Yervoi 50mg Injection

Ipilimumab (50mg)

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Yervoi 50mg Injection is a medicine used to treat a kind of skin cancer called melanoma. It is used when the melanoma has spread or cannot be removed by surgery. Yervoi 50mg Injection boosts the immune system to attack cancer cells more effectively and kills them. It also prevents the growth and further spread of the cancer cells.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 02 Jan 2026 | 10:17 PM (IST)

₹209969

₹228500

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1 Injection

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Gurgaon

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General Information

Contains

Ipilimumab (50mg)

Marketer

Bristol Myers Squibb

The content is shown in English

Product introduction

Yervoi 50mg Injection is generally given under the supervision of a docotr or a nurse. Do not self-administer this medicine at home. Taking it in the wrong way or taking too much can cause very serious side effects. It is injected into your vein through an intravenous (IV) line. Your doctor will decide the dose and duration of the treatment. Get the injection for as long as the doctor prescribes it. Your doctor may also do blood tests before starting and during treatment with this medicine.

The most common side effects of this medicine include feeling tired, diarrhea, nausea, itching, rash, vomiting, and headache. Inform your doctor if any of these side effects persist or bother you. Your doctor may suggest ways to prevent the side effects. Tell your doctor right away if you get symptoms, such as chills, itching or rash, flushing, shortness of breath, dizziness, or feel like passing out, during the infusion.

Before you receive Yervoi 50mg Injection, tell your doctor if you have immune system problems, have had an organ transplant, or have liver problems. Let your doctor also know about all the medicines you take, including all prescription and over-thecounter medicines, vitamins, and herbal supplements. Pregnant and nursing mothers should not take this medicine as it may harm the developing baby. Women who are planning for pregnancy should use effective birth control during treatment with this medicine and for 3 months after the last dose.

Uses of Yervoi Injection

Treatment of Melanoma

Benefits of Yervoi Injection

Treatment of Melanoma
Melanoma is a type of skin cancer that develops in melanocytes, the cells that produce the pigment called melanin. Melanin is the pigment that gives the skin its color. Melanoma is the most deadly and aggressive kind of skin cancer. Yervoi 50mg Injection boosts the immune system to attack cancer cells more effectively and kills them. It also prevents the growth and further spread of the cancer cells. This can lead to better control of the disease and longer survival in some patients.

Side effects of Yervoi Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Yervoi

Dermatitis
Eczema
Swelling of lymph nodes
Oropharyngeal pain
Nasopharyngitis (inflammation of the throat and nasal passages)
Upper respiratory tract infection
Rash
Flu
Bronchitis (inflammation of the airways)

How to use Yervoi Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Yervoi Injection works

Yervoi 50mg Injection activates the immune system against cancer cells by allowing certain white blood cells to multiply and increase the body's immune response.

Quick tips

Make sure you receive Yervoi 50mg Injection only in a medical setting under your doctor’s supervision, as it needs close monitoring during and after administration.
Tell your doctor about any signs of fever, diarrhea, skin rash, or eye problems, even if mild. These could be early signs of serious immune-related side effects.
Avoid starting any new medicines, including over-the-counter drugs or supplements, without telling your doctor, as they might interfere with your treatment.
Stay well-hydrated before and after Yervoi 50mg Injection, unless told otherwise, to support kidney function and reduce the chance of side effects.
When traveling or consulting another doctor, always carry your treatment history or medical card to inform them you are on Yervoi 50mg Injection (an immune-based medicine). This ensures safe and coordinated care.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Yervoi 50mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Yervoi 50mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Yervoi 50mg Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Yervoi 50mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

SAFE IF PRESCRIBED

Yervoi 50mg Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

SAFE IF PRESCRIBED

Yervoi 50mg Injection is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Yervoi with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Do not use Ipilimumab with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not use Ipilimumab with Cholera Vaccine (Inactivated).

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Do not use Ipilimumab with Purified Vi Polysaccharide Typhoid Vaccine.

Moderate

Abciximab (Injection Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.

Moderate

Acenocoumarol (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.

Frequently asked questions

What is Yervoi 50mg Injection used for?

Yervoi 50mg Injection is a type of immunotherapy used to treat advanced melanoma (skin cancer) and certain types of kidney cancer. It works by helping the immune system fight and destroy cancer cells more effectively.

