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Tegafi 100mg/224mg Capsule

Tegafur (100mg)+ Uracil (224mg)

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Tegafi 100mg/224mg Capsule is a prescription medicine which is a combination of two anticancer medicines that is used in the treatment of cancer of the colon and rectum. It prevents the growth and multiplication of cancer cells, thus helps in destroying the tumor.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 07 Apr 2026 | 02:54 PM (IST)

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14 capsules

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General Information

Contains

Tegafur (100mg)+ Uracil (224mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Tegafi 100mg/224mg Capsule may be taken with or without food. It should be used in the dose and duration as prescribed by your doctor. It is advised to take this medicine at a fixed time.

This medicine should not be taken more than the recommended dose. If you miss any dose, please consult your doctor. It is advised to complete the treatment without any interruption. This medicine is usually well tolerated by patients.

The common side effects of this medicine include nausea, vomiting, hair loss, low number of blood cells (anemia) and a decrease in white blood cell count. The doctor may ask you to undergo a few blood tests before or during the treatment.

Your doctor may prescribe you to undergo blood tests before or during the treatment. You may be given supplements to overcome the deficiency caused by this medicine. It is advised to add more vegetables and fruits in your diet to overcome any such deficiency.

This medicine is not safe to use in pregnancy. Inform your doctor if you are taking any other medicines or if you are breastfeeding. Inform your doctor if you are suffering from any disease. It is strictly advised not to drive or operate heavy machinery while you are on the treatment.

Uses of Tegafi Capsule

Cancer of colon and rectum

Benefits of Tegafi Capsule

Cancer of colon and rectum
Tegafi 100mg/224mg Capsule treats cancer of the colon and rectum as well as lowers the risk of developing further cancerous growths. Using this medicine helps you recover more comfortably from chemotherapy. It is usually taken for 28 days (four weeks), followed by a seven day break. The cycle is then repeated. Follow your doctor's advice strictly during the entire treatment. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

Side effects of Tegafi Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tegafi

Nausea
Vomiting
Tiredness
Mouth sore
Sore tongue
Stomach pain
Diarrhea
Loss of appetite
Decreased blood cells (red cells, white cells, and platelets)

How to use Tegafi Capsule

Take this medicine in the dose and duration as advised by your doctor. Tegafi 100mg/224mg Capsule may be taken with or without food.

How Tegafi Capsule works

Tegafi 100mg/224mg Capsule is a combination of two medicines: Tegafur and Uracil which treat cancer. They work by interfering with the growth of DNA and RNA of cancer cells by substituting their building blocks. This prevents the cancer cells from growing and multiplying.

All substitutes for Tegafi 100mg/224mg Capsule

For information purposes only. Consult a doctor before taking any medicine.

Luporal Capsule

by Lupin Ltd

₹119.4/capsule

2% costlier

Tegasted Capsule

by Halsted Pharma Private Limited

₹139.2/capsule

19% costlier

Quick tips

Tegafi 100mg/224mg Capsule is used for the treatment of cancer of the colon and rectum.
Avoid the use of antacids within 2 hours of taking this medicine.
Drink plenty of water every 24 hours after the start of the treatment.
You may be at risk of infection so try to avoid crowds or people with colds, and report fever or any other signs of infection immediately to your doctor.
To help treat/prevent mouth sores, use a soft toothbrush and rinse your mouth at least 3 times a day with saline water.
To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
Eat foods that may help reduce diarrhea and take adequate rest.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Tegafi 100mg/224mg Capsule. Please consult your doctor.

Pregnancy

UNSAFE

Tegafi 100mg/224mg Capsule is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Tegafi 100mg/224mg Capsule during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Tegafi 100mg/224mg Capsule may cause side effects that could affect your ability to drive.
Tegafi 100mg/224mg Capsule may make you tired, nauseous or have blurred vision and this may affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Tegafi 100mg/224mg Capsule in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Tegafi 100mg/224mg Capsule in patients with liver disease.

Frequently asked questions

Who should not take Tegafi 100mg/224mg Capsule?

Individuals should not take Tegafi 100mg/224mg Capsule if they are allergic to tegafur, uracil, 5-fluorouracil (5-FU), or any ingredient in the medicine. It is also not safe for children, teenagers, pregnant women, or breastfeeding mothers.

Can Tegafi 100mg/224mg Capsule cause liver damage?

Yes, Tegafi 100mg/224mg Capsule may cause serious liver problems, including hepatitis and, in rare cases, liver failure. Your doctor may run regular blood tests to check your liver function while you are taking this cancer treatment. If you notice yellowing of the skin or eyes, dark urine, or severe fatigue, seek medical help immediately.

