Tibolone 2.5mg Tablet is a female sex hormone (estrogen). This is a type of hormone replacement therapy (HRT) that is used to treat symptoms associated with menopause (hot flushes, vaginal dryness, and itching), estrogen deficiency, and thinning of bones (osteoporosis).

Tibolone 2.5mg Tablet can be taken with or without food, but better to take it at a fixed time each day for better efficacy. It should be swallowed whole with water. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine.

The most common side effects of this medicine are lower abdominal pain, abnormal hair growth, endometrial hyperplasia, vaginal discharge, breast tenderness, genital itching, vaginal bleeding, pelvic pain, cervical thickening, and weight gain. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs. If you experience any such effects, consult your doctor.

Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.

Uses of Tibolone Tablet

Side effects of Tibolone Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tibolone

Postmenopausal hemorrhage
Cervical dysplasia
Abnormal cervical smear
Vaginal yeast infection
Weight gain
Vaginal bleeding
Endometrial hyperplasia
Vaginal discharge
Pelvic pain
Breast tenderness
Genital itching
Lower abdominal pain
Abnormal hair growth

How to use Tibolone Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tibolone 2.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Tibolone Tablet works

Tibolone 2.5mg Tablet is a hormonal medication. It has effects similar to estrogen, progesterone and androgen. It substitutes for the loss of estrogen production in postmenopausal women and treats menopausal symptoms such as hot flashes, night sweats and vaginal problems. It also prevents bone loss following menopause.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Tibolone 2.5mg Tablet.

Pregnancy

UNSAFE

Tibolone 2.5mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Tibolone 2.5mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

SAFE

Tibolone 2.5mg Tablet does not usually affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Tibolone 2.5mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Tibolone 2.5mg Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Tibolone Tablet?

If you miss a dose of Tibolone 2.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Tibolone 2.5mg Tablet

₹28.71/Tablet

Sibolone Tablet

Serum Institute Of India Ltd

₹24.8/tablet

14% cheaper

Livial Tablet

Organon (India) Ltd

₹62/tablet

116% costlier

Tibofem Tablet

Cipla Ltd

₹31.29/tablet

9% costlier

Maxtib Tablet

Sun Pharmaceutical Industries Ltd

₹21.79/tablet

24% cheaper

Tivion Tablet

Aci Pharma Pvt Ltd

₹19.8/tablet

31% cheaper

Quick tips

Tibolone 2.5mg Tablet is used as a part of hormone replacement therapy to relieve symptoms of menopause such as hot flushes, vaginal dryness, depression, and night sweats.
It may also be used for preventing osteoporosis in women who have attained menopause and are at high risk of fractures.
Take it at the same time everyday to help you remember to take it.
It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.
Stop taking Tibolone 2.5mg Tablet and inform your doctor immediately if you get severe headaches, stabbing pains or swelling in one leg, and pain on breathing. These could be symptoms of a blood clot in a vein.
Ensure that you regularly check your breasts for any changes and undergo regular breast screening and cervical smear tests while on treatment with this medicine.
Do not use Tibolone 2.5mg Tablet if you have a history of blood clots and liver disease.
Tibolone 2.5mg Tablet is used as a part of hormone replacement therapy to relieve symptoms of menopause such as hot flushes, vaginal dryness, depression, and night sweats.
It may also be used for preventing osteoporosis in women who have attained menopause and are at high risk of fractures.
Take it at the same time everyday to help you remember to take it.
It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.
Stop taking Tibolone 2.5mg Tablet and inform your doctor immediately if you get severe headaches, stabbing pains or swelling in one leg, and pain on breathing. These could be symptoms of a blood clot in a vein.
Ensure that you regularly check your breasts for any changes and undergo regular breast screening and cervical smear tests while on treatment with this medicine.
Do not use Tibolone 2.5mg Tablet if you have a history of blood clots and liver disease.

Fact Box

Chemical Class

Oxosteroids

Habit Forming

Therapeutic Class

GYNAECOLOGICAL

Action Class

Estrogens

Patient concerns

I have been told by doctors I have cystitis also simple cyst in right ovary . What should I be doing its been two years I have this issue

Dr. Megha Tuli

Obstetrics and Gynaecology

Hi PATIENT hormone therapy helps with cysts. Ask your doctor for a hormone replacement.

Having urine burning problem past month. with the homeop medicine 70% relief i got. now i stopped medicine to have. five year back hystectomy done overies still remain. due to computer work eyes get dried and tired. shoulders also pain. past 1.7 year back pain started. some time hot flashes also come suddenly. all blood investigation and u/s are normal. as per dr. advise take sweet less. hair fall are more. no dandruff.

Dr. Megha Tuli

Obstetrics and Gynaecology

It is normal to have hot flashes and these post menopausal symptoms after hysterectomyYou can take hormone therapy if you want however symptoms will recurrent when you stop treatment

FAQs

Does Tibolone 2.5mg Tablet contain progesterone?

It is a synthetic medicine which is used to fulfill the functions of the normal sex hormones like estrogen and progesterone in the body of women. On taking Tibolone 2.5mg Tablet it is broken down in our body and functions like estrogen, progesterone and a part to testosterone (male sex hormone). It is prescribed to compensate for the loss of estrogen production in postmenopausal women and decrease the menopausal symptoms.

Is Tibolone 2.5mg Tablet a combined HRT?

Yes, Tibolone 2.5mg Tablet is a type of medicine used in hormone replacement therapy (HRT) which is given to post-menopausal women. It is given to prevent the adverse effects on various organs and systems due to decrease in the levels of hormones like estrogen and progesterone. It shows positive effect on different tissues in the body, such as brain, vagina, and bones.

Can Tibolone 2.5mg Tablet be taken during pregnancy?

No, Tibolone 2.5mg Tablet is not to be taken in pregnancy or if you are planning to get pregnant. In case you become pregnant during treatment with this medication you should contact your doctor and the medicine should be withdrawn immediately.

Does Tibolone 2.5mg Tablet help in elevating mood?

Yes, this medicine has shown positive results when given to postmenapausal women as a substitute for the hormonal deprivation. Patients have experienced reduction in the menopausal complaints like persistent fatigue, blunted motivation, and loss of sexual desire. However, consult the doctor regarding any query for your mood problems before you start taking this medication.

Can Tibolone 2.5mg Tablet help in osteoporosis?

Yes, Tibolone 2.5mg Tablet can help in osteoporosis. After menopause some women become prone to develop fragile bones called osteoporosis which can lead to an increased risk of fractures. Tibolone 2.5mg Tablet acts as a replacement for the female sex hormones when given in the post-menopausal phase. These hormones help in increasing bone density. Therefore, taking Tibolone 2.5mg Tablet can prevent bone loss and osteoporosis. Do consult your doctor before starting this medication as you might need other supplemental medications to treat osteoporosis.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Tibolone. London, UK: ADVANZ Pharma; 2016 [revised 26 Apr. 2016]. [Accessed 23 Jan. 2019] (online) Available from:
Tibolone. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2009 [revised 22 Mar. 2016] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
Tibolone [EMC SmPC]. London, UK: Organon Pharma (UK) Limited; 2023. [Accessed 08 May 2024] (online) Available from:

Marketer details

Name: Cipla Ltd

Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.