


Safiron 100mg Tablet
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 07 Apr 2026 | 02:54 PM (IST)




₹219
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General Information



Product introduction
Safiron 100mg Tablet can be taken alone or in combination with other medicines. It may be taken with or without food, but preferably take it in the morning. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor.
If you have missed a dose, take it as soon as you remember it. You should never skip any doses and try to finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it can result in confusion, stiff muscles and a high fever.
Some common side effects of this medicine include involuntary muscle movement, fall, nausea, and insomnia (difficulty sleeping). It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is suggested to reduce/avoid a high-protein diet (eg.meat, poultry, and dairy products) while taking Safiron 100mg Tablet as it can cause unsafe high blood pressure.
You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it.
Uses of Safiron Tablet
Benefits of Safiron Tablet
Parkinson's disease is a progressive brain disorder that affects movement, causing symptoms like tremors, stiffness, slowed movements, and balance problems. Safiron 100mg Tablet helps improve movement control and reduces symptoms such as stiffness and slowness, making daily activities easier and improving overall quality of life for people living with the condition.
Side effects of Safiron Tablet
- Involuntary muscle movement
- Fall
- Nausea
- Insomnia (difficulty in sleeping)
How to use Safiron Tablet
How Safiron Tablet works
All substitutes for Safiron 100mg Tablet
Quick tips
- Safiron 100mg Tablet can be taken with or without food or as directed by your doctor.
- Reduce/avoid a high-protein diet (eg.meat, poultry, and dairy products) while you are taking the medicine as it may cause an unsafe rise in your blood pressure.
- Use caution while driving or doing anything that requires concentration as Safiron 100mg Tablet can make you very sleepy.
- Talk to your doctor in case you develop hallucinations or other changes in your behavior.
- Do not stop taking Safiron 100mg Tablet without first talking to your doctor. Sudden stopping may cause confusion, stiff muscles and a high fever.
- Safiron 100mg Tablet can be taken with or without food or as directed by your doctor.
- Reduce/avoid a high-protein diet (eg.meat, poultry, and dairy products) while you are taking the medicine as it may cause an unsafe rise in your blood pressure.
- Use caution while driving or doing anything that requires concentration as Safiron 100mg Tablet can make you very sleepy.
- Talk to your doctor in case you develop hallucinations or other changes in your behavior.
- Do not stop taking Safiron 100mg Tablet without first talking to your doctor. Sudden stopping may cause confusion, stiff muscles and a high fever.
Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver
Safiron 100mg Tablet should not be used in severe liver impairment.
Interaction with drugs
Bupropion (Oral Route)
Linezolid (Oral Route)
Linezolid (Injection Route)
Linezolid (Oral Route)
Linezolid (Oral Route)
Frequently asked questions
Fact Box
Chemical Class
Habit Forming
Therapeutic Class
Action Class
References
- Blair HA, Dhillon S. Safinamide: A Review in Parkinson's Disease. CNS Drugs. 2017;31(2):169-176. [Accessed 01 Apr. 2020] (online) Available from:
- Safinamide methansulfonate [EMC SmPC]. Chichester, West Sussex: Profile Pharma Limited; 2015 [revised 19 Sep. 2019]. [Accessed 01 Apr. 2020] (online) Available from:
- Safinamide [FDA Label]. Louisville, KY: US WorldMeds, LLC; 2017. [Accessed 01 Apr. 2020] (online) Available from:
- Safinamide [Prescribing Information]. Louisville, KY: US WorldMeds, LLC; 2017. [Accessed 20 Feb. 2024] (online) Available from:
- Safinamide mesylate. Rockville, MD: MDD US Operations, LLC; 2025. [Accessed 28 Jan. 2026] (online). Available from:




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