Sioril 100mg Tablet

Oxyphenbutazone (100mg)

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Sioril 100mg Tablet is a pain-relieving medicine. It is used to relieve pain from inflammatory conditions including joint disorders such as osteoarthritis and rheumatoid arthritis, muscle pain, gout, and fever.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 10 Apr 2026 | 10:57 AM (IST)

₹43.1 MRP ₹47.6710% off

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General Information

Contains

Oxyphenbutazone (100mg)

Marketer

Albert David Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Sioril 100mg Tablet should be taken with food. This will prevent you from getting an upset stomach. In general, you should try to use the smallest amount necessary to control your symptoms, for the shortest possible time. You should take this medicine regularly while you need it. Try not to miss doses as this will make the medicine less effective.

Some common side effects of this medicine include vomiting, nausea, indigestion, diarrhea, and loss of appetite. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

To make sure it is safe for you, before taking this medicine, let your doctor know if you have any medical conditions or disorders. You should also tell your doctor all the other medicines you re using or taking. Pregnant and breastfeeding women should consult their doctors before using this medicine.

Uses of Sioril Tablet

Pain relief

Benefits of Sioril Tablet

Pain relief
Sioril 100mg Tablet is used to relieve pain, inflammation, and swelling in conditions such as osteoarthritis, rheumatoid arthritis, muscle pain, gout, and fever. Also, it effectively relieves muscle stiffness or spasm, thereby improving muscle movement. Taking it will help you go about your daily life more easily. If the injury is severe or lasts a long time, you may also need to take painkillers or you can even consider physiotherapy. Consult a doctor if you are not sure.

Side effects of Sioril Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sioril

Loss of appetite
Vomiting
Nausea
Indigestion
Diarrhea
Heartburn

How to use Sioril Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sioril 100mg Tablet should be taken with or after food.

How Sioril Tablet works

Sioril 100mg Tablet helps relieve pain by reducing the production of substances in the body that cause pain and inflammation. This lowers swelling, stiffness, and discomfort at the affected site. This medicine controls inflammation, provides relief from pain and improves ease of movement.

Quick tips

Sioril 100mg Tablet is used to relieve pain, inflammation, and fever.
Take it with food or milk to prevent upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
Inform your doctor if you have a history of heart disease or stroke.
Avoid consuming alcohol while taking Sioril 100mg Tablet as it can increase your risk of stomach problems.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Sioril 100mg Tablet may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Sioril 100mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Sioril 100mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Sioril 100mg Tablet may cause side effects that could affect your ability to drive.

Kidney

UNSAFE

Sioril 100mg Tablet is unsafe to use in patients with kidney disease and should be avoided.

Liver

UNSAFE

Sioril 100mg Tablet is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Sioril with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Clozapine (Oral Route)

Do not consume Clozapine with Oxyphenbutazone. If concurrent use is essential, your doctor may monitor your blood cell count frequently.

Moderate

Phenytoin (Oral Route)

If concurrent use is essential, watch out for symptoms such as blurred vision, drowsiness, impaired coordination, or impairment of visual coordination, and consult your doctor if you experience them. Your doctor may monitor and adjust the doses as per the observations. Oxyphenbutazone may raise blood levels of Phenytoin.

Moderate

Penicillamine (Oral Route)

Do not consume Penicillamine with Oxyphenbutazone. If concurrent use is essential, please consult your doctor.

Moderate

Fosphenytoin (Injection Route)

Moderate

Phenytoin (Injection Route)

Fact Box

Chemical Class

1- hydroxy- 2- unsubstituted benzenoids

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's-Non-Selective COX 1&2 Inhibitors (Others)

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Albert David Ltd
Address: D' Block, 3rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (WB) / 5/11, D. Gupta Lane, Kolkata 700 050, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Sioril 100mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Sioril Tablet

Benefits of Sioril Tablet

Side effects of Sioril Tablet

How to use Sioril Tablet

How Sioril Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Clozapine (Oral Route)

Phenytoin (Oral Route)

Penicillamine (Oral Route)

Fosphenytoin (Injection Route)

Phenytoin (Injection Route)

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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