Bempedoic acid

Information about Bempedoic acid

Bempedoic acid Uses

Bempedoic acid is used in the treatment of high cholesterol.

How Bempedoic acid works

Bempedoic acid works by blocking an enzyme (adenosine triphosphate-citrate lyase) that is required to make “bad” cholesterol (low-density lipoprotein) in the liver, which results in lower levels of "bad" cholesterol.

Common side effects of Bempedoic acid

Pain in extremities, Anemia (low number of red blood cells), Increased liver enzymes, Upper respiratory tract infection, Muscle spasm, Increased uric acid level in blood, Back pain, Abdominal pain, Bronchitis (inflammation of the airways)
CONTENT DETAILS
Written By
Dr. Lipika Khurana
PGDHHM, BDS
Written By
Dr. Betina Chandolia
MDS, BDS
Reviewed By
Dr. Lalit Kanodia
MBA, MD Pharmacology
Written By
Dr. Anuj Saini
MMST, MBBS
Reviewed By
Dr. Varun Gupta
MD Pharmacology, MBBS
Written By
Dr. Betina Chandolia
MDS, BDS
Reviewed By
Dr. Ashish Ranjan
MD (Pharmacology), MBBS
Reviewed By
Dr. Rajeev Sharma
MBA, MBBS
Last updated
08 Nov 2024 | 06:31 AM (UTC)

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Expert advice for Bempedoic acid

  • Take Bempedoic acid after a meal or with a snack to avoid gastrointestinal problems.
  • Inform your doctor if you experience fatigue, muscle weakness, or muscle or joint pain.
  • Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform them if you notice signs of liver problems, such as stomach pain, unusually dark urine, yellowing skin, or eyes.
  • Lifestyle changes, like a low-fat and salt diet, exercise, not smoking, and cutting down on the amount of alcohol you normally drink, may help this medication work better.
  • Take it as per dose and duration suggested by the doctor.
  • Take it with or without food. 
  • Your doctor may get regular blood tests done to monitor lipid levels, kidney function, and lung function while you are taking this medicine.
  • Inform your doctor if you notice muscle pain or muscle weakness while you are taking this medicine.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 
  • Do not stop taking Bempedoic acid suddenly without talking to your doctor.

Frequently asked questions for Bempedoic acid

Bempedoic acid

Q. How long does it take for Bempedoic acid to work?

In one of the studies, Bempedoic acid has been shown to reduce cholesterol levels by 17-28% after 12 weeks.

Q. Does Bempedoic acid make you tired?

Tiredness and fatigue are some of the side effects of this medicine. If you feel tired along with chest pain, or rapid heartbeat, call your doctor immediately, as these could be signs of an emergency.

Q. Does Bempedoic acid affect the liver?

Bempedoic acid can affect your liver, but rarely cause liver damage. In some people, this medicine may increase levels of liver enzymes which usually resolve or improve with continued therapy or after the discontinuation of the therapy.

Q. In what cases the doctor won't prescribe Bempedoic acid?

Your doctor won't prescribe this medicine if you have had a tendon rupture in the past. This is because tendon rupture is a possible side effect of the drug. Tendon rupture is damage to the tendons which are tissues that connect muscles to bones. Symptoms of tendon rupture may include pain, swelling, tears, and inflammation of tendons including the arm, shoulder, and back of the ankle. You have a higher risk of tendon rupture if you are 60 years or older or have kidney failure.

Q. How should I take Bempedoic acid?

One tablet of Bempedoic acid is to be taken once daily with or without food for as long as it is prescribed by the doctor. However, it is advisable to always follow your doctor's instructions in taking this medicine.

Q. What is LDL or bad cholesterol?

LDL or low-density lipoprotein is called bad cholesterol because it causes a buildup of cholesterol in the blood. This leads to blockage in the heart and is a direct cause of heart attacks, strokes, and peripheral artery disease.

Q. What is HDL or good cholesterol?

HDL or high-density lipoprotein is also called good cholesterol because it carries cholesterol from your blood to your liver to be removed. This reduces the risk of heart disease.

Q. How can I check my cholesterol level?

You can book a lipid profile test with any accredited laboratory. This test helps you monitor your total cholesterol, LDL levels, HDL levels, triglycerides, and the ratio between cholesterol and HDL. You may need to fast for a period of 10-12 hours before giving your blood sample for this test. After receiving your test report, consult a doctor to help you evaluate the test results.

Q. What is the normal cholesterol level in a blood test?

Your total cholesterol level should be 125 to 200 mg/dL, LDL should be less than 100 mg/dL, and HDL should be 40 mg/dL or higher.

Q. What will happen if I have high cholesterol?

If you have a high cholesterol level, it builds up on the walls of your arteries. This condition causes arteries to become narrow, and the narrowed blood vessels reduce blood flow to the heart. This can lead to a heart attack or stroke.

Q. What lifestyle changes can help improve the effectiveness of this medicine?

Along with taking Bempedoic acid, taking a low-fat diet, exercising regularly, reducing body weight, and limiting alcohol consumption can help improve the effectiveness of this medicine and lower cholesterol levels.

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