Syndyma 400mg/16ml Injection
Prescription Required
Product introduction
Syndyma 400mg/16ml Injection is an anticancer medication. It is used in the treatment of cancer of colon and rectum, non-small cell lung cancer, kidney cancer, brain tumor, ovarian and cervical cancer. It helps to prevent the growth of new blood vessels that feed tumors and stops tumors from growing.
Syndyma 400mg/16ml Injection is an effective medicine, first-line option when used together with other cancer medicines. It is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. The doctor will decide your dose and duration and will check you for signs of an infusion reaction such as high blood pressure and trouble breathing. You keep taking Syndyma 400mg/16ml Injection as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking it or not. You may be advised to check blood pressure and levels of protein in urine while you are taking this medication.
The most common side effects of this medicine include rectal bleeding, taste change, and headache. Inform your doctor that you are taking this medication before undergoing any surgical procedure, as the drug has ability to lower the ability of wound healing. Other than this, it also enhances your risk of bleeding thus if you notice any unusual bleeding or bleeding consult with your doctor immediately.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.
Syndyma 400mg/16ml Injection is an effective medicine, first-line option when used together with other cancer medicines. It is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. The doctor will decide your dose and duration and will check you for signs of an infusion reaction such as high blood pressure and trouble breathing. You keep taking Syndyma 400mg/16ml Injection as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking it or not. You may be advised to check blood pressure and levels of protein in urine while you are taking this medication.
The most common side effects of this medicine include rectal bleeding, taste change, and headache. Inform your doctor that you are taking this medication before undergoing any surgical procedure, as the drug has ability to lower the ability of wound healing. Other than this, it also enhances your risk of bleeding thus if you notice any unusual bleeding or bleeding consult with your doctor immediately.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using.
Uses of Syndyma Solution for Infusion
Side effects of Syndyma Solution for Infusion
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Syndyma
- Exfoliative dermatitis
- High blood pressure
- Nosebleeds
- Protein in urine
- Decreased appetite
- Electrolyte imbalance
- Peripheral sensory neuropathy
- Breathlessness
- Thromboembolism
- Wound healing complications
- Ovarian failure
- Decreased white blood cell count (lymphocytes)
- Low blood platelets
- Mucosal inflammation
- Abscess
- Cellulitis
- Hypersensitivity
- Rectovaginal fistula
How to use Syndyma Solution for Infusion
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
How Syndyma Solution for Infusion works
Syndyma 400mg/16ml Injection is a anti-angiogenic medication. It works by blocking a protein called vascular endothelial growth factor (VEGF). This stops the formation of blood vessels that bring oxygen and nutrients to cancerous cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Syndyma 400mg/16ml Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Syndyma 400mg/16ml Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Syndyma 400mg/16ml Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Syndyma 400mg/16ml Injection may cause side effects which could affect your ability to drive.
Sleepiness and fainting have been reported with Syndyma 400mg/16ml Injection and this may impair your ability to drive.
Sleepiness and fainting have been reported with Syndyma 400mg/16ml Injection and this may impair your ability to drive.
Kidney
SAFE IF PRESCRIBED
Syndyma 400mg/16ml Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Syndyma 400mg/16ml Injection may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Syndyma 400mg/16ml Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Syndyma 400mg/16ml Injection may not be needed in these patients. Please consult your doctor.
What if you forget to take Syndyma Solution for Infusion?
If you miss a dose of Syndyma 400mg/16ml Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Syndyma 400mg/16ml Injection is an effective, first-line option when used together with other medicines for certain types of cancers such as colorectal, lung, cervical, and kidney cancers.
- Syndyma 400mg/16ml Injection is given as an infusion. Your doctor or nurse will monitor you for signs of an infusion reaction such as high blood pressure and trouble breathing.
- It can lower your wound healing ability. Inform your doctor that you are taking this medication before undergoing any surgical procedure.
- It can increase the risk of bleeding. Inform your doctor if you notice any unusual bleeding or bleeding that doesn't stop easily.
- Your doctor may regularly check your blood pressure and levels of protein in your urine while you are on Syndyma 400mg/16ml Injection.
- Syndyma 400mg/16ml Injection is an effective, first-line option when used together with other medicines for certain types of cancers such as colorectal, lung, cervical, and kidney cancers.
- Syndyma 400mg/16ml Injection is given as an infusion. Your doctor or nurse will monitor you for signs of an infusion reaction such as high blood pressure and trouble breathing.
- It can lower your wound healing ability. Inform your doctor that you are taking this medication before undergoing any surgical procedure.
- It can increase the risk of bleeding. Inform your doctor if you notice any unusual bleeding or bleeding that doesn't stop easily.
- Your doctor may regularly check your blood pressure and levels of protein in your urine while you are on Syndyma 400mg/16ml Injection.
Fact Box
Chemical Class
Monoclonal antibody (mAb)
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Vascular endothelial growth factor (VEGF) inhibitor
Patient concerns
FAQs
Q. What kinds of cancer can Syndyma 400mg/16ml Injection be used for ?
Syndyma 400mg/16ml Injection is approved for the treatment of cancer of the colon or rectum that has spread to other parts of the body. It must be given along with chemotherapy. Other types of cancers that it helps with includes certain types of lung cancer, kidney cancer, ovarian cancer, cervical cancer, and glioblastoma (a type of brain tumor).
Q. How is Syndyma 400mg/16ml Injection given?
Syndyma 400mg/16ml Injection is given as an infusion. That means you get it through a small needle in your vein or through a port, which is a device placed under your skin. Your doctor will decide your dose and duration and will monitor you for signs of an infusion reaction.
Q. How long can I take Syndyma 400mg/16ml Injection for?
You keep taking Syndyma 400mg/16ml Injection as long as your disease is controlled and your side effects are manageable. Your doctor will determine whether you should stop taking Syndyma 400mg/16ml Injection. If your cancer progresses during this initial treatment, talk to your doctor if a different chemotherapy may be an option.
Q. How Syndyma 400mg/16ml Injection works differently from chemotherapy?
Chemotherapy attacks fast-growing cells, like cancer cells. In contrast, the purpose of Syndyma 400mg/16ml Injection is to prevent the growth of new blood vessels that feed tumors. This causes the tumour to shrink, or to stop growing.
Q. Does a person taking Syndyma 400mg/16ml Injection still need chemotherapy?
Chemotherapy is still needed along with taking Syndyma 400mg/16ml Injection. It makes chemotherapy work better.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1739-40.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 955.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 142-43.
Marketer details
Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Country of origin: India
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