Is diarrhea from Tegafi 100mg/224mg Capsule dangerous?

Diarrhea is a common side effect of Tegafi 100mg/224mg Capsule, but it can become dangerous if severe. If you develop persistent or watery diarrhea, you should stop the medication and contact your doctor right away, as it can lead to dehydration and require medical care.

Can Tegafi 100mg/224mg Capsule affect the heart?

Yes, Tegafi 100mg/224mg Capsule may cause heart problems in some patients, such as chest pain, irregular heartbeat, heart failure, or heart attack. If you already have a heart condition, your doctor will monitor you more closely during treatment.

Is Tegafi 100mg/224mg Capsule safe for elderly patients?

Elderly patients may be at higher risk of side effects from Tegafi 100mg/224mg Capsule because of weaker liver, kidney, or heart function. Doctors usually start older patients on the medicine with extra caution and frequent monitoring.

What are the serious side effects of Tegafi 100mg/224mg Capsule?

Serious side effects of Tegafi 100mg/224mg Capsule include unexplained bleeding or bruising, severe infection, chest pain, breathing problems, confusion, or sudden weakness. Rarely, it can cause life-threatening conditions like liver failure, severe skin reactions, or kidney failure. Contact your doctor immediately if you notice any of these.

Can Tegafi 100mg/224mg Capsule affect my blood counts?

Yes, Tegafi 100mg/224mg Capsule can lower your white blood cells, red blood cells, and platelets, which can make you more prone to infections, anemia, or bleeding. Your doctor will check your blood counts regularly during treatment.

Can I take Tegafi 100mg/224mg Capsule if I have kidney problems?

There is limited experience with Tegafi 100mg/224mg Capsule in patients with kidney problems. Your doctor may prescribe it with caution and monitor your kidney function closely. Report any swelling, decreased urine output, or unusual tiredness to your doctor.

Can Tegafi 100mg/224mg Capsule cause nervous system problems?

In rare cases, Tegafi 100mg/224mg Capsule may affect the nervous system, leading to confusion, memory loss, speech problems, unsteady walking, or nerve pain. Report these symptoms to your doctor right away.

How can Tegafi 100mg/224mg Capsule affect the skin?

Tegafi 100mg/224mg Capsule may sometimes cause skin problems like rashes, itching, eczema, or more serious reactions such as Stevens-Johnson syndrome (a rare but severe skin condition). If you develop blistering, peeling skin, or painful sores, stop the medication and seek emergency care.

Fact Box

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Related lab tests

Carcino Embryonic Antigen

References

User feedback

What are you using Tegafi Capsule for?

Cancer of colon and rectum

67%

Others

33%

How much was the improvement?

Excellent

67%

Average

33%

What were the side-effects while using Tegafi 100mg/224mg Capsule?

Vomiting

20%

Low blood platelets

20%

Weakness

20%

Loss of appetite

20%

Nausea

20%

How do you take Tegafi Capsule?

With or without food

100%

Please rate Tegafi 100mg/224mg Capsule on price

Expensive

67%

Average

33%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Tegafi 100mg/224mg Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Tegafi 100mg/224mg Capsule

Cash on delivery

Free Return

Expiry after

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Tegafi Capsule

Benefits of Tegafi Capsule

Side effects of Tegafi Capsule

How to use Tegafi Capsule

How Tegafi Capsule works

All substitutes for Tegafi 100mg/224mg Capsule

Luporal Capsule

Tegasted Capsule

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Who should not take Tegafi 100mg/224mg Capsule?

Can Tegafi 100mg/224mg Capsule cause liver damage?

Is diarrhea from Tegafi 100mg/224mg Capsule dangerous?

Can Tegafi 100mg/224mg Capsule affect the heart?

Is Tegafi 100mg/224mg Capsule safe for elderly patients?

What are the serious side effects of Tegafi 100mg/224mg Capsule?

Can Tegafi 100mg/224mg Capsule affect my blood counts?

Can I take Tegafi 100mg/224mg Capsule if I have kidney problems?

Can Tegafi 100mg/224mg Capsule cause nervous system problems?

How can Tegafi 100mg/224mg Capsule affect the skin?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Carcino Embryonic Antigen

References

User feedback

What are you using Tegafi Capsule for?

How much was the improvement?

What were the side-effects while using Tegafi 100mg/224mg Capsule?

How do you take Tegafi Capsule?

Please rate Tegafi 100mg/224mg Capsule on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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