Sulsazine 500mg Tablet is a medicine used to treat various inflammatory conditions of the joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and bowel (ulcerative colitis, Crohn’s disease).

Sulsazine 500mg Tablet is to be taken with food. This will help you prevent an upset stomach. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better. Taking it with plenty of water can help you avoid kidney problems such as kidney stones.

Using this medicine may cause some common side effects such as nausea, headache, loss of appetite, vomiting, diarrhea, and gastrointestinal discomfort. You should consult with your doctor if any of these side effects do resolve with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problem with your heart, kidneys, or liver. Also, tell your doctor about all the other medicines you are taking. Your doctor may recommend regular blood tests to check your kidney and liver functions, and blood components. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.

Uses of Sulsazine Tablet

Benefits of Sulsazine Tablet

In Treatment of Rheumatoid arthritis

Sulsazine 500mg Tablet helps treat inflammation, pain and swelling in rheumatoid arthritis by decreasing the immune system response of the patient. It is given in the dose and frequency that suits your condition. This will be decided by the doctor. You must follow your doctor’s instructions carefully and let your doctor know if you have any bothersome side effects after taking this medicine.

In Treatment of Ulcerative colitis

Ulcerative colitis is a disease of the large intestine (colon) and rectum in which the lining of the bowel becomes red and swollen. This can lead to bleeding, frequent diarrhea and abdominal pain. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You should drink plenty of fluids while taking on treatment with this medicine to make sure you stay hydrated.

In Treatment of Crohn’s disease

Crohn’s disease is a chronic (long-term) inflammatory disease of the intestines. The most common symptoms are diarrhea and pain in your abdomen. Sulsazine 500mg Tablet helps reduce the inflammation, relieve the symptoms, and prevent them from coming back.

In Treatment of Ankylosing spondylitis

Ankylosing spondylitis is a rare type of arthritis that affects the spine or larger joints. It usually starts in your lower back and can spread up to your neck or damage joints in other parts of your body. Sulsazine 500mg Tablet helps reduce pain, stiffness and swelling in your spine and joints. It helps improve flexibility and prevents disease progression. This will help you lead a better and active life.

In Treatment of Psoriatic arthritis

Psoriatic arthritis (PsA) is a type of inflammatory arthritis that affects some individuals with psoriasis, causing joint pain, swelling, and stiffness alongside skin symptoms. Sulsazine 500mg Tablet has anti-inflammatory properties that help reduce joint pain, swelling, and stiffness. This medicine can also slow down the progression of joint damage associated with PsA. Additionally, it can help improve skin symptoms in individuals with both psoriasis and arthritis.

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Side effects of Sulsazine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sulsazine

Diarrhea
Gastrointestinal discomfort
Headache
Loss of appetite
Nausea
Oligospermia (low sperm count)
Vomiting

How to use Sulsazine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sulsazine 500mg Tablet is to be taken with food.

How Sulsazine Tablet works

Sulsazine 500mg Tablet is a Disease Modifying Anti-Rheumatoid Drug (DMARD). It works by suppressing the overactivity of the immune system in autoimmune diseases and blocks the chemical messengers that cause inflammation (swelling).

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Sulsazine 500mg Tablet.

Pregnancy

SAFE IF PRESCRIBED

Sulsazine 500mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Sulsazine 500mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Sulsazine 500mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Sulsazine 500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Sulsazine 500mg Tablet may be needed. Please consult your doctor.
Regular monitoring of kidney function tests is advisable while you are taking this medicine.

Liver

UNSAFE

Sulsazine 500mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Sulsazine Tablet?

If you miss a dose of Sulsazine 500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Sulsazine 500mg Tablet

₹5.2/Tablet

Saaz Tablet

Ipca Laboratories Ltd

₹5.29/tablet

2% costlier

Salazar Tablet

Zydus Cadila

₹5.11/tablet

2% cheaper

Sulseas 500mg Tablet

Overseas Healthcare Pvt Ltd

₹5.29/tablet

2% costlier

Sulfawise 500mg Tablet

Fibovil Pharmaceuticals Pvt Ltd

₹4.95/tablet

5% cheaper

Sazo 500 Tablet

Wallace Pharmaceuticals Pvt Ltd

₹5.29/tablet

2% costlier

View all substitutes

Quick tips

Take it with food to avoid an upset stomach.
It may take 6-8 weeks for Sulsazine 500mg Tablet to work. Keep taking it as prescribed.
Drink plenty of fluids while taking Sulsazine 500mg Tablet in order to avoid kidney problems such as kidney stones.
It may cause a deficiency of folic acid. Take the supplements as suggested by the doctor.
Do not take Sulsazine 500mg Tablet if you are allergic to sulfa drugs or aspirin.
It may discolour your skin, urine, saliva and tears an orange/yellow colour. This is normal and not harmful.
Regular blood tests to monitor your liver function, kidney function, and the levels of your blood components are required while taking this medicine.
Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class

Aminosalicylic Acids Derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Non biologics

Interaction with drugs

Taking Sulsazine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Leflunomide (Oral Route) Moderate

Leflunomide may raise blood levels of Sulfasalazine. watch out for symptoms of Sulfasalazine side effects such as diarrhea, headache, loss of appetite, nausea or vomiting and cons... More

Clozapine (Oral Route) Moderate

Concurrent use may increase the risk of low blood cell counts. Your doctor may monitor your blood cell count and adjust the doses as per the observations.

