Rafinlar 50mg Capsule

Dabrafenib (50mg)

Genuine

Authenticity Assured

Prescription

required

Rafinlar 50mg Capsule is used in the treatment of malignant melanoma, a type of skin cancer. Rafinlar 50mg Capsule works by blocking abnormal proteins that cause cancer cells to grow, helping to slow or stop tumor growth. It may also treat other conditions as determined by the doctor.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Mar 2026 | 11:29 AM (IST)

₹27404

₹29156

6% off

28 capsules

Get by Friday, 8 May

Gurgaon

Save more with additional offers

Pay with Amazon Pay Balance and get cashback up to Rs. 75 with minimum cashback of Rs. 15

Earn cashback up to Rs.75 with Amazon Pay Later

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Pay with Amazon Pay Balance and get cashback up to Rs. 75 with minimum cashback of Rs. 15

Earn cashback up to Rs.75 with Amazon Pay Later

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Get upto Rs.150 Cashback on minimum transaction of Rs.599/- with Mobikwik UPI.

Flat Rs.150 on a Min Transaction of Rs.1000.

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

General Information

Contains

Dabrafenib (50mg)

Marketer

Novartis India Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Rafinlar 50mg Capsule should be taken at least 1 hour before or 2 hours after a meal in the dose as advised by the doctor. The duration of treatment varies based on your response to the treatment. Your doctor may advise regular eye examinations while taking this medicine, as this medicine can cause eye problems. You must inform the doctor if you experience eye irritation, blurred vision, eye pain, or other vision changes during your treatment.

The most common side effects of Rafinlar 50mg Capsule include headache, joint pain, and hair loss. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is a very strong medicine, and some people may develop serious side effects while taking it.

Rafinlar 50mg Capsule may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Inform your doctor if you notice unusual bleeding or bruising, lack of energy, loss of appetite, or yellowing of eyes. Your doctor will advise you to have regular blood tests to check for these.

Before taking Rafinlar 50mg Capsule, tell your doctor if you have liver or kidney problems or are taking any medicines to treat infections. Many other drugs can affect or be affected by this medicine, so let your doctor know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment with this drug is important to avoid pregnancy.

Uses of Rafinlar Capsule

Treatment of Malignant melanoma

Benefits of Rafinlar Capsule

Treatment of Malignant melanoma
Malignant melanoma is a type of skin cancer that develops in melanocytes, the cells that produce the pigment called melanin. Melanin is the pigment that gives the skin its color. Malignant melanoma is the most deadly and aggressive kind of skin cancer. Rafinlar 50mg Capsule sticks to the genetic code, called DNA, of the cancer cells and kills them. It also prevents their growth and further spread, which help treat cancer.

Side effects of Rafinlar Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Rafinlar

Diarrhea
Fever
Headache
Hyperkeratosis
Palmar-plantar erythrodysesthesia syndrome
Hair loss
Nausea
Chills
Joint pain
Cough
Muscle pain
Swelling

How to use Rafinlar Capsule

Take this medicine in the dose and duration as advised by your doctor. Rafinlar 50mg Capsule is to be taken on an empty stomach.

How Rafinlar Capsule works

Rafinlar 50mg Capsule is an anti-cancer medication. It works by blocking the activity of BRAF, a mutated protein that regulates cell growth. A BRAF mutation enables cells to divide at an abnormal rate and grow into a melanoma tumor. Rafinlar 50mg Capsule blocks this protein and helps control the spread of melanoma with this mutation.

Quick tips

Take it on an empty stomach, at least 1 hour before or 2 hours after a meal.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for the next 4 months after you stop taking it.
Inform your doctor if you get headaches or stomachaches, or if you notice blood in your urine or stools.
Get regular eye examinations while taking this medicine. Inform your doctor if you get eye irritation, blurred vision, eye pain, or other vision changes during your treatment.
Inform your doctor if you develop symptoms of liver damage, such as abdominal pain, loss of appetite, darkened urine, or yellowing of the eyes or skin.
Rafinlar 50mg Capsule is used alone or in combination with other medicines to treat a type of skin cancer called melanoma.
Take it on an empty stomach, at least 1 hour before or 2 hours after a meal.
Do not drive or do anything requiring concentration until you know how it affects you.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for 4 months after you stop taking it.
Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
Get regular eye examinations while taking this medicine. Inform your doctor if you get eye irritation, blurred vision, eye pain or other vision changes during your treatment.
Inform your doctor if you develop symptoms of liver damage such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Rafinlar 50mg Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Rafinlar 50mg Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Rafinlar 50mg Capsule may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Rafinlar 50mg Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Rafinlar 50mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Rafinlar 50mg Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Rafinlar with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Ulipristal acetate (Oral Route)

Do not consume Ulipristal acetate with Dabrafenib. If Ulipristal acetate is essential, ensure a gap of At least 4 weeks after discontinuing Dabrafenib. Please consult your doctor.

