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Product introduction

Samivio Tablet is a medicine used for the treatment of liver disease associated with reduced bile formation (intrahepatic cholestasis). It protects the liver cells from toxins and helps the liver to perform its normal functions.

Samivio Tablet may be taken with or without food. The dose will depend on the severity of your condition and your body weight. It is best swallowed whole, but you may need to break them to get the correct dose. This medicine needs to be taken regularly to get the most benefit and you may have to take it for several months or longer, so try to get into a routine. Keep using it as prescribed even if your symptoms disappear.

Use of this medicine may cause some common side effects such as headache, dizziness, vomiting, upset stomach, diarrhea, constipation, and insomnia. Not everyone gets side effects. If you are worried about them, or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment. Drink enough water or fluids to stay hydrated in case of severe diarrhea and constipation.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy, or breastfeeding. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor, all other medicines you are taking. Avoid drinking alcohol as it might increase side effects.


Uses of Samivio Tablet


Side effects of Samivio Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Samivio

  • Headache
  • Dizziness
  • Vomiting
  • Upset stomach
  • Diarrhea
  • Constipation
  • Insomnia (difficulty in sleeping)

How to use Samivio Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Samivio Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Samivio Tablet works

Samivio Tablet contains S-Adenosyl L-Methoinine Disulfate Tosylate, also known as SAMe, a nutritional supplement, that can restore Glutathione concentrations in the liver and also improves liver damage. SAMe is also involved in many biochemical reactions in the human body that regulate the growth, death and differentiation of hepatocytes (liver cells). Because liver function is compromised in people suffering from liver disease, supplementation with Samivio Tablet is beneficial.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Samivio Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Samivio Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Samivio Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Samivio Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Samivio Tablet in patients with kidney disease. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Samivio Tablet is safe to use in patients with liver disease. No dose adjustment of Samivio Tablet is recommended.

What if you forget to take Samivio Tablet?

If you miss a dose of Samivio Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Samivio Tablet
₹89.9/Tablet
Samford 400 Tablet
Medford Pharmaceuticals
₹82.3/tablet
8% cheaper
Asmymax 400mg Tablet
Radicool Pharmaceutical Pvt Ltd
₹67.7/tablet
25% cheaper
S Deno 400mg Tablet
Winsome Bioceuticals
₹58.7/tablet
35% cheaper
Livopam 400 Tablet
Pamasha Pharmaceuticals Private Limited
₹64.2/tablet
29% cheaper
Mednosam 400 Tablet
Medvik Pharmaceuticals Pvt Ltd
₹77.6/tablet
14% cheaper

Quick tips

  • Samivio Tablet is prescribed for the treatment of liver disease.
  • Seek immediate medical attention if you have difficulty breathing after taking the drug.
  • Samivio Tablet may interfere with surgery. Its use should be discontinued at least two weeks prior to surgery.
  • Avoid smoking and drinking as it further degrades liver functioning.
  • You will be regularly monitored for blood creatinine and blood/urine urea levels while on treatment with Samivio Tablet.

Fact Box

Chemical Class
5'-deoxy-5'-thionucleosides
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Hepatoprotectives

Patient concerns

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Fatty liver disease with enlarged liver
Dr. Aanchal Maheshwari
Ayurveda
Take cytozen capsule twice, lavanbhasksr churan half spoon twice
Liver disease due to fatty liver
Dr. Deepak Kumar Soni
Ayurveda
Hi kindly share your reports
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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Guo T, Chang L, Xiao Y, et al. S-adenosyl-L-methionine for the treatment of chronic liver disease: A systematic review and meta-analysis. PLoS One. 2015;10(3):e0122124. [Accessed 02 Jul. 2021] (online) Available from:External Link
  2. Noureddin M, Sander-Struckmeier S, Mato JM. Early treatment efficacy of S-adenosylmethionine in patients with intrahepatic cholestasis: A systematic review. World J Hepatol. 2020;12(2):46-63. [Accessed 02 Jul. 2021] (online) Available from:External Link
  3. La Renon: S-Adenosyl-L-methionine (SAMe) [Product Information]. [Accessed 25 Jul. 2024] (online) Available from: External Link

Marketer details

Name: Wellvio Healthcare Pvt Ltd
Address: 730 JMD Megapolis Sohna Road Gurugram 122018
Country of origin: India
Expires on or after: February, 2026

A licensed vendor partner from your nearest location will deliver Samivio Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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