Seton Drop is a medicine given to children to help treat nausea and vomiting. It is mainly given to treat nausea and vomiting associated with surgery, chemotherapy, radiotherapy, and stomach/intestinal infection. It also helps treat vomiting that is caused as a side effect of medicines like painkillers.
Seton Drop may be given before or after meals. To control vomiting caused due to chemotherapy, give this medicine to your child 30 minutes before the procedure. Give it 1 to 2 hours before a radiotherapy session and 1 hour before surgery to prevent your child from vomiting post these procedures. If your child expels out the medicine within 30 minutes of the intake, help your child calm down and repeat the dose. Do not double dose if it is already time for the next dose.
Seton Drop may cause some temporary side effects such as headache, constipation, diarrhea, and fatigue. These side effects usually subside once your child’s body adapts to the medicine. In case these side effects persist or become bothersome, do reach out to the doctor on a priority basis.
Let the doctor know about all the medicines your child is taking, including painkillers, antibiotics, or medicines taken to treat depression. Also, inform the doctor if your child has a history of liver problems, kidney malfunction, blockage in the gastrointestinal tract, heart problems, or allergies to any medicine, its ingredients, or a food product. This information is very important for dose alterations and for planning your child’s overall treatment.
Seton Drop blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused by cancer chemotherapy and radiation treatment (in adults and children aged 4 years and older). It is usually taken both before and after chemotherapy or radiation. This medicine helps you recover more comfortably from these treatments. It is also effective at preventing nausea and vomiting after an operation (in adults only). The dose will depend on what you are being treated for but always take this medicine as it is prescribed.
Side effects of Seton Drop in children
Seton Drop does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Seton
Constipation
Diarrhea
Fatigue
Headache
How can I give Seton Drop to my child?
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Seton Drop may be taken with or without food, but it is better to take it at a fixed time.
How Seton Oral Solution works
During radiotherapy, chemotherapy, abdominal infection, or any major surgeries, the dead cells in the body start releasing a chemical called serotonin directly into the blood. Later, this stimulates special centers in the body that are responsible for inducing vomiting in your child. Giving Seton Drop just before the procedure helps block the effect of this chemical on vomiting centers of the brain and prevents vomiting.
Safety advice
Kidney
SAFE IF PRESCRIBED
Seton Drop is safe to use in patients with kidney disease. No dose adjustment of Seton Drop is recommended.
Liver
CAUTION
Seton Drop should be used with caution in patients with liver disease. Dose adjustment of Seton Drop may be needed. Please consult your doctor. In severe liver disease, do not exceed the prescribed dose and consult your child’s doctor.
What if I forget to give Seton Drop to my child?
Do not panic. Give the missed dose as soon as you remember. However, you must skip the missed dose if it’s almost time for the next dose. Do not give a double dose and follow the prescribed dosing schedule.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Monitor temperature of Patient. If Patient has fever place a cool, damp washcloth on your child's forehead. Give your Patient a lukewarm tub bath or a sponge bath. Give a sponge bath as follows: - ? Use lukewarm water [90?F (32.2?C) to 95?F (35?C)]. Do not use cold water, ice, or rubbing alcohol, which will lower the child's body temperature too quickly. ? Sponge for 20 to 30 minutes. ? Stop if the child starts to shiver. If your child doesn't like the sponge bath or doesn't feel better after the bath, there is no need to give another one. You can use paracetamol also along with above measures to control fever till you consult Dr. will determine underlying disorders by clinical examination which range from mild conditions to the most serious of bacterial and viral illnesses and will prescribe medicines accordingly. Advice given without doing clinical examination can be imperfect or some time harmful to patient.
Seton Drop is generally given before any major surgery or before chemotherapy and radiotherapy sessions. In case your child is about to undergo any of the above procedures, the doctor may ask you to give Seton Drop to your child to prevent vomiting post-procedure. Apart from this, Seton Drop is also found useful in treating vomiting caused due to diseases of the stomach. In such a case, your child’s doctor may prescribe giving Seton Drop to your child for a few days. Stick to the dose for best results.
Q. What if my child takes too much Seton Drop?
Seton Drop is unlikely to cause harm if you give an extra dose by mistake. However, you must still speak to your child’s doctor immediately. Sometimes, excessive intake of Seton Drop can cause some serious side effects like excess sleepiness, agitation, rapid heartbeat, hypertension, flushing, dilated pupils, sweating, involuntary muscle jerk, uncontrolled eye movements, overactive reflexes, and seizures. These symptoms are collectively known as serotonin syndrome. If any of these appear, consult the doctor without any delay.
Q. How should Seton Drop be stored?
Seton Drop should be stored at room temperature, in a dry place, away from direct heat and light. Also, keep all the medicines out of the reach and sight of children to avoid any accidental intake.
Q. Can other medicines be given at the same time as Seton Drop?
Seton Drop can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Seton Drop. Also, check with your child’s doctor before giving any medicine to your child.
Q. In what conditions do I need to call my child’s doctor right away?
Call your child’s doctor immediately if your child develops symptoms of serotonin syndrome like irregular heartbeat, green-colored vomiting, inability to pass wind, pale skin and eyes, dark-colored urine, restlessness, and insomnia.
Q. My child is having a migraine and is on medication. Can I give Seton Drop along with it?
Avoid combining Seton Drop with such medicines because concomitant use of Seton Drop with medicines meant to treat depression or migraine results in serotonin syndrome. Consult your child’s doctor before giving any medicine to your child.
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References
Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.
Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285
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Children’s Minnesota. Patient & Family Education Materials: Ondansetron (Zofran). [Accessed 04 Jan. 2020] (online) Available from:
Ondansetron [Summary of Product Characteristics]. Solan, Himachal Pradesh: Cachet Pharmaceuticals PVT. LTD.; 2024. [Accessed 25 Jul. 2024] (online) Available from:
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