Synclar 125mg Tablet DT is an antibiotic medication. It is given to children to treat a wide range of bacterial infections targeting the ear, throat, teeth, lungs, heart, skin, and gastrointestinal tract. It also helps treat bacterial infections that can occur in children with HIV due to their weak immune systems.

Synclar 125mg Tablet DT is also effective against some infections (e.g., MAC or Mycobacterium avium complex) seen in people with reduced immunity. It stops the bacteria from growing, which helps to resolve your symptoms and cure your infection. This medicine is taken orally, preferably either one hour before or 2 hours after a meal. No antacids should be taken within 2 hours of taking this medicine. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.

Common side effects with this medicine include diarrhea, nausea, abnormal taste, indigestion, abdominal pain, headache, vomiting, and rash. These are usually temporary and subside with the completion of treatment. Consult your doctor if you find these side effects do not resolve or persist for a longer duration.

Inform your doctor if you have any previous history of allergy or heart problems before taking this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Synclar 125mg Tablet DT in children

Treatment of Bacterial infections

Benefits of Synclar 125mg Tablet DT for your child

In Treatment of Bacterial infections

Synclar 125mg Tablet DT is an antibiotic medicine that can be used to treat many different infections caused by bacteria. These include infections of the respiratory tract, ear, nose, throat, lungs, and skin. It is also effective against a bacteria known as H. pylori, which is associated with peptic ulcer disease. It stops further growth of the bacteria causing the infection and helps treat your infection.

This medicine usually makes you feel better quite quickly. However, you should continue taking it as long as it is prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant.

Side effects of Synclar 125mg Tablet DT in children

Synclar 125mg Tablet DT does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Synclar

Abdominal pain
Diarrhea
Nausea
Taste change
Abnormal liver function tests
Skin rash
Vomiting
Headache
Rash
Insomnia (difficulty in sleeping)
Abnormal taste
Dyspepsia

How can I give Synclar 125mg Tablet DT to my child?

Take this medicine in the dose and duration as advised by your doctor. Dissolve it in a glass of water before taking it. Synclar 125mg Tablet DT may be taken with or without food, but it is better to take it at a fixed time.
Avoid Synclar 125mg Tablet DT with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Synclar Tablet DT works

Synclar 125mg Tablet DT is an antibiotic. It works by stopping the bacteria from utilizing proteins that are necessary for the bacteria to survive and perform important functions. By doing so, it stops the infection-causing bacteria from growing further and prevents the infection from spreading.

Safety advice

Kidney

SAFE IF PRESCRIBED

Synclar 125mg Tablet DT is safe to use in patients with kidney disease. No dose adjustment of Synclar 125mg Tablet DT is recommended.
Synclar 125mg Tablet DT is usually considered safe to use in children with mild to moderate kidney impairment. However, in cases of severe kidney disease, dose modifications may be needed

Liver

CAUTION

Synclar 125mg Tablet DT should be used with caution in patients with liver disease. Dose adjustment of Synclar 125mg Tablet DT may be needed. Please consult your doctor.

What if I forget to give Synclar 125mg Tablet DT to my child?

Do not panic. Unless your child’s doctor has advised a specific regime for your child, you can give the missed dose as soon as you remember. Just make sure that the next scheduled dose is at least 12 hours away.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

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Clariwin 125mg Tablet DT

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Respiclar 125mg Tablet DT

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₹17.5/tablet dt

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View all substitutes

Quick tips

Your child must complete the entire course of this medicine. Stopping the medicine without completing the dose can bring back the infection or make the bacteria resistant.
Encourage your child to drink plenty of water in case diarrhea develops as a side effect.
Do not give Synclar 125mg Tablet DT to your child for cold & flu until and unless advised by the doctor. Antibiotics are antibacterial medicines and do not work for symptoms caused due to viral infections.
Only give Synclar 125mg Tablet DT to your child for their current infection. Never save medicine for future illnesses.
Stop the medicine and contact the doctor immediately if your child develops an itchy rash, facial swelling, and breathing difficulties soon after the intake.

Fact Box

Chemical Class

Macrolides

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Macrolides

Interaction with drugs

Taking Synclar with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Eplerenone (Oral Route) Life-threatening

Clarithromycin may raise blood levels of Eplerenone. Do not consume Eplerenone with Clarithromycin.

Dronedarone (Oral Route) Life-threatening

Concomitant use may affect heart rhythm and may be fatal. Do not consume Dronedarone with Clarithromycin.

Domperidone (Oral Route) Life-threatening

Concomitant use may affect heart rhythm and can be fatal. Do not consume Domperidone with Clarithromycin.

Hydroxyzine (Oral Route) Severe

Concomitant use may affect heart rhythm and can be fatal. Do not consume Hydroxyzine with Clarithromycin.

