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06 Dec 2024 | 01:06 AM (IST)

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Tepapro Injection

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Product introduction

Tepapro Injection is used in the treatment of cancers of the brain, breast, lungs, and ovaries. It is used in combination with other cancer medicine during hematopoietic progenitor cell transplantation (HPCT). It may be also used to treat other conditions, as determined by the doctor.

Tepapro Injection is generally given under the supervision of a healthcare professional. Your doctor will decide the dose and duration of the treatment based on the severity of your condition and what you are being treated for. It may take several weeks or months for you to see or feel the benefits but do not stop getting the injection unless your doctor tells you to.

The most common side effects of this medicine include decreased white blood count, anemia, low blood platelets, increased liver enzymes, increased bilirubin in the blood, mucosal inflammation, hemorrhage, diarrhea, blood in urine, and rash. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidneys, liver, and heart function during treatment with this medicine.

Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Benefits of Tepapro Injection

In Non-small cell lung cancer

Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Tepapro Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Ovarian cancer

Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Tepapro Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but has some side effects that may be bothersome. So, you should discuss the risks and benefits with your doctor.

Side effects of Tepapro Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tepapro

  • Decreased white blood cell count (neutrophils)
  • Anemia (low number of red blood cells)
  • Low blood platelets
  • Increased liver enzymes
  • Increased bilirubin in the blood
  • Mucosal inflammation
  • Hemorrhage
  • Rash
  • Diarrhea
  • Blood in urine

How to use Tepapro Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Tepapro Injection works

Tepapro Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tepapro Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Tepapro Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Tepapro Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Tepapro Injection may cause side effects which could affect your ability to drive.
It is likely that certain adverse events of Tepapro Injection are dizziness, headache, and blurred vision which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Tepapro Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Tepapro Injection may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Tepapro Injection should be used with caution in patients with liver disease. Dose adjustment of Tepapro Injection may be needed. Please consult your doctor.
Regular monitoring of liver function tests may be advised while you are taking this medicine.

What if you forget to take Tepapro Injection?

If you miss a dose of Tepapro Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Tepapro Injection
₹10499/Injection
₹11595/injection
9% costlier
Tepakin 15mg Injection
MSN Laboratories
₹18400/injection
74% costlier
Tepawel 15mg Injection
Getwell Pharma (I) Pvt Ltd
₹11200/injection
6% costlier
Therotepa 15mg Injection
Therdose Pharma Pvt Ltd
₹18900/injection
78% costlier
Thiother 15mg Injection
Therdose Pharma Pvt Ltd
₹18900/injection
78% costlier

Quick tips

  • Tepapro Injection is given as an intravenous infusion (IV infusion) under the supervisión of a doctor.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your blood cell count, platelet count and liver function.
  • It makes you feel dizzy. Do not drive or operate machinery until you know how it affects you.

Fact Box

Chemical Class
Thiophosphoric Acids Derivatives
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alkylating agent

Interaction with drugs

Taking Tepapro with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells. Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytot... More
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells. Do not consume Thiotepa from 1 day before until 1 day after taking Molgramostim. Plea... More
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells. Do not consume Thiotepa from 1 day before until 1 day after taking Sargramostim. Plea... More
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells. Do not consume Thiotepa from 14 days before until 24 days after taking Pegfilgrastim.... More
Concomitant use may increase the risk of opportunistic infections. Do not consume Natalizumab with Thiotepa.

Patient concerns

arrow
What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma
Dr. Vijay Sharnangat
Medical Oncology and Hematology
This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.
If any symtom of brest cancer if have whats the cure
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
First is confirmation of breast cancerChance of cure depends on stage of cancer
arrow

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1685.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1355-56.
  3. Thiotepa. Lugano, Switzerland: ADIENNE SA; 1959 [revised Jan. 2017]. [Accessed 27 Mar. 2019] (online) Available from:External Link
  4. Drugs.com. Thiotepa Pregnancy and Breastfeeding Warnings. [Accessed 27 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Emcure Pharmaceuticals Ltd
Address: 255/2, Hinjawadi, Pune - 411057, India
Country of origin: India

10499
Inclusive of all taxes
MRP10600  1% OFF
1.0 Injection in 1 vial
SOLD OUT
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