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Smulyte Oral Solution Sugar Free is a combination medicine used in the treatment of constipation and Intestine preparation before any surgery. The medicine works by drawing water into the intestines and softening the stool, which promotes bowel movements. It also helps in maintaining electrolyte balance.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 05 Aug 2026 | 01:03 AM (IST)
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200 ml Oral Solution
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Smulyte Oral Solution Sugar Free image
Smulyte Oral Solution Sugar Free image
Smulyte Oral Solution Sugar Free image
Smulyte Oral Solution Sugar Free image

Product introduction

Take Smulyte Oral Solution Sugar Free in the dose and duration as advised by the doctor. The dose you are given will depend on the severity of your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.


The medicine is usually safe with little or no side effects. However, let your doctor know if you experience any symptoms on taking the medicine. Lifestyle modifications like having a fiber-rich diet, increasing fluid intake, and regular exercise can help you to get better results.


Before taking this medicine, let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine. You should also tell your doctor if you have any liver diseases so that your doctor can prescribe a suitable dose for you. Smulyte Oral Solution Sugar Free is generally considered safe to be used during pregancy or breastfeeding.

Uses of Smulyte Oral Solution

Benefits of Smulyte Oral Solution

Treatment of Constipation
Smulyte Oral Solution Sugar Free provides relief from constipation by softening the stool, increasing its volume, and facilitating easier passage through the intestines. Use it in the exact dose and duration advised by the doctor for maximum benefits.

Side effects of Smulyte Oral Solution

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Smulyte
  • Nausea
  • Abdominal cramp
  • Bloating
  • Vomiting
  • Anal irritation
  • Stomach fullness

How to use Smulyte Oral Solution

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Smulyte Oral Solution Sugar Free may be taken with or without food.

How Smulyte Oral Solution works

Smulyte Oral Solution Sugar Free contains potassium chloride, sodium chloride, sodium bicarbonate, and polyethylene glycol. Potassium chloride works by raising potassium levels in your blood. Sodium chloride is a purified salt solution which works by replenishing salt and electrolyte levels in the body. Sodium bicarbonate is an alkalizer. It works by increasing the pH of blood and urine, thereby correcting metabolic acidosis (high acid levels in the body). It also speeds up the removal of toxic substances from the body in certain types of poisoning. In case of excessive fluid loss (such as in diarrhea), it works by replenishing salt and electrolyte levels. Polyethylene glycol works by drawing water into the intestine through osmosis, which makes the stool soft and easier to pass. It also helps clean out the intestines prior to medical procedures or examination.

Quick tips

  • Mix Smulyte Oral Solution Sugar Free freshly each time and use immediately. Do not store any leftover prepared medicine, as it may lose its effectiveness or become unsafe to consume.
  • Do not take Smulyte Oral Solution Sugar Free if you have kidney, heart problems, high blood pressure or high blood potassium level.
  • Smulyte Oral Solution Sugar Free is usually taken once a day as needed for up to 2 weeks. Take it exactly as prescribed by the doctor.
  • Take Smulyte Oral Solution Sugar Free at least 2 hours after taking other medicines, as it may interfere with the absorption of other medicines.
  • Inform your doctor if you have a history of stomach disorders such as appendicitis or a blockage in your bowel.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Smulyte Oral Solution Sugar Free. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Smulyte Oral Solution Sugar Free during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Smulyte Oral Solution Sugar Free alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Smulyte Oral Solution Sugar Free should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Smulyte Oral Solution Sugar Free should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Smulyte Oral Solution Sugar Free is used as a bowel cleanser for colonoscopy procedures, certain bowel surgeries, and other bowel examinations. It helps empty the intestines by causing watery stools, making it easier for doctors to examine the colon.
You must mix the Smulyte Oral Solution Sugar Free with lukewarm water to make 4 liters of clear solution. Drink 240 mL (about 1 glass) every 10 minutes until the full volume is consumed or your stool becomes watery and clear. The solution should never be taken as dry powder or mixed with flavored drinks unless advised by the doctor.
No. Do not take other oral medications within 1 hour of drinking the Smulyte Oral Solution Sugar Free, as they may not be absorbed properly. Inform your doctor about all medications, especially those that affect kidneys, heart rhythm, or fluid balance.
Individuals should not take Smulyte Oral Solution Sugar Free if they have intestinal blockage (ileus), bowel perforation, toxic colitis, severe kidney or heart problems, or known allergy to PEG or any of the ingredients present in Smulyte Oral Solution Sugar Free.
Yes, you may have a light breakfast and clear liquids earlier in the day before you consume Smulyte Oral Solution Sugar Free. Avoid red or purple-colored drinks, dairy, or solid foods. After starting the prep, drink only clear fluids up to 2 hours before the colonoscopy.
You may have your first bowel movement within 1 hour after drinking Smulyte Oral Solution Sugar Free. Continue drinking the solution until your stool is clear and watery, which means your bowel is fully cleaned.
Yes. Smulyte Oral Solution Sugar Free can cause loss of body fluids and essential salts, leading to dehydration, kidney problems, or irregular heartbeat. Drink plenty of clear fluids during the prep, and stop if you feel faint, dizzy, or very weak.
If you vomit and cannot keep drinking Smulyte Oral Solution Sugar Free, stop drinking temporarily. Try again after a short break. If vomiting continues, contact your doctor as you may need an alternative preparation method.

Fact Box

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Manufacturer details

Name: A)Aristo Pharmaceuticals Pvt Ltd
Address: A)Makhnumajra, P. O. Bhud, Baddi, Dist. Solan (HP)-173 205

Marketer details

Name: Aristo Pharmaceuticals Pvt Ltd
Address: Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India. / Regd, Office: 23 -A Shah Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai-400053 Maharashtra, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Smulyte Oral Solution Sugar Free. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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