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Tyvalzi Combipack Injection

rx_imgPrescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Product introduction

Tyvalzi Combipack Injection is a prescription medicine used for the treatment of ischemic stroke. It works by activating specific receptors in the brain that help enhance blood flow and oxygen delivery to the affected brain areas. This helps in healing the brain and speed up recovery.

Tyvalzi Combipack Injection is generally administered as an injection by a doctor or a nurse, typically in a hospital or clinical setting. To ensure the best outcomes from the treatment, follow the doctor’s instructions regarding the dosing schedule. Complete the full course of treatment as prescribed and do not skip any doses.


Tyvalzi Combipack Injection is generally safe and well-tolerated; no common side effects were reported at the recommended dose. However, it may cause some headaches, nausea, dizziness, and fatigue in some people. If these side effects occur, contact your doctor for advice. They may suggest ways to manage these symptoms or adjust the treatment plan.


Before you receive this medicine, let your doctor know if you have a known history of allergy to any medications. Let your doctor also know about any other medications or supplements you are taking if any. Patients should avoid using other medications, particularly anticoagulants and antiplatelet drugs, unless prescribed by the doctor. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss their situation with their doctor, as the safety of Tyvalzi Combipack Injection in these scenarios is not well established.


Uses of Tyvalzi Injection

Benefits of Tyvalzi Injection

In Treatment of Ischemic stroke

In an ischemic stroke, a blood clot blocks blood flow to the brain. Tyvalzi Combipack Injection helps by improving blood flow and oxygen supply to the damaged parts of the brain, which supports the healing process. This can speed up recovery and help the patients regain their brain function more quickly. Tyvalzi Combipack Injection reduces the risk of long-term effects of a stroke and improves the patient's overall quality of life.

Side effects of Tyvalzi Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tyvalzi

  • No common side effects seen

How to use Tyvalzi Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Tyvalzi Injection works

Tyvalzi Combipack Injection works by activating endothelin-B (ETB) receptors in the brain. This stimulates neural progenitor cells (immature brain cells that can grow into new neurons), helping repair brain damage after a stroke. It promotes the growth of new nerve cells and blood vessels (neurovascular remodeling), improves blood flow in the brain, prevents cell death (anti-apoptotic effect), and protects the energy-producing parts of brain cells (mitochondria) while supporting their regeneration.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tyvalzi Combipack Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Tyvalzi Combipack Injection during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Tyvalzi Combipack Injection during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Tyvalzi Combipack Injection may cause side effects which could affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Tyvalzi Combipack Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Tyvalzi Combipack Injection in patients with liver disease. Please consult your doctor.

What if you forget to take Tyvalzi Injection?

If you miss a dose of Tyvalzi Combipack Injection, consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Tyvalzi Combipack Injection is a first-in-class drug to treat acute cerebral ischemic stroke.
  • It can be given up to 24 hours after the onset of symptoms.
  • It should be used only under the supervision of a specialist.

Fact Box

Chemical Class
Peptides
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Selective endothelin-B (ETB) receptor agonist

Patient concerns

On anticogulation(acitrom 1mg)for treatment of ischemic stroke. advised for purtia plus capsules for recovery. Can we take any other brand or company medicine which is compearetively cheaper?
Dr. Vikas Sharma
Neurology
For which of these Medi cine
i am diabetic. my nervous system is week. i am takin ECOSPRIN AV 150/20 Capsules daily one. is it good ?
Dr. Vikas Sharma
Neurology
To prevent stroke , yes

FAQs

What is Tyvalzi Combipack Injection?

Tyvalzi Combipack Injection is a medication used to treat ischemic stroke. It helps improve blood flow and oxygen delivery to the brain, aiding in the recovery and repair of brain cells damaged by the stroke.

How does Tyvalzi Combipack Injection work?

Tyvalzi Combipack Injection works by activating specific receptors in the brain known as endothelin B receptors. This activation helps increase blood flow and oxygen to the affected areas of the brain, promoting healing and recovery.

How is Tyvalzi Combipack Injection administered?

Tyvalzi Combipack Injection is given as an injection by a healthcare professional, usually in a hospital or clinical setting.

Who can take Tyvalzi Combipack Injection?

Tyvalzi Combipack Injection is prescribed for patients who have experienced an ischemic stroke. Your doctor will determine if it is the right treatment for you based on your medical condition and history.

How can I maximize the benefits of Tyvalzi Combipack Injection?

Follow your doctor’s instructions carefully. Attend all scheduled appointments, complete the full course of treatment, and inform your doctor about any other medications or supplements you are taking.

Can I take other medications while on Tyvalzi Combipack Injection?

You should inform your doctor about all other medications or supplements you are taking. Some drugs, especially blood thinners, may interact with Tyvalzi Combipack Injection.

Is Tyvalzi Combipack Injection safe during pregnancy or breastfeeding?

The safety of Tyvalzi Combipack Injection during pregnancy or breastfeeding is not well established. If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your doctor before starting treatment.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Keam SJ. Sovateltide: First Approval. Drugs. 2023;83(13):1239-1244. [Accessed 27 June 2024] (online) Available from: External Link
  2. Gulati A, Agrawal N, Vibha D, et al. Safety and Efficacy of Sovateltide (IRL-1620) in a Multicenter Randomized Controlled Clinical Trial in Patients with Acute Cerebral Ischemic Stroke. CNS Drugs. 2021;35(1):85-104. [Accessed 27 June 2024] (online) Available from: External Link
  3. Anil G, Sikandar A, Pamidimukkala V, et al. Sovateltide (Tycamzzi) in patients with cerebral ischemic stroke. A randomized multicenter study. Critical Care Medicine. 2023;51(1):252. [Accessed 27 June 2024] (online) Available from: External Link
  4. Press Release: Sun Pharma and Pharmazz Inc. enter into licensing agreement for introducing Tyvalzi™ (Sovateltide) in India. [Accessed 27 June 2024] (online) Available from: External Link

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135
Country of origin: India

1236
Inclusive of all taxes
MRP1339.69  8% OFF
1.0 Injection in 1 box
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