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Soften 5mg Syrup

Sodium Picosulfate (5mg)
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Soften 5mg Syrup is a medicine used to treat constipation. It is a laxative and helps you empty your bowels. It works by increasing movement in the intestine and provides relief from constipation.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 20 Jan 2026 | 11:44 PM (IST)
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Soften 5mg Syrup image
Soften 5mg Syrup image

Product introduction

Soften 5mg Syrup should be taken in a dose as advised by your doctor. Take it at a fixed time at night. You should not use this medicine for more than a few days unless your doctor tells you to. Some lifestyle changes can help with constipation, for example, eating more fiber in foods such as fruit, vegetables, and cereals, drinking plenty of fluids, and taking regular exercise.


The most common side effects of taking this medicine are nausea, vomiting, hypermagnesemia, dizziness, and headache. These are usually mild and go away after a couple of days. If they persist, your doctor may suggest ways of preventing or reducing them.


Before using this medicine, you should tell your doctor if you have a blockage in your bowel, an upset stomach, or if your bowel movements have been different for more than two weeks.

Uses of Soften Syrup

Benefits of Soften Syrup

Treatment of Constipation
Constipation can cause pain, bloating, and discomfort, and relieving it can help improve daily comfort and overall quality of life. Soften 5mg Syrup is a laxative that helps make bowel movements easier by improving stool passage and relieving discomfort caused by hard or infrequent stools. Along with treatment, drinking enough water and eating fiber-rich foods such as fruits and vegetables may help prevent constipation from coming back.

Side effects of Soften Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Soften
  • Abdominal discomfort
  • Diarrhea
  • Abdominal cramp
  • Headache
  • Increased magnesium level in blood
  • Dizziness
  • Abdominal pain

How to use Soften Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Soften 5mg Syrup may be taken with or without food.

How Soften Syrup works

Soften 5mg Syrup is a laxative. It works by increasing the movement of the intestines, thereby facilitating the passage of stool.

Quick tips

  • Together with Soften 5mg Syrup, taking a fiber-rich diet containing whole grain bread and cereals, bran, fruits, and green leafy vegetables is essential to maintain healthy bowel function.
  • Avoid taking a Soften 5mg Syrup for more than 1 week, unless prescribed by the doctor, as it leads to dependency on the laxative action to produce a bowel movement.
  • Take Soften 5mg Syrup after 2 hours from other medicines, as it may interfere with the absorption of other medicines.
  • Soften 5mg Syrup should preferably be taken at bedtime because it requires 6 to 8 hours to show impact.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Soften 5mg Syrup. Please consult your doctor.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Soften 5mg Syrup is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Soften 5mg Syrup may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Soften 5mg Syrup alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Soften 5mg Syrup should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Soften 5mg Syrup in patients with liver disease.

Interaction with drugs

Taking Soften with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Chloroquine (Oral Route)

Your doctor may monitor your potassium levels closely.
Moderate

Dexamethasone (Oral Route)

Your doctor may regularly monitor your blood potassium levels during the simultaneous use of these medicines and adjust doses accordingly if necessary.
Moderate

Loperamide (Oral Route)

Your doctor may monitor your potassium levels closely.
Moderate

Azithromycin (Oral Route)

Your doctor may monitor your potassium levels closely.
Moderate

Levofloxacin (Oral Route)

Your doctor may monitor your potassium levels closely.

Frequently asked questions

Soften 5mg Syrup is used for the short-term relief of occasional constipation. It helps trigger bowel movements by stimulating the intestines.
Although the exact onset time may vary, the effect of Soften 5mg Syrup usually begins within 6 to 12 hours after taking it. That’s why it is often recommended to take it at bedtime.
No, Soften 5mg Syrup is not recommended for children under 12 years of age, unless advised by a doctor.
Although rare, serious side effects of Soften 5mg Syrup include dizziness or fainting (especially due to dehydration), severe stomach pain, electrolyte imbalance (low potassium), and allergic reactions like swelling or rash. If you experience any of these symptoms, stop the medicine and seek medical advice.
Individuals should not take Soften 5mg Syrup if they have a blocked bowel or severe stomach pain, are dehydrated, have inflammatory bowel disease, are allergic to any ingredient in the medicine, or have hereditary fructose intolerance.
No, you should not use Soften 5mg Syrup continuously for more than 5 days without consulting a doctor. Long-term use can harm your gut and cause dehydration.
No, Soften 5mg Syrup does not help with weight loss. It only causes water loss through diarrhea, which can be harmful.

Fact Box

Chemical Class

Diphenylmethanes

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Stimulant Laxatives / Purgatives

References

  1. Sodium Picosulfate [EMC SmPC]. Guildford, Surrey: Sanofi; 2005 2017. [Accessed 27 Mar 2019] (online) Available from:
  2. Sodium Picosulfate [Summary of Product Characteristics]. Kent, UK: Kent Pharma UK Limited; 2023.
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Rudolf Life Sciences Pvt Ltd
Address: Rajguru Market, Panipat, Haryana

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Soften 5mg Syrup. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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