Trental 400 Tablet PR is used to treat peripheral vascular disease (poor circulation to the arms and legs) and intermittent claudication (pain on walking or at rest caused by poor circulation to the legs). It works by increasing the blood flow to the arms and legs.

Trental 400 Tablet PR medicine reduces cramping in the legs that occurs on walking in such patients. It also has beneficial effects in alcohol-related liver damage. Lifestyle modifications like smoking cessation and regular exercise can provide better results with this medicine.

It may cause headache, dizziness, dizziness, sleep disorder, and flushing as side effects. Patients taking this medicine should use caution while driving or operating machines.

Uses of Trental Tablet PR

Peripheral vascular disease
Intermittent claudication

Benefits of Trental Tablet PR

In Peripheral vascular disease

Peripheral vascular disease refers to the condition of disturbed blood circulation in blood vessels. Trental 400 Tablet PR prevents blood from clotting inside the veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). It helps prevent the formation of blood clots and also prevents the existing ones from growing bigger in size. Make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine.

In Intermittent claudication

Intermittent claudication refers to muscle pain on mild exertion (ache, cramp, numbness or sense of fatigue), classically in the calf muscle, which occurs during exercise or even walking, and it gets better with a short period of rest. Trental 400 Tablet PR helps relieve this pain in the legs that is caused due to disturbed blood supply in the legs. It helps prevent formation of blood clots, improves blood flow and maintains free flowing of blood in your body.

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Side effects of Trental Tablet PR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Trental

Bloating
Diarrhea
Flushing (sense of warmth in the face, ears, neck and trunk)
Headache
Heartburn
Lightheadedness
Nausea
Stomach discomfort
Vomiting
Weakness
Dizziness
Sleep disorder

How to use Trental Tablet PR

Use it as advised by your doctor or check the label for directions before use. Trental 400 Tablet PR is to be taken with food.

How Trental Tablet PR works

Trental 400 Tablet PR is a peripheral vasodilator. It works by decreasing the thickness (viscosity) of blood, allowing it to pass more easily through the blood vessels. This effect is beneficial in peripheral vascular disease, where the blood vessels in the arms and legs are narrowed.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Trental 400 Tablet PR. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Trental 400 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Trental 400 Tablet PR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Trental 400 Tablet PR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Trental 400 Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Trental 400 Tablet PR may be needed. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Trental 400 Tablet PR in patients with liver disease. Please consult your doctor.

What if you forget to take Trental Tablet PR?

If you miss a dose of Trental 400 Tablet PR, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

Take it as per dose and duration suggested by your doctor.
Do not drive or perform activities that require mental focus until you know how Trental 400 Tablet PR affects you.
Your doctor may get regular blood tests done to monitor liver function while taking this medicine.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Take it with food, preferably at the same time everyday to avoid missing a dose.

Fact Box

Chemical Class

Methylxanthine Derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Rheologic modifier

Patient concerns

I have been prescribed Trental 400 mg.How long should l take Trental 400 mg under prescription ?

Dr. Vikas Sharma

Neurology

duration depends on the the reason for giving this medicine

Type II diabetic patient having foot pain with blood clotting. The prescribed tab TRENTAL 400 is not available in market. FBS-218, RBS-313

Dr. Sanjay Bhatt

Physician

Trental is available in the market. Try with some other chemist shop. You needs to take diabetic medicine.

Having diabetes ,hypertension amd joint pain since past 5-6 yr by medication diabetes and hyoertension are controlled but peripheral neuropathy of both lower limb also associated with peripheral vascular disease of lower limbs best treatmrnt where and from which departnent??

Dr. Sanjay Bhatt

Physician

A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED. ALWAYS IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you SHOULD not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

During winter, I have acute problem of Blood circulation in leg, as a result, toe gets swellied and finally soars develops. Find, Trental-400Mg is effective for this probelm. But it's not available anywhere, also it's substitutes are also not available. Kindly sugest

Dr. Souvik Sardar

Dermatology

This can be chillblain Use gloves and warm water to reduce these problems Other medicines can be given bt only after checking few parameters Plz visit a nearby dermatologist and also take opinion form a cardiovascular surgeon to rule out any arterial obstruction

Sir, madam I have been suffering from pain in my right ankle accompanied by swelling. I could also feel the pain in my hips as well. I suspect this to be peripheral vascular disease, since i frequently get the cramp whenever I walk or do physical activity in my right ankle.I only feel relieved when I take tablets like Pynor. Please suggest some suggest medication. Thank you.

Dr. Aanchal Maheshwari

Ayurveda

You better consult once with an Ayurvedic physician in person before starting the treatment

User feedback

Patients taking Trental 400 Tablet PR

Twice A Day

80%

Once A Day

20%

What are you using Trental Tablet PR for?

Peripheral va*

58%

Others

21%

Intermittent *

21%

*Peripheral vascular disease, Intermittent claudication

How much was the improvement?

Average

40%

Poor

32%

Excellent

28%

What were the side-effects while using Trental 400 Tablet PR?

No Side Effec*

48%

Nausea

20%

Agitation

Rash

Abdominal dis*

*No Side Effect, Abdominal distension

How do you take Trental Tablet PR?

With food

95%

With or witho*

*With or without food

Please rate Trental 400 Tablet PR on price

Average

46%

Expensive

30%

Not Expensive

24%

Top Cardiologists

Dr. Balbir Singh

MBBS, MD, DM, Fellowship, Fellowship

4.8 ★

Dr. R. R. Kasliwal

MBBS, MD, DM, Fellowship

4.7 ★

Dr. Rajneesh Kapoor

MBBS, MD, DNB

5 ★

Dr. (Col.) Balbir Kalra

MBBS, MD, DM

4.7 ★

Dr. Hemant Gandhi

MBBS, MD, DM

4.8 ★

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 205.
Gersh BJ, Opie LH. Which Therapy for Which Condition? In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 528.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1089-90.
Pentoxifylline. Guildford, Surrey: SANOFI; 2002 [revised 25 May 2016]. [Accessed 25 Jan. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Pentoxifylline. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Pentoxifylline [Patient Information Leaflet]. Ankleshwar: Gujarat: Sanofi India Limited; 2015. [Accessed 06 Apr. 2024] (online) Available from:

Marketer details

Name: Sanofi India Ltd

Address: Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072

Country of origin: India
Expires on or after: April, 2026

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Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Trental 400 Tablet PR

Product introduction

Uses of Trental Tablet PR

Benefits of Trental Tablet PR

In Peripheral vascular disease

In Intermittent claudication

Side effects of Trental Tablet PR

Common side effects of Trental

How to use Trental Tablet PR

How Trental Tablet PR works

Safety advice

What if you forget to take Trental Tablet PR?

All substitutes

Quick tips

Fact Box

Patient concerns

User feedback

Top Cardiologists

Want to share the information?

Disclaimer:

References

Marketer details

In case of any issues, contact us

Lab tests offered by us

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