Yes, Ambrisentan commonly causes an increase in liver enzymes. It may rarely cause liver injury and inflammation of the liver because of the body’s own defences (autoimmune hepatitis). Consult your doctor if you have nausea, vomiting, loss of appetite, dark-colored urine and yellowing of the skin.

Usually, the doctors advise to take one dose of Ambrisentan. You can take it with or without food but prefer taking it at the same time each day. Swallow it whole with a glass of water. Do not crush, chew or break it into pieces.

No, you should not stop taking Ambrisentan without consulting your doctor as this may worsen your condition. Talk to your doctor if you need to stop it.

Ambrisentan may cause serious birth defects if taken during pregnancy. Therefore, every woman who is capable of becoming pregnant should get a pregnancy test done before starting Ambrisentan. Additionally, during treatment with Ambrisentan you should use two reliable methods of contraception to ensure that you do not get pregnant.

The serious side effects of Ambrisentan are swelling all over the body (fluid retention), decreased sperm count and low red blood cell count (anemia). Tell your doctor if you have any unusual weight gain, tiredness, or trouble breathing.

Ambrisentan is used to treat pulmonary hypertension in adults. Pulmonary hypertension is a condition wherein there is increased blood pressure in the pulmonary arteries (blood vessels that carry blood from heart to lungs). Ambrisentan lowers the blood pressure by relaxing the pulmonary arteries, making it easier for the heart to pump blood through them.

Taking more than the recommended dose of Ambrisentan may cause headache, flushing, dizziness, or nausea. It may cause low blood pressure which may further lead to lightheadedness. Contact your doctor immediately or seek emergency medical services in a nearby hospital if you take more than the recommended doses of this medicine.