Vertex 5mg Tablet is used in the treatment of vertigo (dizziness) due to ear problems (Meniere’s syndrome and other labyrinthine disorders), nausea, vomiting, and migraine caused by various conditions. Additionally, can be used as a short-term treatment for non-psychotic anxiety.

Vertex 5mg Tablet is taken after meals in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should take this medicine until your doctor tells you to stop. This medicine is not recommended for long term treatment.

The most common side effect is sedation or drowsiness, therefore, it is not advisable to drive or and operate machineries. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. It can also cause orthostatic hypotension (sudden lowering of blood pressure on standing) and blurred vision. This is temporary and usually resolves with time. Contact your doctor straight away if you are at all concerned about these side effects.

Before taking this medicine you should let your doctor know if you have jaundice (yellowing of the skin or eyes), epilepsy, muscle weakness (myasthenia gravis), and increased pressure in the eye (glaucoma). Inform your doctor if you have liver, kidney, and heart problems. Let your doctor also know about all other medications you are taking as some may affect, or be affected by this medicine. Pregnant or breastfeeding women should consult their doctor.

Uses of Vertex Tablet

Benefits of Vertex Tablet

In Treatment of Migraine

Vertex 5mg Tablet helps treat and prevent migraine headaches. It changes the electrical activity in the brain, blocks chemicals responsible for pain sensation and also blocks signals that cause nausea/vomiting associated with migraines. By preventing and reducing the frequency of migraine headaches, it can help you carry out your daily activities and have a better quality of life.

In Treatment of Short term anxiety

Vertex 5mg Tablet reduces the symptoms of excessive anxiety and worry that are triggered only at the time of stressful conditions that last for a shorter duration. These could be job interviews, exams, stage performances, etc. It can effectively manage feelings of restlessness, tiredness, difficulty concentrating, and feeling irritable.

In Treatment of Vertigo

Vertigo means a spinning sensation or dizziness that is triggered due to frequent movement or in people suffering from Meniere’s disease. It usually happens due to problem in the ear (vestibular). Vertex 5mg Tablet helps treat this sensation effectively. If you feel dizzy while getting up from the bed, sit for a while and then rise slowly to avoid having an accidental fall. It acts on the vestibular system and suppresses the spinning sensation.

In Treatment of Nausea

Vertex 5mg Tablet is often used to prevent nausea and vomiting that may be caused as a side effect of some other medicine and in post-operative patients suffering from nausea/vomiting (in adults only). It acts on the receptors responsible for causing nausea and vomiting by blocking them.

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Side effects of Vertex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Vertex

Drowsiness
Orthostatic hypotension (sudden lowering of blood pressure on standing)

How to use Vertex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Vertex 5mg Tablet is to be taken with food.

How Vertex Tablet works

Vertex 5mg Tablet is a vestibular suppressant, i.e., it suppresses the vestibular apparatus in the inner ear by blocking the H1 receptor and stops vertigo. It acts within 30 minutes and, therefore, is effective during acute attacks. It also acts as a dopamine antagonist. Dopamine controls the region in the brain that causes nausea and vomiting, and this medicine blocks the action of dopamine. Therefore, Vertex 5mg Tablet shows an anti-nauseating and antiemetic action. The mechanism of action by which prochlorperazine relieve headache and anxiety is probably related to it being serotonin (5HT3) receptor antagonist and dopamine (D2) receptor antagonist.

Safety advice

Alcohol

UNSAFE

Vertex 5mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Vertex 5mg Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CAUTION

Vertex 5mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
However, occasional short-term use of Vertex 5mg Tablet for the treatment of nausea and vomiting poses little risk to the breastfed infant.

Driving

UNSAFE

Vertex 5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Vertex 5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Vertex 5mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Vertex 5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Vertex 5mg Tablet may be needed. Please consult your doctor.

What if you forget to take Vertex Tablet?

If you miss a dose of Vertex 5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Vertex 5mg Tablet

₹1.35/Tablet

Acuvert 5mg Tablet MD

Abbott

₹7.73/tablet

473% costlier

Systel 5mg Tablet

Marsha Pharma Pvt Ltd

₹6.5/tablet

381% costlier

Acuvert Tablet

Abbott

₹8.09/tablet

499% costlier

Stemil 5mg Tablet

Theo Pharma Pvt Ltd

₹2.77/tablet

105% costlier

Prometil 5mg Tablet

Rhombus Pharma Pvt Ltd

₹2.48/tablet

84% costlier

View all substitutes

Quick tips

Vertex 5mg Tablet is used for the prevention and treatment of nausea and vomiting.
It may also be used to treat dizziness associated with problems of the inner ear such as Meniere’s Syndrome.
It may cause sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Avoid consuming alcohol when taking the Vertex 5mg Tablet as it may cause excessive drowsiness.
It makes you more likely to get heatstroke. Avoid heavy exercising and drink plenty of fluids.
It can cause your skin to be more sensitive to sunlight. Avoid exposure to direct sunlight while having this medicine.

