Xtrant 140mg Capsule
Prescription Required
Product introduction
Xtrant 140mg Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.
Xtrant 140mg Capsule should be taken on an empty stomach. The calcium in the stomach might affect the working of drug, so better to avoid milk, dairy products such as cheese and avoid taking it in combination with an antacid or other medicine containing calcium, magnesium or aluminum. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, anemia (low number of red blood cells), increased liver enzymes and fluid retention. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Regular blood tests are required to check your blood, liver function and the level of calcium in your blood.
Before taking it, tell your doctor if have heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Xtrant 140mg Capsule should be taken on an empty stomach. The calcium in the stomach might affect the working of drug, so better to avoid milk, dairy products such as cheese and avoid taking it in combination with an antacid or other medicine containing calcium, magnesium or aluminum. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, anemia (low number of red blood cells), increased liver enzymes and fluid retention. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Regular blood tests are required to check your blood, liver function and the level of calcium in your blood.
Before taking it, tell your doctor if have heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Xtrant Capsule
Benefits of Xtrant Capsule
In Prostate cancer
Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Xtrant 140mg Capsule decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.
Side effects of Xtrant Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Xtrant
- Nausea
- Vomiting
- Anemia (low number of red blood cells)
- Increased liver enzymes
- Decreased white blood cell count
- Diarrhea
- Breast enlargement in male
How to use Xtrant Capsule
Take this medicine in the dose and duration as advised by your doctor. Xtrant 140mg Capsule may be taken with or without food, but it is better to take it at a fixed time.
Avoid Xtrant 140mg Capsule with dairy products such as milk, cheese, curd, butter, paneer and ice cream.
Avoid Xtrant 140mg Capsule with dairy products such as milk, cheese, curd, butter, paneer and ice cream.
How Xtrant Capsule works
Estramustine belongs to a class of anticancer/cytotoxic drugs called antimicrotubule agents. It works by interfering with production of certain proteins which are necessary for tumor cell growth and reproduction. It also increases the estrogen levels, which in turn interferes with prostate cancer by slowing/stopping the growth of cancer cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Xtrant 140mg Capsule. Please consult your doctor.
Pregnancy
UNSAFE
Xtrant 140mg Capsule is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Xtrant 140mg Capsule during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Xtrant 140mg Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Xtrant 140mg Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Xtrant 140mg Capsule may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Xtrant 140mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Xtrant 140mg Capsule may be needed. Please consult your doctor.
Use of Xtrant 140mg Capsule is not recommended in patients with the severe liver disease.
Use of Xtrant 140mg Capsule is not recommended in patients with the severe liver disease.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Xtrant 140mg Capsule
₹75.36/Capsule
Estramin 140mg Capsule
Samarth Life Sciences Pvt Ltd
₹125.3/capsule
66% costlier
X TRANT 140 MG CAPSULE
Natco Pharma Ltd
₹142.03/capsule
88% costlier
Estram 140mg Capsule
United Biotech Pvt Ltd
₹154.6/capsule
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Quick tips
- Xtrant 140mg Capsule should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal.
- Avoid taking antacids, calcium or magnesium, milk products and multivitamins, as these may interfere with the effect of the medicine.
- Your doctor may get regular blood tests done to monitor your calcium level, liver function, blood cell count in your blood.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- Do not stop taking medicine without talking to your doctor first.
Fact Box
Chemical Class
Estradiol, and Nitrogen Mustard Compounds
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Anticancer-others
Interaction with drugs
Taking Xtrant with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use must be avoided. Please consult with your doctor regarding appropriate interval between Estramustine and Purified Vi Polysaccharide Typhoid Vaccine.
Concurrent use
Concurrent use must be avoided. Please consult with your doctor regarding appropriate interval between Estramustine and Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).
Concurrent use must be avoided. Please consult with your doctor regarding appropriate interval between Estramustine and Cholera Vaccine (Inactivated).
Concurrent use may lead to s
Avoid taking Pegfilgrastim within the 24-hour period prior to and 24 hours after Estramustine. Please consult with your doctor regardine appropriate time interval. Estramustine may
Do not consume Tamoxifen with Estramustine if you have or had breast cancer. If essential, consult your doctor. Estramustine may reduce the efficacy of Tamoxifen.
Patient concerns
FAQs
What is Xtrant 140mg Capsule phosphate?
Xtrant 140mg Capsule belongs to a class of anticancer/cytotoxic drugs called antimicrotubule agents used in the treatment of prostate cancer.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1709.
- Estramustine sodium phosphate. Sandwich, Kent: Pfizer Limited; 2002 [revised Feb. 2019]. [Accessed 20 Feb. 2019] (online) Available from:
- Drugs.com. Estramustine Pregnancy and Breastfeeding Warnings. [Accessed 27 Mar 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Marketer details
Name: Natco Pharma Ltd
Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Country of origin: India
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₹7536
Inclusive of all taxes
MRP₹7773 3% OFF
100.0 capsules in 1 bottle
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