Severe

Pazopanib (Oral Route)

Do not consume Pazopanib with Dabrafenib. Dabrafenib may reduce blood levels of Pazopanib.

Severe

Regorafenib (Oral Route)

Do not consume Regorafenib with Dabrafenib. Dabrafenib may reduce blood levels of Regorafenib.

Severe

Tofacitinib (Oral Route)

Do not consume Tofacitinib with Dabrafenib. Dabrafenib may reduce blood levels of Tofacitinib.

Severe

Apalutamide (Oral Route)

Concurrent use should be avoided. Please consult with your doctor. Apalutamide may increase the metabolism of Dabrafenib.

Frequently asked questions

What is Rafinlar 50mg Capsule used for?

Rafinlar 50mg Capsule is used to treat skin cancer (melanoma) caused by a specific gene mutation (BRAF V600E or V600K). Rafinlar 50mg Capsule by blocking the activity of BRAF, a mutated gene that regulates cell growth.

What are the serious side effects of Rafinlar 50mg Capsule?

Some rare but serious side effects of Rafinlar 50mg Capsule include new cancers (like skin cancer), heart problems (shortness of breath, swelling, fast heartbeat), bleeding issues, eye inflammation (pain, vision changes), severe skin reactions, fever with chills or low blood pressure, very high blood sugar (in diabetics) and liver or blood problems.

Can Rafinlar 50mg Capsule cure my cancer?

Rafinlar 50mg Capsule can slow cancer growth, shrink tumors, and improve survival in patients with cancer. It is often used in combination with other drugs like trametinib for better results.

How long does Rafinlar 50mg Capsule take to work?

Some patients see tumor shrinkage within a few weeks to months, but response times vary from individual to individual. Your doctor will monitor your progress through scans and blood tests.

Will Rafinlar 50mg Capsule affect my fertility?

Rafinlar 50mg Capsule may reduce fertility in both men and women. If you plan to have children, discuss fertility preservation options with your doctor before starting treatment.

What happens if I stop taking Rafinlar 50mg Capsule?

Do not stop Rafinlar 50mg Capsule without consulting your doctor. Stopping suddenly may allow the cancer to grow faster. If side effects are severe, your doctor may adjust your dose or switch treatments.

What monitoring do I need during Rafinlar 50mg Capsule treatment?

During Rafinlar 50mg Capsule treatment, doctors may regularly monitor heart function. Eye exams may be done, especially if there are vision issues. Blood sugar levels may be checked, particularly in individuals with diabetes. Liver and kidney function will also be monitored. Skin checks may be performed to look for new cancers. These tests help detect side effects early and ensure safe treatment.

Can anyone take Rafinlar 50mg Capsule?

No, Rafinlar 50mg Capsule is only for patients with a BRAF V600 mutation, confirmed by a lab test. It is not recommended for people whose tumors don’t have this mutation.

Fact Box

Chemical Class

Sulfanilides

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

BRAF inhibitor

References

Want to know more

We provide you with authentic, trustworthy and relevant information

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Vendor Details

Country of origin: United kingdom
A licensed vendor partner from your nearest location will deliver Rafinlar 50mg Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Rafinlar 50mg Capsule

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Rafinlar Capsule

Benefits of Rafinlar Capsule

Side effects of Rafinlar Capsule

How to use Rafinlar Capsule

How Rafinlar Capsule works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Ulipristal acetate (Oral Route)

Pazopanib (Oral Route)

Regorafenib (Oral Route)

Tofacitinib (Oral Route)

Apalutamide (Oral Route)

Frequently asked questions

What is Rafinlar 50mg Capsule used for?

What are the serious side effects of Rafinlar 50mg Capsule?

Can Rafinlar 50mg Capsule cure my cancer?

How long does Rafinlar 50mg Capsule take to work?

Will Rafinlar 50mg Capsule affect my fertility?

What happens if I stop taking Rafinlar 50mg Capsule?

What monitoring do I need during Rafinlar 50mg Capsule treatment?

Can anyone take Rafinlar 50mg Capsule?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests