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Razumab 0.5mg Injection

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 07 Apr 2026 | 02:54 PM (IST)
Razumab 0.5mg Injection is used for the treatment of eye diseases which are caused by diabetes, macular degeneration, and macular swelling. It reduces the abnormal growth and leakage of blood vessels in the eye that can cause vision loss.
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General Information

Contains

Ranibizumab (0.5mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Razumab 0.5mg Injection image
Razumab 0.5mg Injection image

Product introduction

Razumab 0.5mg Injection is administered directly into the eyeball by an eye specialist. You should not self administer this medicine at home. The common side effects include conjunctival hemorrhage, eye pain, eye floaters, increased intraocular pressure, and eye inflammation.

However, if you experience these side effects for a longer duration or any other symptoms which you think may be due to this medicine, please inform your doctor. It is not advised to drive after administration of this injection as it may cause blurring of vision.

Uses of Razumab Injection

Benefits of Razumab Injection

Diabetic eye disease
Diabetic eye disease occurs when high blood sugar damages the blood vessels in the retina, leading to vision problems and even blindness if untreated. Razumab 0.5mg Injection helps protect the retina and reduce vision loss by addressing swelling and leakage in the eye. It supports clearer vision and helps individuals maintain their ability to read, work, and move around independently.
Wet age-related macular degeneration
Wet age-related macular degeneration (AMD) is an eye condition that affects central vision, making it hard to see fine details, read, or recognize faces. Razumab 0.5mg Injection helps reduce the growth of abnormal blood vessels in the eye and limits further damage to the retina. It helps preserve and, in some cases, improve vision, supporting independence and a better quality of life for older adults.
Macular edema due to retinal vein occlusion
Macular edema due to retinal vein occlusion causes swelling in the central part of the retina, leading to blurry or distorted vision. Razumab 0.5mg Injection helps reduce the swelling and improve visual clarity. It allows for sharper sight and greater ease in performing everyday tasks, improving overall visual comfort and stability.

Side effects of Razumab Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Razumab
  • Conjunctival hemorrhage
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Eye pain
  • Intraocular inflammation
  • Eye irritation
  • Increased lacrimation
  • Eyelid inflammation
  • Ocular hyperemia
  • Retinal disorder
  • Maculopathy
  • Eye discomfort
  • Posterior capsule opacification
  • Injection site hemorrhage
  • Nasopharyngitis (inflammation of the throat and nasal passages)
  • Increased intraocular pressure
  • Foreign body sensation in eyes
  • Blurred vision
  • Nausea
  • Dry eye
  • Eye itching
  • Cataract
  • Vitreous floaters
  • Vitreous detachment
  • Joint pain
  • Anemia (low number of red blood cells)

How to use Razumab Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Razumab Injection works

Razumab 0.5mg Injection is an anti-angiogenic medication. It works by blocking a protein called vascular endothelial growth factor (VEGF). This stops the growth and leakage of abnormal blood vessels in the eye(s) that may cause vision loss.

All substitutes for Razumab 0.5mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • It may cause temporary visual disturbances. Don't drive or do anything that requires mental focus until you know how Razumab 0.5mg Injection affects you.
  • Inform your doctor if you experience increased eye pain and redness, blurred or decreased vision, or increased sensitivity to light.
  • Wear sunglasses if your eyes feel sensitive to light
  • Use eye drops if they are prescribed to you by your doctor.
  • Ask your doctor if you should avoid any particular activities.
  • Try to rest your eyes as much as possible (for at least a few hours).

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Razumab 0.5mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Razumab 0.5mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Razumab 0.5mg Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Razumab 0.5mg Injection may cause temporary visual disturbances. Do not drive until your vision is clear.
Kidney

Kidney

SAFE IF PRESCRIBED
Razumab 0.5mg Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver

Liver

SAFE IF PRESCRIBED
Razumab 0.5mg Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Razumab with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Etoricoxib (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Moderate

Ticagrelor (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Moderate

Diclofenac (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Moderate

Diclofenac (Injection Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Moderate

Imatinib mesylate (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.

Frequently asked questions

Razumab 0.5mg Injection is to be administered by intravitreal (into the eye) injection once a month. Your doctor will use a medicine to numb your eye before giving you the injection. You will receive this injection in a hospital or clinic setting.
Yes, some of the common side effects of Razumab 0.5mg Injection are eye redness, sensitivity to light, pain, and abnormal vision. Seek immediate medical help in such cases.
Razumab 0.5mg Injection should not be taken by individuals who are allergic to the medication or have an active eye infection.
Razumab 0.5mg Injection is recommended to be initially administered by intravitreal injection (into the eye) once a month (approximately 28 days) for up to 3 months.
After taking Razumab 0.5mg Injection:<br>a. You should not wash your face and hair or shower for 48 hours<br>b. Avoid rubbing your eyes<br>c. Avoid swimming for a week. Consult your doctor in case of any doubts<br>d. Do not wear contact lenses immediately after injection. You may wear spectacles instead<br>e. Give complete rest to your eyes and do not strain by looking at television, mobile phones, or computer screens for 1-2 days.

Fact Box

Chemical Class

Peptides

Habit Forming

No

Therapeutic Class

OPHTHAL

Action Class

Vascular Endothelial Growth Factor (VEGF) Inhibitors

References

  1. Henderer JD, Rapuano CJ. Ocular Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1794.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1196-97.
  3. Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 977.
  4. Ranibizumab. South San Francisco, California: Genentech, Inc.; 2006. [Accessed 23 Jan. 2019] (online) Available from:
  5. Ranibizumab. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2007 [revised 26 Jul. 2018]. [Accessed 04 Apr. 2019] (online) Available from:
  6. Ranibizumab. Summary of Product Characteristics. Novartis; 2023. [Accessed 10 Sep. 2025] (online) Available from:
  7. Ranibizumab. Dublin, Ireland: Novartis Europharm Ltd.; [Accessed 06 Nov. 2025] (online). Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India
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