Safiron 100mg Tablet is a medicine used to treat Parkinson's disease. It helps to provide better control of body movements and prevents excessive shaking and stiffness. It increases the concentration of a chemical in the brain called dopamine that plays a major role in movement control.
Safiron 100mg Tablet can be taken alone or in combination with other medicines. It may be taken with or without food, but preferably take it in the morning. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor.
If you have missed a dose, take it as soon as you remember it. You should never skip any doses and try to finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it can result in confusion, stiff muscles and a high fever.
Some common side effects of this medicine include cough, involuntary muscle movemtn, fall, nausea, and insomnia (difficulty sleeping). It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is suggested to reduce/avoid a high-protein diet (eg.meat, poultry, and dairy products) while taking Safiron 100mg Tablet as it can cause unsafe high blood pressure.
You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Safiron
Cough
Flu-like symptoms
Insomnia (difficulty in sleeping)
Involuntary muscle movement
Fall
Nausea
How to use Safiron Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Safiron 100mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Safiron Tablet works
Safiron 100mg Tablet works by increasing the amount of dopamine, a chemical messenger that is needed to control movement in the brain.
Safety advice
Alcohol
UNSAFE
Safiron 100mg Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Safiron 100mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Safiron 100mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Safiron 100mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Safiron 100mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Safiron 100mg Tablet may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Safiron 100mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Safiron 100mg Tablet may be needed. Please consult your doctor.
What if you forget to take Safiron Tablet?
If you miss a dose of Safiron 100mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Safiron 100mg Tablet can be taken with or without food or as directed by your doctor.
Reduce/avoid a high-protein diet (eg.meat, poultry, and dairy products) while you are taking the medicine as it may cause an unsafe rise in your blood pressure.
Use caution while driving or doing anything that requires concentration as Safiron 100mg Tablet can make you very sleepy.
Talk to your doctor in case you develop hallucinations or other changes in your behavior.
Do not stop taking Safiron 100mg Tablet without first talking to your doctor. Sudden stopping may cause confusion, stiff muscles and a high fever.
Fact Box
Chemical Class
Carboxylic acid and derivatives
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Monoamine Oxidase-B (MAO-B) Inhibitors
Interaction with drugs
Taking Safiron with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Safinamide with Linezolid. If Safinamide is essential, ensure a gap of At least 2 weeks between taking Safinamide and Linezolid. Please consult your doctor.
Concurr... More
Do not consume Safinamide with Linezolid. If Safinamide is essential, ensure a gap of At least 2 weeks between taking Safinamide and Linezolid. Please consult your doctor.
Concurr... More
Do not consume Tetrabenazine with Safinamide. If Tetrabenazine is essential, ensure a gap of at least 2 weeks after discontinuing Safinamide. Please consult your doctor.
Concomita... More
Do not consume Safinamide with Bupropion. If Safinamide is essential, ensure a gap of at least 24 hours after discontinuing Bupropion. Please consult your doctor.
Concomitant use ... More
Do not consume Safinamide with Linezolid. If Safinamide is essential, ensure a gap of At least 2 weeks between taking Safinamide and Linezolid. Please consult your doctor.
Concurr... More
Use Dhanadanayanadi kashayam 15ml twice a day with 15 ml water before food and Zandopa 10 grams twice a day witk milk after food and Tab Dhanvantari Vati 1-0-1 after food for 2 months
My mother suffering from Parkinson disease from 7 year , any affective medicine ?? Both hand and leg is shaking ,hardly stand up from bed himself, using parking tablet, syndopa plus and parkitidin
Dr. Saurav Arora
Homeopathy
Dear sir Parkinson's can only be managed with Homeopathy. There are few medicines which are used to improve quality of life and decrease disease progression
At times my fingers shiver when I hold cup, paper etc it's subconscious as in I do not notice it person Accompanying me notices I have no other health issues. Does this indicate Parkinson's disease? How is it diagnosed?
Is there have any medicine 4 PD Hi sir ,good afternoon My father is suffering from Parkinson's disease since last 3years. Recently he is taking syndopa plus revemer 3,Ropark 25 and amantrel I am not getting any positive results
Hi my mom had Parkinson's disease but didn't get any operation but using tablets syndopa last night she take another tablet of pain killer with it by the morning my mom to full shivering of hands and legs so what do u suggest to do?
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References
Blair HA, Dhillon S. Safinamide: A Review in Parkinson's Disease. CNS Drugs. 2017;31(2):169-176. [Accessed 01 Apr. 2020] (online) Available from:
Safinamide [FDA Label]. Louisville, KY: US WorldMeds, LLC; 2017. [Accessed 01 Apr. 2020] (online) Available from:
Safinamide [Prescribing Information]. Louisville, KY: US WorldMeds, LLC; 2017. [Accessed 20 Feb. 2024] (online) Available from:
Marketer details
Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Country of origin: India
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