Neostigmine

Information about Neostigmine

Neostigmine Uses

Neostigmine is used in the treatment of myasthenia gravis, paralytic ileus, post-operative urinary retention and reversal of effect of skeletal muscle relaxant after surgery.

How Neostigmine works

Neostigmine is a reversible cholinesterase inhibitor. It increases the level of acetylcholine, a chemical messenger in the brain, by suppressing acetylcholinesterase (enzyme). This acetylcholine further triggers muscle contracting receptors which helps in muscle contraction.

Common side effects of Neostigmine

Nausea, Vomiting, Diarrhea, Excessive salivation, Increased sweating, Stomach cramp
CONTENT DETAILS
Written By
Dr. Swati Mishra
BDS
Reviewed By
Dr. Khushbu Goel
DM, MD
Last updated
11 Jun 2020 | 03:59 PM (UTC)

We provide you with authentic, trustworthy and revelant information

Want to know more

Available Medicine for Neostigmine

TilstigminTablets India Limited
₹511 variant(s)
MyostigminNeon Laboratories Ltd
₹4 to ₹473 variant(s)
NeotagminThemis Medicare Ltd
₹5 to ₹212 variant(s)
BeemineBiomiicron Pharmaceuticals
₹211 variant(s)
NestigSPM Drugs Pvt Ltd
₹171 variant(s)
NeomineZydus Cadila
₹211 variant(s)
StigmeraseMiracalus Pharma Pvt Ltd
₹231 variant(s)
TilistigminTablets India Limited
₹491 variant(s)
NeofavFavnox Pharmaceuticals Private Limited
₹271 variant(s)
MyostigArco Lifesciences
₹201 variant(s)

Expert advice for Neostigmine

  • Take it with food to avoid an upset stomach.
  • Take it as per the dose and duration advised by your doctor. Overdosing can result in extreme muscle weakness.
  • It may cause dizziness or blurred vision. Do not drive or do anything requiring concentration until you know how it affects you.
  • Do not drink alcohol while taking this medicine as it may worsen the side effects.
  • Inform your doctor if you have an existing kidney problem, parkinson's disease, asthma, or stomach disorders.

Frequently asked questions for Neostigmine

Neostigmine

Q. Does Neostigmine treat myasthenia gravis? How long do I need to take it?

Neostigmine relieves the symptoms of myasthenia gravis but does not cure it. It does so by reducing and improving muscle weakness. The length of time for which you need to take Neostigmine will depend on your condition. Do not stop taking Neostigmine until and unless advised by your doctor, even if you start feeling better.

Q. How long does Neostigmine take to start working?

Neostigmine takes about 5 to 15 minutes to start working and remains effective for 2-4 hours.

Q. Is Neostigmine a steroid?

No, Neostigmine is not a steroid. It belongs to cholinesterase inhibitor group of medicines. Neostigmine work by preventing the breakdown of a chemical called acetylcholine.

Q. Does it cause weight gain?

No, Neostigmine does not cause weight gain. Your weight gain may be due to inactivity related to muscle weakness in myasthenia gravis.

Q. Is Neostigmine safe to use?

Yes, Neostigmine is safe if used in the dose and duration prescribed by the doctor.

Q. I felt better when I started taking Neostigmine but I have noticed recently that I get tired easily and quickly. Will increasing the dose help me?

If your symptoms have started reappearing, then it could be due to increased severity of myasthenia gravis or excess dose of Neostigmine. Both the conditions have similar effects, so it becomes very difficult to differentiate between the two. Do not increase the dose on your own and consult your doctor immediately.

Q. Can I take Neostigmine for constipation?

No, Neostigmine should not be taken for any type of constipation. However, its use is limited to cases of constipation caused by paralysis of intestine and strictly on prescription by the doctor.

Q. What should I do if I accidentally take more than the dose required?

You should seek immediate medical help in case of overdose of Neostigmine.Excess of Neostigmine may cause stomach pain, nausea, vomiting, diarrhea, blurred vision, difficulty in breathing, and excessive sweating, salivation, and weakness. It can even lead to paralysis.

Q. Does Neostigmine have any abuse potential?

No, there is no evidence of Neostigmine having any abuse potential.

Q. Who should not take Neostigmine?

Neostigmine should not be taken by patients who are allergic to it. Patients who are constipated or cannot urinate should avoid its use, unless advised by the doctor. This is because Neostigmine is only used for certain types of urination problems and constipation (e.g. caused by paralysis of intestine).

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App

Connect

  • Social Links
  • Want daily dose of health?
Download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.

© 2024 Tata 1mg. All rights reserved. All medicines are dispensed in compliance with the Drugs and Cosmetics Act, 1940 and Drugs and Cosmetics Rules, 1945. We do not process requests for Schedule X and habit forming drugs.