Fact Box

Chemical Class

Phenothiazines Derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Dopamine (D2) receptor antagonist- Prochlorperazine

Interaction with drugs

Taking Vertex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Iopamidol (Oral Route) Life-threatening

Concurrent use may increase the risk of seizures. Do not consume Prochlorperazine 48 hours before and At least 12 hours after consuming Iopamidol.

Iohexol (Oral Route) Life-threatening

Concurrent use may increase the risk of seizures. Do not consume Prochlorperazine 48 hours before and At least 24 hours after consuming Iohexol.

Moxifloxacin (Oral Route) Severe

Concomitant use may affect heart rhythm. Do not consume Moxifloxacin with Prochlorperazine. If concurrent use is essential, watch out for symptoms such as muscle spasms, tremors, ... More

Lithium carbonate (Oral Route) Severe

Prochlorperazine may increase the rate of release of Lithium carbonate in the blood. If concurrent use is essential, watch out for symptoms such as double vision, weakness, dizzin... More

Moxifloxacin (Oral Route) Severe

Concomitant use may affect heart rhythm. Do not consume Moxifloxacin with Prochlorperazine. If concurrent use is essential, watch out for symptoms such as muscle spasms, tremors, ... More

View all drug interactions

Patient concerns

vertex baldness, scalp itching

Dr. Saurav Arora

Homeopathy

Please send pictures of your scalp

vertex baldness, scalp itching

Dr. Saurav Arora

Homeopathy

Please send picture of your scalp

From last week I m having problem of vertigo, nausea. All reports are ok. Doctor says it's survical problem but my bp is also getting low and high. One day low and one day high in office also very much tension is there. So don't know what is the reason.kindly guide as dizziness is not getting resolved after a week 's medication. Please guide

Dr. Anuneet Sabharwal

Psychiatry

Your stress is causing it. You may need short term medication

User feedback

What are you using Vertex Tablet for?

Others

50%

Vertigo

25%

Vomiting

25%

How much was the improvement?

Average

100%

What were the side-effects while using Vertex 5mg Tablet?

No Side Effec*

100%

*No Side Effect

How do you take Vertex Tablet?

With food

100%

Please rate Vertex 5mg Tablet on price

Expensive

67%

Average

33%

FAQs

How does Vertex 5mg Tablet work?

Vertex 5mg Tablet is used to treat mental disorders like schizophrenia. It is also used to treat and prevent nausea, and vomiting.It may be used to treat anxiety (short-term) in certain cases where other anti-anxiety drugs have been ineffective. It is also used to treat nausea, vomiting, dizziness or spinning sensations (vertigo) due to Meniere's disease.It belongs to a class of medication call phenothiazines. It acts on the central nervous system by blocking certain receptors thus producing an anti-psychotic and anti-vomiting effect

Does Vertex 5mg Tablet expire?

Yes, Vertex 5mg Tablet does expire. Please check the expiry date written on the pack and it refers to the last day of that month. Do not use Vertex 5mg Tablet after the expiry date.

Is Vertex 5mg Tablet available over the counter?

Vertex 5mg Tablet is not available over the counter. It is available only on prescription from the doctor

Is Vertex 5mg Tablet safe to use?

Vertex 5mg Tablet is safe to use for a prescribed duration in the dose as advised by a doctor.

How long can I take Vertex 5mg Tablet for?

Vertex 5mg Tablet should only be taken for the duration as advised by the doctor for your condition.

Is Vertex 5mg Tablet addictive?

Vertex 5mg Tablet is not known to have any addictive potential. Please consult your doctor in case you have any other query regarding the same.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Prochlorperazine. Skipton, United Kingdom: Dales Pharmaceuticals Limited; 2016. [Accessed 28 Mar. 2019] (online) Available form:
Drugs.com. Prochlorperazine Pregnancy and Breastfeeding Warnings. [Accessed 28 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Prochlorperazine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
Prochlorperazine [Prescribing Information]. Research Triangle Park, NC: GlaxoSmithKline; 2004. [Accessed 20 Feb. 2024] (online) Available from:

Marketer details

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Address: geeta vihar, threekay lane, ferozepur road near geeta mandir, ludhiana-142028, punjab, india

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.