Restat 50mg Tablet is used to treat diabetic nerve pain. Poorly controlled diabetes can eventually lead to diabetic nerve disease (neuropathy) as a complication. This medicine helps to relieve symptoms like burning pain and numbness seen in people with diabetic nerve disease.

Restat 50mg Tablet belongs to a group of medicines known as Aldose reductase inhibitors. It can be taken with or without food but you should try to take it at the same time every day. This will help you to remember to take it. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms. It may take up to 3 months to get the full benefits of this medicine, but you should keep taking it regularly. Do not stop taking it without asking your doctor, otherwise, your condition may worsen.

This medicine is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. You should also continue taking other medicines prescribed by your doctor for blood sugar control. Keeping your blood sugar levels under control will help this medication work better.

The most common side effects of this medicine include nausea, vomiting, and abnormalities in liver function tests (increased liver enzymes). Most side effects are temporary and improve as your body gets used to the medicine. Please consult your doctor if any of these bother you or do not go away.

Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Avoid any alcohol intake while taking it as this may increase the risk of developing some side effects.

Uses of Restat Tablet

Diabetic nerve pain

Side effects of Restat Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Restat

Nausea
Vomiting
Abnormal liver function

How to use Restat Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Restat 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Restat Tablet works

Restat 50mg Tablet is an aldose reductase inhibitor. It blocks the accumulation of sorbitol in cells, which has been related to causing diabetic nerve disease.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Restat 50mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Restat 50mg Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Restat 50mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Restat 50mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Restat 50mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Restat 50mg Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Restat Tablet?

If you miss a dose of Restat 50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Restat 50mg Tablet

₹9.5/Tablet

Aldonil Tablet

Zydus Cadila

₹17.7/tablet

86% costlier

Eparel 50 Tablet

Micro Labs Ltd

₹6.25/tablet

34% cheaper

Aldorace 50mg Tablet

Sun Pharmaceutical Industries Ltd

₹6.35/tablet

33% cheaper

Epalridase 50mg Tablet

East West Pharma

₹9.21/tablet

3% cheaper

Aristat 50mg Tablet

Macleods Pharmaceuticals Pvt Ltd

₹4.01/tablet

58% cheaper

View all substitutes

Quick tips

Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
If you have existing diabetic nerve disease, wear proper footwear and examine your feet every day to detect lesions early.
If you have a foot injury or open wound, avoid engaging in weight-bearing activities.

Fact Box

Chemical Class

Carboxylic acid Derivative

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Aldose Reductase Inhibitors (ARIs)

Patient concerns

Diabetic patients nerve related pain treatment

Dr. Sanjay Bhatt

Physician

Write duration of diabetes

My father age is 50.he is diabetic.latest hba1c is 6.8 .he feels some strech(light pain in nerves) in stomach nerves when he stands or while walking.this problem is from long time(7-8 mnts old).he is fine when lie down.all the abdomen reports ct scan and ultrasound are all clear. latest results of esr(28) , and D3(29.4) can u suggest what the problem can be?if u find any problem in these reports plz provide the remedy.thanks in advance.

Dr. Vikas Sharma

Neurology

Cud be diabetic neuropathy Get nerve conduction done

What's is sciatica pain and its treatment options

Dr. M. K. Ansari

Neurology

sciatica pain is pan originating in scciatic nerve. a main nerve running from your buttocks and lower back upto the foot posteriorly. treatment of sciatica pain depends upon the cause of sciatic nerve involvement. Most of the time it is prolapsed intervertebral discs at lumbar region. and treatment involves medications to sooth the nerves nerve tonics and in some cases surgical removal of the compressive pathology

Related lab tests

Glycosylated Hemoglobin

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Ramirez MA, Borja NL. Epalrestat: An aldose reductase inhibitor for the treatment of diabetic neuropathy. Pharmacotherapy. 2008;28(5):646-55. [Accessed 18 Mar. 2019] (online) Available from:
Hotta N, Akanuma Y, Kawamori R, et al. Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial. Diabetes Care. 2006;29(7):1538-44. [Accessed 27 Mar. 2017] (online) Available from:
MIMS, Malaysia. Epalrestat. [Accessed 25 Jul. 2024] (online) Available from:

Marketer details

Name: Grownbury Pharmaceuticals Pvt Ltd

Address: 28, NEW LAYAL PUR EXTN. KRISHNA NAGAR NEW DELHI DL 110051 IN , - , .

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.