Information about Selumetinib

Selumetinib Uses

Selumetinib is used in the treatment of neurofibromatosis type 1 (NF1).

How Selumetinib works

Selumetinib works by blocking a protein called MEK, which is part of a system in the body that controls cell growth. In neurofibromatosis type 1 (NF1), this system can become too active because of a genetic change, causing tumors called plexiform neurofibromas to grow. By turning off MEK, Selumetinib helps slow down or shrink these tumors, reducing symptoms like pain or difficulty moving, and improving the patient’s daily life.

Common side effects of Selumetinib

Vomiting, Rash, Abdominal pain, Diarrhea, Nausea, Dry skin, Fatigue, Musculoskeletal (bone, muscle or joint) pain, Fever, Stomatitis (Inflammation of the mouth), Headache, Paronychia, Itching
CONTENT DETAILS
Written By
PGDHHM, BDS
Reviewed By
MBA, MBBS
Last updated
19 Dec 2024 | 11:25 AM (UTC)

We provide you with authentic, trustworthy and revelant information

Want to know more

Available Medicine for Selumetinib

KoselugoAstraZeneca
436050 to ₹10901252 variant(s)

Expert advice for Selumetinib

  • Take Selumetinib exactly as prescribed and at the same time each day for maximum benefits.
  • Inform your doctor about all the medicines and supplements you are taking, and any preexisting medical conditions, to make sure it is safe for you.
  • Drink plenty of water and stay hydrated to manage nausea or diarrhea, and rest a good rest if you feel tired.
  • Make sure to attend all scheduled check-ups for blood tests and heart evaluations to track your progress and detect any potential issues early.
  • If you are of childbearing age, use reliable contraception during treatment and for a period of 1 week after stopping Selumetinib.

Frequently asked questions for Selumetinib

Selumetinib

Q. What is Selumetinib used for?

Selumetinib is used to treat children aged 2 years and older with neurofibromatosis type 1 (NF1). It is specifically prescribed for symptomatic, inoperable plexiform neurofibromas—benign tumors that can cause pain, disfigurement, or other complications.

Q. How should I take Selumetinib?

Take Selumetinib exactly as prescribed by your doctor. It may be taken with or without food. Swallow the capsules whole with water; do not crush or chew them.

Q. Can Selumetinib be taken with other medicines?

Some medicines and supplements may interact with Selumetinib, affecting how it works or increasing side effects. Let your doctor know about all the medicines you are taking, including over-the-counter drugs, vitamins, and herbal supplements.

Q. Can Selumetinib be taken during pregnancy or breastfeeding?

Selumetinib can harm an unborn baby and is not recommended during pregnancy. If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your doctor. Effective contraception should be used during treatment and for 1 week after the last dose.

Q. How will my doctor monitor my treatment?

Your doctor will perform regular check-ups, including blood tests and heart function evaluations, to ensure the medication is working and to monitor for potential side effects. These tests help adjust the dosage if needed and ensure your safety.

Q. Can Selumetinib cure Neurofibromatosis type 1 (NF1)?

Selumetinib is not a cure for NF1. It is a treatment to help manage symptoms, reduce the tumor size, and improve the quality of life for patients.

Q. How long will I need to take Selumetinib?

The duration of treatment depends on how your body responds to the medicine. Your doctor will regularly assess your progress and decide the best course of action.

Q. What should I avoid while taking Selumetinib?

While on treatment with Selumetinib, avoid St. John’s wort, grapefruit, or grapefruit juice. Additionally, avoid activities that might increase your risk of infection or injury. Be cautious if you have underlying liver or heart conditions, and keep your doctor informed of any changes in your health.

Q. Can adults take Selumetinib for NF1?

Selumetinib is primarily approved for children aged two years and older. Adults with NF1 should consult their doctor to determine if this treatment is appropriate for them.

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.