How does Yervoi 50mg Injection work in treating cancer?

Yervoi 50mg Injection is a CTLA-4 checkpoint inhibitor, which means it helps activate your immune system's T-cells to recognize and attack cancer cells. It removes the brakes from immune responses, making it a powerful immune-based cancer treatment.

Can Yervoi 50mg Injection cause serious or life-threatening side effects?

Yes, Yervoi 50mg Injection can cause severe immune-related side effects in organs such as the colon (colitis), liver (hepatitis), lungs (pneumonitis), skin (rashes, blisters), thyroid (endocrine issues), and kidneys (nephritis). Early detection and treatment are important. Always report new or unusual symptoms promptly to your doctor.

What precautions should I take before starting Yervoi 50mg Injection therapy?

Before taking Yervoi 50mg Injection, you should inform your doctor if you have a history of autoimmune diseases, are on immunosuppressants, have organ transplants, or are pregnant or breastfeeding. You may need additional monitoring if you have pre-existing liver, lung, or kidney conditions.

What should I do if I experience diarrhea or stomach pain while on Yervoi 50mg Injection?

Diarrhea or stomach pain could be signs of immune-related colitis, a serious side effect of Yervoi 50mg Injection. Do not self-treat with over-the-counter medication if you experience these symptoms. Contact your oncologist immediately, as you may need specific medicine or a temporary pause in treatment.

Are there any contraindications to receiving Yervoi 50mg Injection?

While there is no absolute contraindication mentioned in the product label, Yervoi 50mg Injection should be used with extreme caution in patients with autoimmune conditions or those who have had organ transplants, due to the risk of serious immune complications.

What kind of monitoring will I need during Yervoi 50mg Injection treatment?

During Yervoi 50mg Injection treatment, your doctor will monitor you for immune-related side effects using regular blood tests to check liver, kidney, and thyroid function. You will also be watched by your doctor for symptoms like cough, diarrhea, rashes, or vision changes to catch any early signs of toxicity.

How long does it take for Yervoi 50mg Injection to work?

The time Yervoi 50mg Injection takes to see results varies from person to person. Some patients may notice improvement within a few weeks, while others may take longer. Your doctor will monitor your progress through regular check-ups and scans.

What should I avoid while receiving Yervoi 50mg Injection?

Your doctor may suggest that you avoid activities that require alertness until you know how the treatment affects you, limit exposure to sunlight, as Yervoi 50mg Injection may make your skin more sensitive to UV rays, avoid live vaccines (e.g., measles, flu nasal spray) during treatment, as your immune system may not respond properly, etc.

Can Yervoi 50mg Injection cure my cancer?

Yervoi 50mg Injection is not a cure for cancer, but it can help control the growth and spread of advanced melanoma and certain kidney cancers. It may improve symptoms and prolong survival in some patients.

Fact Box

Chemical Class

Peptides

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Monoclonal Antibodies (mAbs)

References

Ipilimumab [Prescribing Information]. Princeton, NJ: Bristol-Myers Squibb Company; 2025. [Accessed 02 Jan. 2026]. Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Bristol Myers Squibb
Address: Bristol Myers Squibb Corporate Headquarters 430 E. 29th Street, 14th Floor, New York, NY 10016

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Yervoi 50mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Yervoi 50mg Injection

Payment

Return

Expiry after

Save more with additional offers

General Information

Contains

Marketer

Product introduction

Uses of Yervoi Injection

Benefits of Yervoi Injection

Side effects of Yervoi Injection

How to use Yervoi Injection

How Yervoi Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Cholera Vaccine (Inactivated) (Oral Route)

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Abciximab (Injection Route)

Acenocoumarol (Oral Route)

Frequently asked questions

What is Yervoi 50mg Injection used for?

How does Yervoi 50mg Injection work in treating cancer?

Can Yervoi 50mg Injection cause serious or life-threatening side effects?

What precautions should I take before starting Yervoi 50mg Injection therapy?

What should I do if I experience diarrhea or stomach pain while on Yervoi 50mg Injection?

Are there any contraindications to receiving Yervoi 50mg Injection?

What kind of monitoring will I need during Yervoi 50mg Injection treatment?

How long does it take for Yervoi 50mg Injection to work?

What should I avoid while receiving Yervoi 50mg Injection?

Can Yervoi 50mg Injection cure my cancer?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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