Digoxin (Oral Route) Moderate

Sulfasalazine may reduce blood levels of Digoxin. Your doctor may monitor the effects of Digoxin along with your overall treatment and adjust the doses as per the observations.

Cholestyramine (Oral Route) Moderate

Sulfasalazine may increase the effect of Cholestyramine. To take Sulfasalazine, ensure a gap of 1 hour before and 6 hours after taking Cholestyramine.

Azathioprine (Oral Route) Moderate

Concurrent use may increase the risk of harmful effects on the blood, such as a decrease in blood cell counts, etc. If concurrent use is essential, your doctor may monitor blood c... More

View all drug interactions

Patient concerns

Sir/Ma'am, I feel pain in the heel of both the legs especially when I get up from the bed in the morning. After walking couple of steps, it goes away. there is no bone problem reported in the Xray report. Please guide me what could be the reason?

Dr. Mehtab Baig

Orthopaedic Physiotherapy

This is the test for rheumatoid arthritis

What is gatheya. What is it solution

Dr. Akshat Goel

Orthopaedics

It is supposed to be Rheumatoid Arthritis

FAQs

Is Sulsazine 500mg Tablet a steroid or a painkiller?

Sulsazine 500mg Tablet is neither a steroid nor a painkiller. It is an anti-inflammatory medicine. It is used to treat and manage ulcerative colitis and Crohn's disease in which the intestines become inflamed (swelling of intestines). It is also used to treat rheumatoid arthritis (painful joint disease).

What is Sulsazine 500mg Tablet and what is it used for?

Sulsazine 500mg Tablet belongs to a group of medicines called aminosalicylates. It is an anti-inflammatory disease and is used to treat bowel inflammation, diarrhea (stool frequency), rectal bleeding, and abdominal pain in patients with ulcerative colitis and Crohn’s disease. In rheumatoid arthritis, it helps prevent damage to the joints and works slowly to reduce swelling and stiffness in your joints.

I have been prescribed Sulsazine 500mg Tablet for rheumatoid arthritis. When can I expect the pain in joints to be better?

Sulsazine 500mg Tablet does not work right away. It takes about 6 to 12 weeks to deliver the full effect.You may start feeling better in 4 weeks after starting Sulsazine 500mg Tablet, but it can vary from person to person and some of the patients may notice improvement after 3 months. Consumption of medicine should not be stopped without consulting your doctor.

For how long do I need to take Sulsazine 500mg Tablet?

If you are able to tolerate Sulsazine 500mg Tablet which means the side effects do not bother you, then you have to continue Sulsazine 500mg Tablet till the disease remains in remission. It is better to take Sulsazine 500mg Tablet for the prescribed period.

Does the use of Sulsazine 500mg Tablet for the treatment of arthritis affect the kidney function?

Though it is uncommon, Sulsazine 500mg Tablet may affect your kidney function. Therefore, it is important that your kidney function remains normal before you start taking Sulsazine 500mg Tablet. If during treatment with Sulsazine 500mg Tablet your kidney functions become abnormal, you should consult your doctor.

Do I need to get any blood tests done while on Sulsazine 500mg Tablet therapy?

Your doctor will advise you blood tests to check your blood cell counts and your kidney function before starting your treatment and regularly during treatment. The tests should also be done to measure substances produced by your liver known as enzymes (liver function tests) and urine for protein and blood before you start treatment and at regular intervals.

Can Sulsazine 500mg Tablet affect my fertility?

Decreased sperm count and infertility have been reported in some males. These may disappear once Sulsazine 500mg Tablet is discontinued.

Can I take azathioprine along with Sulsazine 500mg Tablet?

You should avoid using Sulsazine 500mg Tablet with azathioprine since there are chances of decrease in blood cell count, which can be a serious side effect.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 632-33.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1295-97.
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Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:
Choi J, Fenando A. Sulfasalazine. [Updated 2022 Nov 11]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [Accessed 06 Aug. 2023]. (online) Available from:
National Health Service. Sulfasalazine. [Accessed 06 Aug. 2023]. (online) Available from:
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Marketer details

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Address: Raman Tower, 2ND FLOOR, Sanjay Place, Agra, Uttar Pradesh 282002

Country of origin: India

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