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Chloramphenicol + Prednisolone

Written By Dr. Anuj SainiReviewed By Dr. Rajeev Sharma
Last updated 03 Nov 2025 | 11:11 AM (UTC)

Chloramphenicol + Prednisolone Uses

Chloramphenicol+Prednisolone is used in the treatment of ear infection.

How Chloramphenicol + Prednisolone works

Chloramphenicol + Prednisolone is a combination of two medicines: Chloramphenicol and Prednisolone. Chloramphenicol is an antibiotic which stops bacterial growth by inhibiting synthesis of essential proteins required by bacteria to carry out vital functions. Prednisolone is a steroid medicine. It blocks the production of certain chemical messengers (prostaglandins) that cause redness, swelling and itching after an allergy or infection.

Common side effects of Chloramphenicol + Prednisolone

Ear discomfort, Itching, Pain
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Expert advice for Chloramphenicol + Prednisolone

  • Chloramphenicol + Prednisolone must be used as per dose and duration suggested by the doctor.
  • Do not touch the tip to any surface, or to your ear, to avoid contamination.
  • Talk to your doctor if your symptoms haven't started to improve within two days of starting treatment, if they get worse during treatment or if you get another ear infection.
  • Avoid contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get the drop in these areas.
  • Stop using the medicine and inform your doctor if you notice ear irritation, burning sensation or allergic reaction. 

Frequently asked questions for Chloramphenicol + Prednisolone

Usually, Chloramphenicol+Prednisolone starts working soon after using it. However, it may take some days to kill all the harmful bacteria and make you feel better.
No, do not stop using Chloramphenicol+Prednisolone and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.