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Topisone G Cream

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 12 Mar 2026 | 12:45 PM (IST)
Topisone G Cream is a combination medicine used in the treatment of skin infections. It works by killing microorganisms that cause the infection. It also blocks the production of certain chemical messengers that make the skin red, swollen and itchy.
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Topisone G Cream image
Topisone G Cream image

Product introduction

Topisone G Cream is for external use only. It should be applied as per dose and duration suggested by the doctor. Applying it at the same time every day will help you remember to use it. The affected area should be clean and dry before application of the medicine. You must wash your hands thoroughly before and after applying this medicine. Do not stop using it until you have finished the complete course, even when you feel better. If you stop using this medicine too early, the fungus may continue to grow and the infection may return or worsen.

Some common side effects of this medicine include application site reactions burning, irritation, itching and redness. These are usually mild but let your doctor know if they bother you or last more than a few days. Avoid direct contact with eyes, nose, or mouth. If accidental exposure occurs, rinse immediately with plenty of water.

Uses of Topisone G Cream

Benefits of Topisone G Cream

Skin infections
Topisone G Cream is a combination of medicines used to treat skin infections caused by microorganisms such as bacteria. It works by killing and stopping the growth of infection causing microorganisms, thereby clearing the infection and relieving the symptoms. It also blocks the release of chemicals that cause symptoms such as itching, redness and swelling. Therefore this medicine relieves the inflammation due to these infections.

You should use this medicine for as long as it is prescribed, even if your symptoms disappear, otherwise they may come back. Depending on the type of infection you are treating, this may be several weeks. Even after your skin is completely cured, you may have to apply it occasionally to prevent the symptoms from returning.

Side effects of Topisone G Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Topisone G
  • Application site reactions (burning, irritation, itching and redness)

How to use Topisone G Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Topisone G Cream works

Topisone G Cream is a combination of two medicines: Clobetasone and Gentamicin which treat skin infections. Clobetasone is a steroid medicine. It blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Gentamicin is an antibiotic which kills bacteria by preventing the synthesis of essential proteins required by bacteria to carry out vital functions.

Quick tips

  • You have been prescribed Topisone G Cream for the treatment of skin infections.
  • Wash your skin with a mild cleanser and pat it dry before applying.
  • Apply it as a thin layer onto a clean, dry, unbroken infected area of skin.
  • Do not share your towel or clothes with anyone and wear clean clothes every day to prevent infection.
  • It may take several weeks to show its action. Keep using it as suggested by your doctor.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Topisone G Cream is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Topisone G Cream may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Usually, Topisone G Cream starts working soon after applying it. However, it may take some days to kill all the harmful bacteria and make you feel better.
No, do not stop applying Topisone G Cream and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

Fact Box

Habit Forming

No

Therapeutic Class

DERMA
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No contact delivery
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Fully sanitized facilities
Fully sanitized facilities

User feedback

Once A Day
77%
Twice A Day
15%
Thrice A Day
8%
Bacterial skin infections
67%
Others
33%
Excellent
67%
Average
33%
No Side Effect
100%
With or without food
100%
Average
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Digmedi Pvt Ltd
Address: 501, DKR TOWERS, B-BLOCK,BHAGYANAGAR COLONY, HYDERABAD-500 072 HYDERABAD-500 072 TG 000000 IN , - , .

Vendor Details

Country of origin: India
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