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Epalrestat + Methylcobalamin + Pregabalin

Written By Dr. Anuj SainiReviewed By Dr. Rajeev Sharma
Last updated 03 Apr 2024 | 04:44 PM (UTC)

Epalrestat + Methylcobalamin + Pregabalin Uses

Epalrestat+Methylcobalamin+Pregabalin is used in the treatment of diabetic nerve pain.

How Epalrestat + Methylcobalamin + Pregabalin works

Epalrestat + Methylcobalamin + Pregabalin is a combination of three medicines: Epalrestat , Methylcobalamin and Pregabalin which treat diabetic nerve disease. Epalrestat an aldose reductase inhibitor. It blocks the accumulation of sorbitol in cells, which causes diabetic nerve disease. Methylcobalamin is a form of vitamin B which help in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells.

Common side effects of Epalrestat + Methylcobalamin + Pregabalin

Nausea, Vomiting, Drowsiness, Dizziness, Tiredness, Uncoordinated body movements, Increased liver enzymes
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Expert advice for Epalrestat + Methylcobalamin + Pregabalin

  • Take it only as per the dose and duration prescribed by your doctor. 
  • Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
  • Inform your doctor if you have:
    • Cut or sore on your feet that is infectious or not healing
    • Burning or tingling sensation in arm or feet that hamper your routine activities
    • Trouble in digestion, urination, or sexual functioning
    • Dizziness
  • To prevent diabetic nerve pain, wear proper footwear and examine your feet every day to detect lesions early.
  • Monitor your blood sugar level regularly.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.