Bilirubin Indirect

The Bilirubin Indirect test measures the indirect (unconjugated) bilirubin in the blood. This test is performed if your doctor suspects a liver disorder, like jaundice, gallstones, hepatitis, etc. It may also be done as part of a routine health checkup or liver function test to monitor your liver health. 

Bilirubin is a byproduct of broken down old or damaged red blood cells, and the type of bilirubin that goes to the liver for processing is called indirect or unconjugated bilirubin (insoluble in water). This indirect bilirubin is bound to albumin, a type of protein in the blood, that helps carry it to the liver. The liver turns the bilirubin, along with other waste products, into a fluid called bile. The bile is then passed out of your body through the intestines, and bilirubin is the pigment that gives bile its distinctive yellow color.

You may need the Bilirubin Indirect test if you experience symptoms suggestive of liver problems, such as the yellowing of the skin and eyes, dark-colored urine, belly pain, chest pain, lightheadedness, nausea, or vomiting. It may also be done to monitor jaundice and neonatal jaundice in newborns. Usually, no special preparation is required for this test; you may eat and drink as per your daily routine.

Test result ranges are approximate and may differ slightly between different labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results. The test results will help them determine your medical condition, make recommendations for lifestyle modifications such as diet and exercise, decide whether or not medication will be required to manage your liver health, and formulate your overall treatment plan.