Amiodarone (Oral Route) Severe

Concurrent use may cause serious disturbance in heart rhythm. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart... More

View all drug interactions

Patient concerns

i am suffering from sever cough and cold now i am using synclar 500mg plz suggest its dosages i have taken one tablet now one one tablet or morning evening one one tab.

Dr. Pushkar Mani

Physician

once a day only

Scar on face due to bacterial infections

Dr. Atul Jain

Dermatology

Pic is not clear, plz visit for proper opinion

User feedback

What are you using Synclar Tablet DT for?

Bacterial inf*

100%

*Bacterial infections

How much was the improvement?

Excellent

67%

Average

33%

How do you take Synclar Tablet DT?

With food

100%

Please rate Synclar 125mg Tablet DT on price

Not Expensive

100%

FAQs

In what dose should I give Synclar 125mg Tablet DT to my child?

The dose of Synclar 125mg Tablet DT will be prescribed depending upon the kind of infection, its severity, and your child’s age and body weight. Hence, altering it by yourself may cause side effects or make Synclar 125mg Tablet DT ineffective. In fact, if you give the medicine in the prescribed dose, time, and way, your child may start showing improvement after a few regular doses. But, make sure to complete the full course without stopping the medicine abruptly as doing so may make your child sick again. Also, the remaining bacteria might become resistant to the Synclar 125mg Tablet DT. Thus, following the prescribed treatment course is important and stressed upon for every medicine.

What if I give an overdose of Synclar 125mg Tablet DT by mistake?

Synclar 125mg Tablet DT is unlikely to cause any harm if an extra dose is given by mistake. But, it is important to be careful because overdose may cause unwanted side effects and may even worsen your child’s condition. So, if you think you have given too much of Synclar 125mg Tablet DT to your child, it will be wise to speak to a doctor immediately.

Are there any possible serious side effects of Synclar 125mg Tablet DT?

Some serious side effects of this medicine include abnormal heart conduction (QT prolongation), allergy, diarrhea, and severe gastrointestinal infections (superinfections). Get in touch with your child’s doctor if he/she develops any of these symptoms.

Can other medicines be given at the same time as Synclar 125mg Tablet DT?

Synclar 125mg Tablet DT can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Synclar 125mg Tablet DT. Also, check with your child’s doctor before giving any medicine to your child.

Can I get my child vaccinated while on treatment with Synclar 125mg Tablet DT ?

Antibiotics usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, children taking antibiotics should not get vaccinated until they recover from the illness. As soon as your child feels better, the vaccine can be given.

Which all lab tests should my child undergo while taking Synclar 125mg Tablet DT on a long term basis?

The doctor may prescribe getting kidney function tests, liver function tests, and baseline ECG on a periodic basis to keep a check on your child’s condition.

Can Synclar 125mg Tablet DT affect my child’s digestion?

Since children have a sensitive stomach, they may develop a stomach upset while taking medicines. Moreover, taking antibiotics may kill off the good bacteria present in the digestive system along with the bad ones, increasing your child’s risk of developing stomach problems. So, in case your child is having diarrhea while on Synclar 125mg Tablet DT, do not stop the medicine course. Instead, call your child’s doctor to ask about the next steps. In some cases, the doctor may alter the dose.

My child is suffering from a muscle weakness disorder. Is it safe to give Synclar 125mg Tablet DT?

Use Synclar 125mg Tablet DT with caution in children with neuromuscular disorders like Myasthenia gravis as it may cause exacerbation of symptoms and even onset of some new symptoms.

How can the bacteria develop resistance against Synclar 125mg Tablet DT?

Using Synclar 125mg Tablet DT when your child does not need it will give the bacteria an opportunity to adapt to the medicine and develop ways to escape the medicine’s effects. This will make the medicine ineffective when your child actually needs it. Usually, when this happens, people say that the child has become resistant to the antibiotic, but in reality, it is the opposite. It is actually the bacteria that have become resistant to the treatment.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chambers HF, Deck DH. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidiones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 800-801.
Clarithromycin [FDA Label]. Barceloneta, PR: Abbott Pharmaceuticals PR Ltd.; 2012. [Accessed 06 Jan. 2020] (online) Available from:
Clarithromycin [EMC Label]. Camberley, UK: Sandoz Limited; 2009. [Accessed 06 Jan. 2020] (online) Available from:
Clinical Guidelines: Offering Information on HIV/AIDS Treatment, Prevention, and Research. [Accessed 12 Jan. 2020] (online) Available from:
Clarithromycin [Drug Label]. Jacksonville, FL: Ranbaxy Pharmaceuticals Inc.; 2007. [Accessed 06 Apr. 2024] (online) Available from:

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