Rafinlar 50mg Capsule
Prescription Required
Product introduction
Rafinlar 50mg Capsule is used in the treatment of malignant melanoma, a type of skin cancer. It may also be used to treat other conditions as determined by the doctor.
Rafinlar 50mg Capsule should be taken at least 1 hour before or 2 hours after a meal in the dose as advised by the doctor. The duration of treatment varies on the basis of your response to the treatment. Your doctor may advice regular eye examinations while taking this medicine. You must inform the doctor if you experience eye irritation, blurred vision, eye pain, or other vision changes during your treatment.
The most common side effects of this medicine include diarrhea, fever, nausea, and headache. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. It may lower your ability to fight infections and lead to problems with your blood, liver, or kidneys. Inform your doctor if you notice unusual bleeding or bruising, lack of energy, loss of appetite, and yellowing of eyes. Your doctor will advise you regular blood tests to check for these.
Before taking Rafinlar 50mg Capsule, tell your doctor if you have liver or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine, so let your doctor know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during the treatment with this drug is important to avoid pregnancy.
Uses of Rafinlar Capsule
Benefits of Rafinlar Capsule
In Treatment of Malignant melanoma
Malignant melanoma is a type of skin cancer that develops in melanocytes, the cells that produce the pigment called melanin. Melanin is the pigment that gives the skin its color. Malignant melanoma is the most deadly and aggressive kind of skin cancer. Rafinlar 50mg Capsule sticks to the genetic code, called DNA, of the cancer cells and kills them. It also prevents their growth and further spread, which help treat cancer.
Side effects of Rafinlar Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rafinlar
- Diarrhea
- Fever
- Nausea
- Chills
- Headache
- Joint pain
- Cough
- Muscle pain
- Swelling
How to use Rafinlar Capsule
Take this medicine in the dose and duration as advised by your doctor. Rafinlar 50mg Capsule is to be taken empty stomach.
How Rafinlar Capsule works
Rafinlar 50mg Capsule is an anti-cancer medication. It works by blocking the activity of BRAF, a mutated protein that regulates cell growth. A BRAF mutation enables cells to divide at abnormal rate and grow into a melanoma tumor.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Rafinlar 50mg Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Rafinlar 50mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Rafinlar 50mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Rafinlar 50mg Capsule may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Rafinlar 50mg Capsule is safe to use in patients with kidney disease. No dose adjustment of Rafinlar 50mg Capsule is recommended.
Liver
SAFE IF PRESCRIBED
Rafinlar 50mg Capsule is safe to use in patients with liver disease. No dose adjustment of Rafinlar 50mg Capsule is recommended.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Rafinlar 50mg Capsule is used alone or in combination with other medicines to treat a type of skin cancer called melanoma.
- Take it on an empty stomach, at least 1 hour before or 2 hours after a meal.
- Do not drive or do anything requiring concentration until you know how it affects you.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for 4 months after you stop taking it.
- Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
- Get regular eye examinations while taking this medicine. Inform your doctor if you get eye irritation, blurred vision, eye pain or other vision changes during your treatment.
- Inform your doctor if you develop symptoms of liver damage such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.
- Rafinlar 50mg Capsule is used alone or in combination with other medicines to treat a type of skin cancer called melanoma.
- Take it on an empty stomach, at least 1 hour before or 2 hours after a meal.
- Do not drive or do anything requiring concentration until you know how it affects you.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for 4 months after you stop taking it.
- Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
- Get regular eye examinations while taking this medicine. Inform your doctor if you get eye irritation, blurred vision, eye pain or other vision changes during your treatment.
- Inform your doctor if you develop symptoms of liver damage such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.
Fact Box
Chemical Class
Sulfanilide Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
BRAF inhibitor
Interaction with drugs
Taking Rafinlar with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Dabrafenib may reduce blood levels of Regorafenib.
Do not consume Regorafenib with Dabrafenib.
Dabrafenib may reduce blood levels of Tofacitinib.
Do not consume Tofacitinib with Dabrafenib.
Dabrafenib may reduce the efficacy of Ulipristal acetate.
Do not consume Ulipristal acetate with Dabrafenib. If Ulipristal acetate is essential, ensure a gap of At least 4 weeks a
Dabrafenib may reduce blood levels of Pazopanib.
Do not consume Pazopanib with Dabrafenib.
Dabrafenib may reduce blood levels of Lemborexant.
Do not consume Lemborexant with Dabrafenib.
Patient concerns
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Dabrafenib mesilate. Surrey, UK: Novartis Europharm Limited; 2013 [revised 20 Feb. 2019]. [Accessed 26 Mar. 2019] (online) Available from:
- Dabrafenib. East Hanover, New Jersey: Novartis Pharmaceuticals; 2013 [revised Jun. 2017]. [Accessed 26 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Marketer details
Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Country of origin: United kingdom
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₹27196
Inclusive of all taxes
MRP₹28300 4% OFF
28.0 capsules in 1 bottle
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