Author Details
Written By
BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
19 Nov 2024 | 01:01 AM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Rifacin 300mg Capsule

Prescription Required

Product introduction

Rifacin 300mg Capsule is an antibiotic, used in the treatment of all forms of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body. It may be used alone or in combination with other medicines to fight serious infections.

Rifacin 300mg Capsule may also be given to people who are carriers (people who are infected, yet do not show any signs and symptoms of infection). It should be taken on an empty stomach, at least 30 minutes before a meal or 2 hours after a meal. It should be taken in the dose and duration as advised by the doctor. It is better to take it at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed. Stopping it early may make the infection to come back and harder to treat.

Some people may develop side effects like low blood platelets, headache, dizziness, vomiting, nausea, and fever. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or will not go away.

Before starting treatment with this medicine, you should tell your doctor if you are pregnant, breastfeeding or suffering from any liver, kidney or heart problems or if you are allergic to any medicine. You may be regularly monitored with blood tests for liver function tests while using this medicine.

Uses of Rifacin Capsule

Benefits of Rifacin Capsule

In Tuberculosis (TB)

Rifacin 300mg Capsule is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills as well as stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Rifacin Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Rifacin

  • Low blood platelets
  • Dizziness
  • Vomiting
  • Nausea
  • Fever
  • Abdominal pain
  • Skin rash
  • Hepatitis (viral infection of liver)
  • Headache
  • Chills
  • Paradoxical reactions
  • Increased aspartate aminotransferase
  • Increased alanine aminotransferase
  • Increased bilirubin in the blood

How to use Rifacin Capsule

Take this medicine in the dose and duration as advised by your doctor. Rifacin 300mg Capsule is to be taken empty stomach.

How Rifacin Capsule works

Rifacin 300mg Capsule is an antibiotic. It works by inactivating a bacterial enzyme (RNA-polymerase) which is required by bacteria to make essential proteins and to reproduce.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Rifacin 300mg Capsule.
Pregnancy
CONSULT YOUR DOCTOR
Rifacin 300mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Rifacin 300mg Capsule is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Rifacin 300mg Capsule may cause side effects which could affect your ability to drive.
You may feel dizzy or faint, have problems with vision or have other side effects that could affect your ability to drive.
Kidney
CAUTION
Rifacin 300mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Rifacin 300mg Capsule may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Rifacin 300mg Capsule in patients with liver disease. Please consult your doctor.

What if you forget to take Rifacin Capsule?

If you miss a dose of Rifacin 300mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Rifacin 300mg Capsule
₹3.55/Capsule
₹5/capsule
41% costlier
Rimactane 300mg Capsule
Novartis India Ltd
₹3.95/capsule
11% costlier
RIFAMPILA 300MG CAPSULE
Albert David Ltd
₹2.58/capsule
27% cheaper
GOCOX 300MG CAPSULE
Ipca Laboratories Ltd
₹4.33/capsule
22% costlier
Rifasol 300mg Capsule
Asoj Soft Caps Pvt Ltd
₹3.36/capsule
5% cheaper

Quick tips

  • Your doctor has prescribed Rifacin 300mg Capsule to cure your infection and improve symptoms.
  • It is best taken on an empty stomach. If you get an upset stomach, try taking it with small portions of food. 
  • Your urine, tears and other secretions may become orange-red in colour. Avoid using contact lenses since they may become discolored.
  • Tell your doctor about all other medicines you are taking as Rifacin 300mg Capsule can interact with many medicines.
  • Avoid taking hormone-based birth control methods as Rifacin 300mg Capsule may decrease their effectiveness.
  • Tell your doctor immediately if you experience unusual tiredness or loss of appetite, fever or chills.

Fact Box

Chemical Class
Macrolactams
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
RNA polymerase inhibitors- Rifamycins

Patient concerns

arrow
My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???
Dr. Rahul Yadav
Paediatrics
Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.
Extra pulmonary tuberculosis mdr tb for spinal card treatment
Dr. Sunil Sekhri
Diabetology
This needs to be examined and treated in the clinic
arrow

FAQs

Is rifampin a penicillin/amoxicillin/sulfa drug?

No. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It has a structure and mechanism of action different from penicillin or amoxicillin (amoxicillin belongs to the class of penicillin antibiotics). The chemical structure and mechanism of action of rifampin is different from sulfa drugs

Is rifampin bacteriostatic or bactericidal?

Rifampin is a bactericidal drug. It acts by blocking the activity of a bacterial enzyme called DNA-dependent RNA polymerase which essential for important life processes in the bacteria, thereby killing the bacteria

Is rifampin an inducer or inhibitor?

Rifampin is an inducer (increases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body

What is R-cin 600 used for?

R-cin 600 is a trade name for active drug rifampin 600 mg. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It is also used in the prevention of meningococcal meningitis and Haemophilus influenza infections. It may also be used in combination with other drugs to treat infections-Brucellosis, Legionnaires disease or serious staphylococcal infections

What is R-cinex/Macox plus/R-cinex 600?

R-cinex and Macox plus are trade names for a combination of active drugs rifampin and isoniazid. It is used in the treatment of tuberculosis. R-cinex 600 and Macox plus contains 600 mg of active drug rifampin and 300 mg of active drug isoniazid

Can I take rifampin with ibuprofen/acetaminophen (Tylenol)?

Rifampin has no known serious drug interaction with ibuprofen or acetaminophen (trade name: Tylenol). Inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects

Does rifampin cause weight gain/weight loss/ hair loss/ constipation/ yeast infection?

No. Changes in body weight, hair loss or triggering constipation are not among the known side effects of rifampin. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It has no known effect on causing yeast infections

Does rifampin cause headaches?

Yes. Headache is a possible side effect of rifampin

Does rifampin change urine color/turn urine orange?

Yes. Taking rifampin may change the color of your urine (skin, sweat, saliva, tears and feces) to brownish-red or orange. This effect is not harmful

Does rifampin cause liver damage?

Rifampin is safe when used at prescribed doses for the prescribed duration. Constant monitoring of liver function is important while on treatment with rifampin. Taking drugs like saquinavir, ritonavir with rifampin can cause severe liver damage. Do consult your doctor if you have any liver problem before taking rifampin.

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1550-554.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1213-14.
  3. Drugs.com. Rifampicin. [Accessed 01 Apr. 2019] (online) Available from:External Link
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 29 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Shalina Laboratories Pvt Ltd
Address: C/48/3, TTC Industrial Area, Pawane, Navi Mumbai - 400703
Country of origin: India

NOT FOR SALE
We do not facilitate sale of this product at present

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.