avoid pregnancy.

Uses of Rafinlar Capsule

Treatment of Malignant melanoma

Benefits of Rafinlar Capsule

In Treatment of Malignant melanoma

Malignant melanoma is a type of skin cancer that develops in melanocytes, the cells that produce the pigment called melanin. Melanin is the pigment that gives the skin its color. Malignant melanoma is the most deadly and aggressive kind of skin cancer. Rafinlar 50mg Capsule sticks to the genetic code, called DNA, of the cancer cells and kills them. It also prevents their growth and further spread, which help treat cancer.

Side effects of Rafinlar Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Rafinlar

Diarrhea
Fever
Hyperkeratosis
Nausea
Chills
Headache
Palmar-plantar erythrodysesthesia syndrome
Hair loss
Joint pain
Cough
Muscle pain
Swelling

How to use Rafinlar Capsule

Take this medicine in the dose and duration as advised by your doctor. Rafinlar 50mg Capsule is to be taken empty stomach.

How Rafinlar Capsule works

Rafinlar 50mg Capsule is an anti-cancer medication. It works by blocking the activity of BRAF, a mutated protein that regulates cell growth. A BRAF mutation enables cells to divide at an abnormal rate and grow into a melanoma tumor. Rafinlar 50mg Capsule blocks this protein and helps control the spread of melanoma with this mutation.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Rafinlar 50mg Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Rafinlar 50mg Capsule during pregnancy is not available. Please consult your doctor.

Breast feeding

UNSAFE

Rafinlar 50mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Rafinlar 50mg Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CAUTION

Rafinlar 50mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Rafinlar 50mg Capsule may be needed. Please consult your doctor.

Liver

CAUTION

Rafinlar 50mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Rafinlar 50mg Capsule may be needed. Please consult your doctor.

What if you forget to take Rafinlar Capsule?

If you miss a dose of Rafinlar 50mg Capsule, contact your doctor as soon as possible. They will advise you on how to proceed, which may include rescheduling the missed dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

Take it on an empty stomach, at least 1 hour before or 2 hours after a meal.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for the next 4 months after you stop taking it.
Inform your doctor if you get headaches or stomachaches, or if you notice blood in your urine or stools.
Get regular eye examinations while taking this medicine. Inform your doctor if you get eye irritation, blurred vision, eye pain, or other vision changes during your treatment.
Inform your doctor if you develop symptoms of liver damage, such as abdominal pain, loss of appetite, darkened urine, or yellowing of the eyes or skin.
Rafinlar 50mg Capsule is used alone or in combination with other medicines to treat a type of skin cancer called melanoma.
Take it on an empty stomach, at least 1 hour before or 2 hours after a meal.
Do not drive or do anything requiring concentration until you know how it affects you.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for 4 months after you stop taking it.
Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
Get regular eye examinations while taking this medicine. Inform your doctor if you get eye irritation, blurred vision, eye pain or other vision changes during your treatment.
Inform your doctor if you develop symptoms of liver damage such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.

Fact Box

Chemical Class

Sulfanilide Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

BRAF inhibitor

Interaction with drugs

Taking Rafinlar with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Regorafenib (Oral Route) Severe

Do not consume Regorafenib with Dabrafenib. Dabrafenib may reduce blood levels of Regorafenib.

Tofacitinib (Oral Route) Severe

Do not consume Tofacitinib with Dabrafenib. Dabrafenib may reduce blood levels of Tofacitinib.

Ulipristal acetate (Oral Route) Severe

Do not consume Ulipristal acetate with Dabrafenib. If Ulipristal acetate is essential, ensure a gap of At least 4 weeks after discontinuing Dabrafenib. Please consult your doctor. ... More

Pazopanib (Oral Route) Severe

Do not consume Pazopanib with Dabrafenib. Dabrafenib may reduce blood levels of Pazopanib.

Apalutamide (Oral Route) Severe

Concurrent use should be avoided. Please consult with your doctor. Apalutamide may increase the metabolism of Dabrafenib.

View all drug interactions

Patient concerns

Brain star tablet for which disice

Dr. Vikas Sharma

Neurology

For neuroleptic malignant syndrome

if any one detect with melanoma is it sure that he/she gonna die after 5 or 10 year

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

No if melanoma is localized it can be removed by surgery

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Dabrafenib mesilate [EMC SmPC. Surrey, UK: Novartis Europharm Limited; 2024. [Accessed 06 May 2025] (online) Available from:
Dabrafenib [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals; 2017. [Accessed 06 May 2025] (online) Available from:
Dabrafenib [Prescribing Information]. New Jersey, USA: Novartis Pharmaceuticals Corporation; 2025. [Accessed 25 Feb. 2025] (online) Available from:

Marketer details

Name: Novartis India Ltd

Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Country of origin: United kingdom
Expires on or after: March, 2027

A licensed vendor partner from your nearest location will deliver Rafinlar 50mg Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India